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ZaCh System S.p.A.




Country: Italy

ZaCh System S.p.A.
Via Lillo del Duca
10 – 20091 Bresso (MI) Italy
+39 02 665241

Production and R&D Sites:

ZaCh System S.p.A.
Via Dovaro
36045 Almisano di Lonigo (VI) Italy
+39 0444433111
ZaCh System S.A.
Z.l. la Croix Cadeau B.P. 10079
49242 Avrille Cedex, France
+33 24 142 7655


Contact EU and JP Custom: Nicolas Girard
Business Development Custom Synthesis
+33 241 96 66 91
nicolas.girard@zambongroup.com

Contact US Custom: Elena Kolaxidis
Business Development Custom Synthesis
+39 02 66524412
elena.kolaxidis@zambongroup.com

Contact Generics: Giovanni De Filippo
Global Sales & Marketing Generics API
+39 02 66524457
giovanni.defilippo@zambongroup.com

Contact Generics: Francesco Fico
Sales and Marketing API
Europe, Asia, Middle East and Africa
Tel. +39 02 66 524 321
francesco.fico@zambongroup.com

Contact Dossiers: Sara Lauria
Business Development generic Dossiers
+39 349 7503564
sara.lauria@zambongroup.com

Contact Dossiers: Andrea Gatti
Business Development generic Dossiers
+39 340 9357113
andrea.gatti@zambongroup.com


Phone: +39.02.66.524.338
FAX: +39.02.66.524.979
E-Mail:E-Mail this Supplier


http://www.zachsystem.com

ZaCh System, a privately-owned Italian company is a well-known manufacturer in the global market of Pharmaceutical chemicals. The company is focused in research & development, manufacturing and marketing of APis and advanced Intermediates. Our company is not only a supplier of quality products, but also a provider of total solutions that meet customer’s requirement in a tailored, flexible and creative way ever.

ZaCh System offers a wide range of technical expertise in a distinctive technological portfolio, such as chiral synthesis, ozonoylsis, metal hydride reduction capability, mercaptan chemistry, oxidation reactions, organometallic chemistry, agglomeration, spray dryer, freeze dryer and micronization.

Two facilities located in Lonigo, Italy and Avrille, France, both with R&D center, cGMP kilolab, pilot plant and manufacturing production are supporting Custom Synthesis projects and Generic API’s production in each stage of their clinical life

Our Dossier Business Unit offers the finished dosage form dossiers based on

  • In-House non Infringing process developed of a Majority of APIs
  • Internal pharmaceutical development and manufacturing capabilities

Zach actively seeks co-development opportunities with synergic partners for specific products that yield competitive advantages in the market

Zach has set up a special protocol in collaboration with Electra Sincrotrone Trieste for solving challenging “POLYMORPHISM” issues

Our manufacturing excellence is proven by adoption of both external and internal manufacturing excellence programs including:

  • cGMP Compliance
  • FDA Approval
  • ISO 14001 Certification
  • OHSAS 18001 (Safety Management System) Certification

ZaCh System. Innovation by tradition

ZaCh System S.p.A. is a wholly owned subsidiary of the Zambon Group.


Product List: 79

PON:Page:


 


APIs in Commercial Product

ABIRATERONE ACETATE
CAS:154229-18-2
prostate cancer treatment
(3beta)-17-(PYRIDIN-3-YL)ANDROSTA-5,16-DIEN-3-OL
BOSENTAN MONOHYDRATE
CAS:157212-55-01
Antihypertensive
4-TERT-BUTYL-N-[6-(2-HYDROXYETHOXY)-5-(2-METHOXYPHENOXY)-2-(PYRIMIDIN-2-YL)PYRIMIDIN-4-YL]BENZENE-1-SULFONAMIDE
CARBOCYSTEINE
CAS:638-23-3
mucolytic agent
(R)-2-AMINO-3-(CARBOXYMETHYLSULFANYL)PROPANOIC ACID
CARBOCYSTEINE LYSINE SALT MONOHYDRATE
CAS:49673-81-6
mucolytic agent
(R)-2-AMINO-3-(CARBOXYMETHYLSULFANYL)PROPANOIC ACID
CARVEDILOL
CAS:72956-09-3
antihypertensive, anti-anginal
1-9 H-CARBAZOL-4-YLOXY)-3-[[2-(2-METHOXYPHENOXY)ETHYL]AMINO]-2-PROPANOL
CARVEDILOL PHOSPHATE
CAS:610309-89-2
antihypertensive, anti-anginal
1-(9H-CARBAZOL-4-YLOXY)-3-[[2-(2-METHOXYPHENOXY)ETHYL]AMINO]-2-PROPANOL
DILTIAZEM
CAS:42399-41-7
coronary-therapeutic
Calcium antagonist
(2S-CIS]-3-(ACETYLOXY)-5-[2-(DIMETHYLAMINO)ETHYL]-2,3-DIHYDRO-2-(4-METHOXYPHENYL)-1,5-BENZOTHIAZEPIN-4(5H)-ONE
DORZOLAMIDE
CAS:120279-96-1
CAS: 130693-82-2 Dorzalamide hydrochloride
ofthtalmic antiglaucoma
(4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYCRO-6-METHYL-4H-THIENO[2,3-B]THIOPYRAN-2-SULFONAMIDE 7,7-DIOXIDE MONOHYDROCHLORIDE
GABAPENTIN
CAS:60142-96-3
anti-neuropathic pain Antiepileptic
1-(AMINOETHYL)CYCLOHEXANEACETIC ACID
N-ACETYL-L-CYSTEINE
CAS:616-91-1
mucolytic agent
NEBIVOLOL HCL
CAS:152520-56-4
Antihypertensive
Antihypertensive
[2R*[R*[R*(S*)]]]-?-?’-[iminobis(methylene)]-bis-[6-fluoro-3,4-dihydro-2H-1-Benzopyran-2-methanol] hydrochloride
NIFEDIPINE
CAS:21829-25-4
Coronary vasodilatator
1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester
OLOPATADINE
CAS:113806-05-6
Antihistamine for ophthalmic applications
{(11Z)-11-[3-(DIMETHYLAMINO)PROPYLIDENE]-6,11-DIHYDRODIBENZO[B,E]OXEPIN-2-YL}ACETIC ACID
PROPOFOL
CAS:2078-54-8
anesthetic (injectable)
2,6-BIS(1-METHYLETHYL)PHENOL
SULINDAC
Formula: 38194-50-2
Anti-inflammatory
Analgesic Antipyretic
(Z)-5-FLUORO-2-METHYL-1-[[4-(METHYLSULFINYL)PHENYL)METHYLENE]-1H-INDENE-3-ACETIC ACID
TRIMEBUTINE BASE
CAS:39133-31-8
irritable bowel sindrome
antispastic / anticholinergic
2-(DIMETHYLAMINO)-2-PHENYLBUTYL 3,4,5-TRIMETHOXYBENZOATE


Under Development

ENZALUTAMIDE
CAS:915087-33-1
Prostate Cancer Treatment
4-[3-[4-CYANO-3-(TRIFLUOROMETHYL)PHENYL]-5,5-DIMETHYL-4-OXO-2-THIOXOIMIDAZOLIDIN-1-YL]-2-FLUORO-N-METHYLBENZAMIDE
MACITENTAN
CAS:441798-33-0
Antihypertensive
Tablets
N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'propylsulfamide
RETIGABINE/EZOGABINE
CAS:150812-12-7
epilepsy, neuropathic pain
N-[2-AMINO-4-(4-FLUOROBENZYLAMINO)PHENYL]CARBAMIC ACID ETHYL ESTER 12-7
VILAZODONE
CAS:163521-12-8
Antidepressant
5-[4-[4-(5-CYANOINDOL-3-YL)BUTYL]PIPERAZIN-1-YL]BENZOFURAN-2-CARBOXAMIDE HYDROCHLORIDE


Commercial Dossiers

DORZOLAMIDE
GLAUCOMA
OPTHALMIC SOLUTION
DORZOLAMIDE + TIMOLOL
GLAUCOMA
OPTHALMIC SOLUTION
GABAPENTIN
EPILEPTIC NEUROPATHIC PAIN
Tablets
NEBIVOLOL
Antihypertensive
Tablets


Dossiers Under development

ABIRATERONE
PROSTATE CANCER
Tablets
BOSENTAN
Antihypertensive
Tablets
ENZALUTAMIDE
PROSTATE CANCER
Soft Capsules
MACITENTAN
Antihypertensive
Tablets
OLOPATADINE 0.1%
ANTIALLERGIC
OPTHALMIC SOLUTION
OLOPATADINE 0.2%
ANTIALLERGIC
OPTHALMIC SOLUTION
PROPOLNAC
Cough and Sore Throat
Sachets Syrup
TOBRAMYCIN
Antibiotic
INHALATION SOLUTION
TRIENTINE
Chelating Agent
Capsules


Specialty chemicals

(R)-5,5-DIPHENYL-2-METHYL-3,4-PROPANO-1,3,2-OXAZABOROLIDINE OR (R)-METHYL-CBS
CAS:112022-83-0
2-DIMETHYL-2-PHENYL-BUTAN-1-OL
CAS:39068-94-5
4-PHENYLBUTAN-1-OL
CAS:3360-41-6
DIETHYL-(3-PYRIDYL)-BORANE
CAS:89878-14-8
RDDP (R)-(+)-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINEMETHANOL
CAS:2223-48-32-9


Specialty chemicals under development

(2S)-3,6-DIHYDRO-2H-PYRAN-2-CARBOXYLIC ACID, ETHYL ESTER
CAS:364730-55-2
(S)-5,5-DIPPHENYL-2-METHYL-3,4-PROPANO-1,3,2-OXAZABORIDINE OR (S)-METHYL-CBS
CAS:112022-81-8
1-BENZHYDRYL-3-METHANESULFONYLOXY-AZETIDINE
CAS:33301-41-6
1-BENZHYDRYL-AZETIDIN-3-OL
CAS:1862-17-5
SDPP (S)-(-)-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINEMETHANOL
CAS:112068-01-6
TRANS-CYCLOHEXANE-1,4-DICARBOXYLIC ACID MONOMETHYL ESTER
CAS:15177-67-0


Technologies

AMINO ACIDS PROTECTION AND DERIVATIZATION
ASYMMETRIC SYNTHESIS
CATALYTIC HYDROGENATION
CHIRAL SYNTHESIS
CRYOGENIC CARBANION CHEMISTRY
CYANATION
ENZYMATIC CHEMISTRY
EPOXIDE SYNTHESIS
FREEZE DRYER
HETEROCYCLIC CHEMISTRY
HOFFMAN REARRANGEMENT AND DEGRADATION
IN-SITU COREY REDUCTION
ION EXCHANGE CHROMATOGRAPHY
METAL HYDRIDE REDUCTIONS
O-DEMETHYLATION
ORGANOMETALLIC CHEMISTRY
OZONOLYSIS
POLYMORPHISM AND SOLID STATE DEVELOPMENT
SPRAY DRYER
SULFUR CHEMISTRY


Keywords

BOSENTAN MONOHYDRATE
CARBOCYSTEINE
CARBOCYSTEINE LYSINE SALT MONOHYDRATE
CARVEDILOL
DILTIAZEM
MACITENTAN
N-ACETYL-L-CYSTEINE
NIFEDIPINE
OLOPATADINE
PROPOFOL
RETIGABINE
SULINDAC
TRIMEBUTINE BASE
TRIMEBUTINE MALEATE
VILAZODONE


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