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Symphony Pharma Life Sciences




Country: India

Symphony Pharma Life Sciences Pvt Ltd
Discovery Zone, SP Biotech Park,
Beside ICICI Knowledge Park,
Phase - I, Genome Valley,
Turkapally (V), Shamirpet (M),
R. R. Dist. - 500078
Hyderabad (India)


Phone: +91-40-23480340 (India)
Phone 2: 609-474-8300 (USA)
E-Mail:E-Mail this Supplier

Contact: Dr. C. Prabhakar

http://www.symphonylifesciences.com

Symphony is a technology driven organization with flexible approach, in-depth synthetic chemistry skills, analytical competency and expertise in medicinal chemistry, process research, process optimization, process validation, scale-up and large scale manufacturing to support customer’s NCE and API development programs.

Symphony has dynamic team of professionals with brilliant scientific skills, project management capabilities and hands on experience to handle NCEs and regulatory requirements upholding confidentiality and safety standards. It has excellent technical capabilities to deliver diverse chemistries from R&D to commercial scale and provides high quality cost effective support to drug discovery, CMC, clinical and generic programs to Pharmaceutical and Biotech companies.

The team has shaped up track record of delivering couple of NCE Projects to his customer in a record time, right from the conceptual stage to multi-kilo scale. Likewise, there are many significant achievements in this short span leading to customer delight and satisfaction.

Services.... CRAMS

  • Contract Research … FTE
  • Custom Synthesis
  • Contract Manufacturing

Project Profile

  • Pre-clinical and clinical supply of NCEs and its Intermediates
  • Process research/ improvement/validations
  • Non infringing route development
  • Medicinal chemistry.. Libraries/Analogues
  • API development
  • Intermediates
  • Key starting materials
  • Multi-step synthesis / Building blocks
  • Impurities/ Reference standards
  • Analytical method development and validations

Building Blocks and Intermediates

  • Bicyclo compounds
  • Thiophenes
  • Quinoxalines
  • Pyrazoles
  • Imidazoles
  • Pyridines
  • Miscellaneous

Technologies

Organo-mettallic Chemistry

  • n-BuLi handling
  • LDA handling
  • Grignard reaction

Hazardous Chemistry

  • Cyanation
  • Nitration
  • LAH reaction
  • AlCl3 handling
  • Sodium metal/hydride/Azide handling
  • Bromination/ Chlorination (POCl3, PCl5, SOCl2, Cl2, Br2, HBr)

Coupling Reactions

  • Suzuki coupling
  • Heck coupling
  • Sonogashira coupling
  • Amide coupling (DCC, EDC.HCl etc)

Specialized Chemistry

  • Multi-step synthesis
  • Carbohydrate chemistry
  • Cryogenic reactions (-70°C)
  • Heterocyclic chemistry
  • Polymorphic study : Crystallization/Salt formation

Miscellaneous

  • Cyclization
  • Hydrogenation/ Dehydrogenation
  • Chiral Chemistry
  • Friedel-craft reactions
  • Column chromatography
  • High vacuum distillations
  • Alkylation
  • Diazotization
  • Sulfonation (ClSO3H, MeSO2Cl)

Product List: 92

PON:Page:


 


Intermediates and Building Blocks

(4-FLUORO- 2-METHOXYPHENYL) METHANAMINE
(E)-TERT-BUTYL 3-(2-AMINO-5-BROMOPYRIDIN-3-YL)ACRYLATE
1, 4-BIBROMOPENTANE
CAS:626-87-9
1-(2-(4-(CHLOROMETHYL)PHENOXY)ETHYL)- AZEPANE
CAS:223251-25-0
1-(4-(BENZYLOXY)PHENYL)-2-BROMOPROPAN-1-ONE
CAS:35081-45-9
1-(4-(BENZYLOXY)PHENYL)PROPAN-1-ONE
1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIOC ACID
CAS:77169-11-0
10-PHENYL-1-DECANOL
CAS:62607-69-6
2,3-DIHYDROXY-4-METHOXYBENZALDEHYDE
CAS:4055-69-0
2,5-DI BROMONICOTINALDEHYDE
CAS:852181-11-4
2,6-DIMETHOXYPYRIDINE-3-CARBOXYLIC ACID
CAS:16727-43-8
2-(1H-IMIDAZOL-5-YL) ACETIC ACID HYDROCHLORIDE
CAS:3251-69-2
2-(4-CHLOROPHENYLTHIO)ACETONITRILE
CAS:18527-19-0
2-(METHYLTHIO)-OXAZOLO(5,4-C)PYRIDINE
CAS:169205-96-3
2-ALLYL-4,6-DIBENZOYLRESORCINOL
CAS:102593-74-8
2-AMINO-3,5-DIBROMOPYRIDINE
CAS:35486-42-1
2-AMINO5-BROMO-3-IODOPYRIDINE
CAS:381233-96-1
2-BROMO-3-HYDROXY-4METHOXY- BENZALDEHYDE
2-BROMO-4-CYANO TOLUENE
2-BROMO-4-CYANOBENZALDEHYDE
CAS:89891-69-0
2-BROMOPHENYLACETONE
CAS:21906-31-0
2-BROMOPYRIDINE-4-CARBOXALDEHYDE
CAS:118289-17-1
2-BROMOQUINOXALINE
CAS:36856-91-4
2-CYANO-3-AMINOPYRIDINE
CAS:42242-11-5
2-CYANO-6-METHOXYBENZOTHIAZOLE
CAS:943-03-3
2-FLUORO-4-METHOXYBENZONITRILE
CAS:94610-82-9
2-MERCAPTOOXAZOLO(5,4-C)PYRIDINE
2-QUINOXALINYL BORONIC ACID
CAS:499769-90-3
3-(4-FLUOROPHENYLTHOI)-2-METHYL-PROPANOIC ACID
3-ACETYLTHIOPHENE
CAS:1468-83-3
3-BENZYL-3-AZA-BICYCLO[3.1.0]HEXAN-6-AMINE
3-BENZYL-6-NITRO-3-AZA-BICYCLO[3.1.0]- HEXANE
3-BENZYL-6-NITRO-3-AZA-BICYCLO[3.1.0]HEXANE-2,4-DIONE
3-BROMO-2,6-DIMETHOXYPYRIDINE
CAS:13445-16-4
3-HYDROXYISOQUINOLINE
CAS:7651-81-2
3-IODO-4-METHOXYBENZOIC ACID
CAS:68507-19-7
3-METHYL-5-(TRIFLUOROMETHYL)PYRAZOLE
CAS:10010-93-2
4,4'-DINONYL-2,2'-BIPYRIDINE
CAS:142646-58-0
4,6-DIBENZOYL RESORCINOL
4,6-DIPHENYL-2H-PYRAN-2-ONE
CAS:17352-52-0
4-(BENZYLOXY)BENZENAMINE
CAS:51388-20-6
4-(PIVALOYLAMINO)PYRIDINE
CAS:70298-89-4
4-AMINO-2-HYDROXYPYRIDINE
CAS:52334-53-9
4-BROMO-1-DIFLUOROMETHOXY- 2-METHYL-BENZENE
CAS:88327-32-0
4-BROMOPHENYLACETONE
CAS:6186-22-7
4-FLUORO-1-METHYL-2-NITROBENZENE
CAS:446-10-6
4-FLUORO-2-NITRO-BENZYLBROMIDE
CAS:76437-44-0
4-ISOPROPYLBIPHENYL
CAS:7116-95-2
4-NITRO PYRAZOLE-3-CARBOXYLICACID
CAS:5334-40-7
5-AMINO-6-NITRO-QUINOLINE
CAS:35975-00-9
5-BROMO-1H-PYRROLE(2,3-B)PYRIDINE
CAS:183208-35-7
5-BROMO-3-METHYL-(5-TRIFLUOROMETHYL)-PYRAZOLE
5-BROMOTETRALOL
CAS:92013-31-5
5-BROMOTETRALONE
CAS:68449-30-9
6-AMINO-7-BROMOBENZOTHIAZOLE
6-AMINOBENZOTHIAZOLE
CAS:533-30-2
6-AMINOMETHYLQUINOLINE
6-BROMO-1,2-DIHYDRONAPTHANE
CAS:75693-17-3
6-BROMO-1,8-NAPHTHYRIDIN-2(1H)-ONE
CAS:72754-05-3
6-NITROBENZOTHIAZOLE
CAS:2942-06-5
7-BROMOBENZOTHIAZOLE
CAS:767-70-4
7-BROMOTETRALOL
CAS:75693-15-1
7-BROMOTETRALONE
CAS:32281-97-3
BENZENEPROPANOIC ACID-2-FLUORO ETHYL ESTER
CAS:39856-89-8
CARBAMICACID 3-AZA-BICYCLO[3.1.0]HEX-6-YL-1,1-DIMETHYLETHYL ESTER
ETHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLATE
CAS:113502-46-8
ETHYLA,4-DIBROMOPHENYLACETATE
METHYL-3-IODO-4-METHOXY BENZOATE
CAS:35387-93-0
METHYL-4-METHOXY BENZOATE
CAS:121-98-2
N-(3-HYDROXYPYRIDINE-4-YL)PIVALAMIDE
CAS:169205-93-0
N-(5-BROMO-3-(2-(TRIMETHYLSILYL)ETHYNYL)-PYRIDIN-2-YL)ACETAMIDE
N-(5-BROMO-3-IODOPYRIDIN-2-YL)ACETAMIDE
N-(5-BROMO-3-IODOPYRIDIN-2-YL)PIVALAMIDE
N-BENZYL MALEIAMIDE
CAS:1631-26-1
N-BENZYL-2,2-DIETHOXYACETAMIDE
O-BENZYL HYDROXYLAMINE HYDROCHLORIDE
CAS:2687-43-6
QUINOXALIN-2(1H)-ONE
CAS:1196-57-2
TERT-BUTYL 3-BENZYL-3-AZA-BICYCLO[3.1.0]- HEXAN-6-YLCARBAMATE
TETRAHYDROCURCUMIN
CAS:36062-04-1


Impurities

(3-THIENYL)ETHYL-P-TOLUENE SULPHONATE
5-AZA CYTIDINE IMPURITY
ANASTRAZOLE IMPURITY-B
ANASTRAZOLE IMPURITY-E
BICALUTAMIDE IMPURITY-A
BICALUTAMIDE IMPURITY-B
BICALUTAMIDE IMPURITY-C
BICALUTAMIDE IMPURITY-I
PENTAPRAZOL-IMPURITY-D (R-ISOMER)
PENTAPRAZOL-IMPURITY-D (S-ISOMER)
TELMISARTAN IMP-E
TELMISARTAN IMP-F
TELMISARTAN IMP-G


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