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Target Molecule Corp. (TargetMol)




Country: USA

USA: One Boston Place, Suite 2600,
Boston, MA 02108 USA

China: Level 4, No 228, Jiangchang San Road, Shanghai, 200436


Phone: 617-933-7262
Phone 2: 86-021-33632979 (China)
FAX: 857-239-8801
E-Mail:E-Mail this Supplier

Contact: Victor Wang

http://www.targetmol.com

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, specializing in chemical and biological research products and service to meet the research needs of global customers. With the help of fast and efficient global supply chain, professional and rigorous procurement process and timely dynamic news of products, you will save more time with less cost and lead in drug discovery and screening.

Drug screening drug design and virtual screening, target validation, model establishment, high-throughput screening, structure optimization

Pharmacological research in vivo and in vitro testing of compounds to identify new uses for known drugs

Signaling pathways stem cell, protein tyrosine kinase, epigenetics, GPCR, MAPK signaling

Cell research pluripotent stem cell induction, cell signaling transduction, cell inflammation, oncology


Product List: 3,933

PON:Page:1 | 2 | 3 |


 


Libraries

ADRENERGIC LIBRARY
L2700
Adrenergic Library contains 129 kinds of compounds, which target for adrenergic receptor specifically and are used for drug screening.
ANTI-CANCER LIBRARY
L2100
A unique collection of 975 tumor associated compounds, used in cancer related research and drug screening for high throughput screening, high content screening.
ANTI-DIABETIC LIBRARY
L1900
Anti-diabetic Library contains 69 bioactive compounds aliquoted to 96-well plates, ideal for screening and neurodegenerative diseases mechanism research.
ANTI-INFECTION COMPOUND LIBRARY
L1800
Anti-infection Compound library contains 423 kinds of antiviral, antibacterial and antiparasitic drugs for HTS and HCS, as well as drug target and other Pharmaceutical development fields.
ANTI-INFLAMMATION LIBRARY
L4300
A unique collection of 247 bioactive anti-inflammation compounds for drug screening, drug target identification, and other pharmaceutical-related applications.
ANTI-VIRUS COMPOUND LIBRARY
L1700
Contains 116 kinds of molecular for drug research and other Pharmaceutical development fields.
ANTIBIOTICS LIBRARY
L4400
A collection of 243 specific compounds with defined antibiotic properties for drug screening, drug target identification, and other pharmaceutical-related applications.
ANTIFUNGAL COMPOUND LIBRARY
L4500
A unique collection of 67 antifungal small molecules for high throughput screening including drugs that act on the fungal induced disease and products that target for antifungal related receptors.
APOPTOSIS COMPOUND LIBRARY
L9000
Apoptosis Compound Library contains 78 compounds related with apoptosis signaling pathways, which are most used in tumorigenesis and anti-cancer drug screening.
APPROVED DRUG LIBRARY
L1000
1700 approved drugs are used to discover their more function, suitable for old drug research, new targets mechanism and positive compound comparison and so on.
AUTOPHAGY LIBRARY
L3200
A unique collection of 254 compounds related with cell autophagy, used in the study of autophagy, HTS, HCS.
BIOACTIVE COMPOUND LIBRARY
L4000
Contains more than 3,071 small molecule compounds, pays more attention on their targets. All compounds have targets description, which is the key point to drug screening.
BIOACTIVE LIPID LIBRARY
L7000
The Bioactive Lipid Library contains 112 bioactive lipids aliquoted to 96-well plates.
CLINICAL COMPOUND LIBRARY
L3400
A unique collection of 480 compounds, all of which have been permitted into clinical phase.
CNS LIBRARY
L2600
CNS Library contains 600 kinds of compounds, which target for central nervous system and are used for neurologic diseases drug screening.
CYTOKINES INHIBITORS LIBRARY
L4700
A unique collection of 170 inhibitors of cytokines for high throughput screening (HTS) and high content screening (HCS).
DNA DAMAGE & REPAIR LIBRARY
L3900
A unique collection of 213 DNA Damage and Repair related compounds for high throughput screening (HTS) and high content screening (HCS).
ENDOCRINOLOGY-HORMONES LIBRARY
L2400
Contains 186 compounds related with Endocrinology/ Hormones signaling pathways, used in the study of human endocrine system and relevant disease drug screening for HTS and HCS.
EPIGENETICS INHIBITOR LIBRARY
L1200
Epigenetics library contains 135 compounds for epigenetic research, related testing, HTS and HCS.
FDA-APPROVED DRUG LIBRARY
L4200
1068 FDA-approved drugs
GPCR COMPOUND LIBRARY
L1500
Contains 356 active compounds related with G protein and G protein coupled receptors, used for GPCR targeted drug research and drug screening.
HISTAMINE & MELATONIN LIBRARY
L3300
The histamine & melatonin library contains 93 bioactive compounds, ideal for drug screening, and for research into the mechanisms of neurodegenerative diseases.
HUMAN ENDOGENOUS LIGAND LIBRARY
L2500
Contains 41 biological active compounds related with endogenous metabolism, which is used for the study of endogenous metabolic diseases and new drug screening.
INHIBITOR LIBRARY
L2000
Contains over 2672 active compounds,which can be used in not only specific research but also high-throughput screening and high-content screening.
ION CHANNEL INHIBITOR LIBRARY
L2300
Contains 263 small molecule inhibitors related with ion channel, which can be used for high throughput screening and high content screening.
KINASE INHIBITORS LIBRARY
L1600
Contains 481 kinds of kinase inhibitors, targeted for specific protein kinase for high-throughput screening and high content screening.
MAPK INHIBITOR LIBRARY
L1400
Contains 56 bioactive compounds related with MAPK pathway, for scientific research and drug screening.
NATURAL COMPOUND LIBRARY
L6000
Contains more than 640 compounds in natural compound library, from the nature of biological separation, extraction of organic compounds in the body.
OXIDATION-REDUCTION LIBRARY
L2900
Contains 71 bioactive compounds aliquoted to 96-well plates, ideal for screening or identifying mechanism research.
PI3K/AKT/MTOR INHIBITOR LIBRARY
L1300
The PI3K/Akt/mTOR inhibitor library consists of 109 small molecular compounds; they are used in the study of the PI3K/Akt/mTOR signaling pathway, and for relevant drug screening.
PROTEASE INHIBITOR LIBRARY
L1100
Contains 69 small molecule inhibitors related with protease and proteasome, for scientific research and drug screening.
SELECTED PLANT-SOURCED COMPOUND LIBRARY
L4600
A unique collection of Selected plant-sourced compounds including 333 products that derived from 165 plant species.
SEROTONIN LIBRARY
L2800
Contains 114 kinds of compounds, which target for 5-HT receptor and are used for neurologic diseases drug screening.
STEM CELL LIBRARY
L8000
Stem Cell Library contains 150 small molecular compounds used for stem cell signaling pathway research and new drug screening.
THE HEMATOPOIETIC TOXICITY LIBRARY
L3100
A focused collection of 104 compounds with defined and diverse hematopoietic toxicity, including myelosuppression, neutropenia, leukopenia, anemia, and many more.
TYROSINE KINASE INHIBITORS LIBRARY
L2200
Contains 159 compounds correspondingly, which is used to research related diseases and drug screening.


Molecules

(+)-BICUCULLINE
CAS:485-49-4
Formula: C20H17NO6
T2850
99%+
Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.
(+)-CAMPHOR
CAS:464-49-3
Formula: C10H16O
T0882
98%
Camphor is readily absorbed through the skin producing either a coolness or warmth sensation by activating the ion channel TRPV3,and acts as slight local anesthetic and antimicrobial substance. There are anti-itch gels and cooling gels with camphor as the
(+)-CATECHIN HYDRATE
CAS:225937-10-0
Formula: C15H14O7
T2778
98%
An antioxidant flavonoid of plant origin; a free radical scavenger,preventing free radical-mediated damage in a variety of biological systems. For example,at physiological pH catechin suppressed DNA strand breaks by hydroxyl radicals.
(+)-EMETINE 2HYDROCHLORIDE HYDRATE
CAS:7083-71-8
Formula: C29H40N2O42HClH2O
T0982
98%
Emetine is a drug used as both an anti-protozoal and to induce vomiting. It is produced from the ipecac root.
(+)-FANGCHINOLINE
CAS:436-77-1
Formula: C37H40N2O6
T3122
98%
Extracted from Stephania tetrandra S. Moore;Store the product in sealed,cool and dry condition
(+)-JQ-1
CAS:1268524-70-4
Formula: C23H25ClN4O2S
T2110
98%
(+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family.
(+)-USNIACIN
CAS:7562-61-0
Formula: C18H16O7
T6354
98%
(+)-Usniacin is a naturally occurring dibenzofuran derivative found in several lichen species.
(-)-BLEBBISTATIN
CAS:856925-71-8
Formula: C18H16N2O2
T6038
98%
(-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 M, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly.
(-)-EPICATECHIN
CAS:490-46-0
Formula: C15H14O6
T2856
95%
Extracted?from?Acacia catechu (L.F.) Willd peeled branches;Store?the?product?in?sealed,?cool?and?dry?condition
(-)-EPICATECHIN GALLATE
CAS:1257-08-5
Formula: C22H18O10
T2732
98%
Extracted from Green tea;Suitability:Water;Store the product in sealed,cool and dry condition
(-)-EPIGALLOCATECHIN
CAS:970-74-1
Formula: C15H14O7
T2987
98%
Extracted from Green tea;Suitability:Methanol,ethanol;Store the product in sealed,cool and dry condition
(-)-EPIGALLOCATECHIN GALLATE
CAS:989-51-5
Formula: C22H18O11
T2988
95%
(-)-Epigallocatechin gallate (EGCG), the major catechin accounting for 59% of the total catechins in green tea, is a powerful antioxidant as well as an antiangiogenic and antitumor agent. EGCG has been studied for its role in the chemoprevention of a wild
(-)-HUPERZINE A
CAS:102518-79-6
Formula: C15H18N2O
T3026
98%+
(-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonist. Phase 4.
(-)-MK 801 MALEATE
CAS:121917-57-5
Formula: C16H15NC4H4O4
T6352
98%
MK-801 is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.
(-)-P-BROMOTETRAMISOLE OXALATE
CAS:62284-79-1
Formula: C13H13BrN2O4S
T6353
98%
(-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor.
(-)-SPARTEINE SULFATE PENTAHYDRATE
CAS:6160-12-9
Formula: C15H38N2O9S
T0792
Sparteine is a class 1a antiarrhythmic agent; a sodium channel blocker. It is an alkaloid and can be extracted from scotch broom. It is the predominant alkaloid in Lupinus mutabilis, and is thought to chelate the bivalents calcium and magnesium. It is
(2-CHLOROPHENYL)PHENYL-METHANONE
CAS:5162-03-8
Formula: C13H9ClO
T0633
2-Chlorobenzophenone is used as pharmaceutical intermediate.
(20S)-PROTOPANAXADIOL
CAS:30636-90-9
Formula: C30H52O3
T2799
98%
Extracted from Panax ginseng C. A. Mey.;Suitability:Acetone,DMSO;Store the product in sealed,cool and dry condition
(2S)-PROTOPANAXATRIOL
CAS:34080-08-5
Formula: C30H52O4
T2810
99%+
Protopanaxatriol (PPT) is an organic compound characterizing a group of ginsenosides. It is a dammarane-type tetracyclic triterpene sapogenins found in ginseng (Panax ginseng) and in notoginseng (Panax pseudoginseng).
(R)-(+)-ATENOLOL
CAS:56715-13-0
Formula: C14H22N2O3
T0007L
99%
A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
(R)-(+)-LIMONENE
CAS:5989-27-5
Formula: C10H16
T3241
N/A
(R)-(-)-PHENYLEPHRINE HYDROCHLORIDE
CAS:61-76-7
Formula: C9H14ClNO2
T0453
98%
Phenylephrine hydrochloride is a selective a1-adrenergic receptor agonist.
(R)-BACLOFEN
CAS:69308-37-8
Formula: C10H12ClNO2
T6355
98%
(R)-baclofen is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.
(R)-LANSOPRAZOLE
CAS:138530-94-6
Formula: C16H14F3N3O2S
T1021
99%
Dexlansoprazole is a Proton Pump Inhibitor.
(R)-NAPROXEN
CAS:23979-41-1
Formula: C14H14O3
T0855
95%
An anti-inflammatory agent with analgesic and antipyretic properties. Both the acid and its sodium salt are used in the treatment of rheumatoid arthritis and other rheumatic or musculoskeletal disorders, dysmenorrhea, and acute gout.
(R)-NEPICASTAT HCL
CAS:195881-94-8
Formula: C14H15F2N3SHCl
T6356
98%
(R)-Nepicastat HCl, the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine--hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter recep
(R)-P7C3-OME
CAS:1235481-43-2
Formula: C22H20Br2N2O2
T1990
98%
P7C3 is a drug related to latrepirdine (dimebon), which has neuroprotective and proneurogenic effects, and may be potentially useful for the treatment of Alzheimer's disease and similar neurodegenerative disorders.The precise mechanism of action through w
(R)-RUXOLITINIB
CAS:941678-49-5
Formula: C17H18N6
T1829
98%
Ruxolitinib(INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3.
(S)-(+)-CARVONE
CAS:2244-16-8
Formula: C10H14O
T3245
N/A
(S)-(+)-Carvone is main consitituent of caraway oil and pineapple seed oil
(S)-(+)-IBUPROFEN
CAS:51146-56-6
Formula: C13H18O2
T0448
98%
S(+)-Ibuprofen is capable of inhibiting cyclooxygenase (COX) at clinically relevant concentrations, R(-)-ibuprofen is not a COX inhibitor.
(S)-(+)-KETOPROFEN
CAS:22161-81-5
Formula: C16H14O3
T0839L
98%
Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
(S)-CLOPIDOGREL HYDROGEN SULFATE
CAS:135046-48-9
Formula: C16H16ClNO2S.H2SO4
T0182L2
98%
Clopidogrel, an antiplatelet agent structurally and pharmacologically similar to ticlopidine, is used to inhibit blood clots in a variety of conditions such as peripheral vascular disease, coronary artery disease, and cerebrovascular disease. Clopidogr
(S)-CRIZOTINIB
CAS:1374356-45-2
Formula: C21H22Cl2FN5O
T6357
98%
(S)-crizotinib, the (S)-enantiomer of crizotinib, is a potent MTH1 (NUDT1) inhibitor with IC50 of 72 nM.
(S)-RUXOLITINIB
CAS:1160597-27-2
Formula: C17H18N6
T3066
100%
Ruxolitinib (INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3.
(S)-TIMOLOL MALEATE
CAS:26921-17-5
Formula: C17H28N4O7S
T0475
98%
A beta-adrenergic antagonist similar in action to propranolol. The levo-isomer is the more active. Timolol has been proposed as an antihypertensive, antiarrhythmic, antiangina, and antiglaucoma agent. It is also used in the treatment of migraine disorders
=111:3034
CAS:141-01-5
Formula: C4H2FeO4
T0001
90%
Iron(II) fumarate, also known as ferrous fumarate, is the iron(II) salt of fumaric acid, occurring as a reddish-orange powder, used to supplement iron intake.
1,1-BIS(METHYLTHIO)-2-NITROETHYLENE
CAS:13623-94-4
Formula: C4H7NO2S2
T1345
98%+
Bis(methylthio)-2-nitroethylene is an organic compound.
1,2-DIPHENYLHYDRAZINE
CAS:122-66-7
Formula: C12H12N2
T0605
96%
Pharmaceutical industry for the production of antipyretic analgesics bute; dye industry used in the manufacture of benzidine dyes , etc.
1,3-DIPHENYLUREA
CAS:102-07-8
Formula: C13H12N2O
T2716
98%
1,3-Diphenylurea is involved with Epoxide hydrolase activity.
1-(2-HYDROXYETHYL)IMIDAZOLIDINE-2-THIONE
CAS:932-49-0
Formula: C5H10N2OS
T0545
98%
Used as pharmaceutical intermediates
1-(3-CHLOROPHENYL)PIPERAZINE HYDROCHLORIDE
CAS:13078-15-4
Formula: C10H14Cl2N2
T0615
98%+
Used for synthesis of Etoperidone, trazodone, Nefazodone, etc.
1-AMINOHYDANTOIN HYDROCHLORIDE
CAS:2827-56-7
Formula: C3H6ClN3O2
T0668
98%
1-Amino Hydantoin Hydrochloride is an organic compound.
1-AZAKENPAULLONE
CAS:676596-65-9
Formula: C15H10BrN3O
T6358
98%
1-Azakenpaullone is a potent and selective GSK-3 inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25.
1-DOCOSANOL
CAS:661-19-8
Formula: C22H46O
T0884
95%
Docosanol is a drug used for topical treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters). A saturated 22-carbon aliphatic alcohol, docosanol exhibits antiviral activity against many lipid enveloped viruses i
1-ETHYL-2-BENZIMIDAZOLINONE
CAS:10045-45-1
Formula: C9H10N2O
T2604
95%
1-Ethyl-2-benzimidazolinone is a calium channel agonist.
1-HEXADECANOL
CAS:36653-82-4
Formula: C16H34O
T6359
98%
1-Hexadecanol is a fatty alcohol used to make other chemicals.
1-INDANONE
CAS:83-33-0
Formula: C9H8O
T0564
98%+
The intermediate od Indinavir
1-METHYLIMIDAZOLE
CAS:616-47-7
Formula: C4H6N2
T0575
99%
Used as intermediates in organic synthesis and resin curing agent, binder, etc
1-METHYLINDAZOLE-3-CARBOXYLIC ACID
CAS:50890-83-0
Formula: C9H8N2O2
T1369
98%+
it is an excellent solvent with proper boiling point.
1-NM-PP1
CAS:221244-14-0
Formula: C20H21N5
T2153
98%
1NM-PP1(PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors(IC50=28 uM vSrc; 4.2 nM v-Src-as1 I338G).
1-PHENYL-1,2-ETHANEDIOL
CAS:93-56-1
Formula: C8H10O2
T1346
98%+
O-benzyl oxime ether derivatives and their use as pesticides.
1-UNDECENOIC ACID
CAS:112-38-9
Formula: C11H20O2
T0306
98%
Undecylenic acid is an organic unsaturated fatty acid pyrolysis product of ricinoleic acid from castor oil. It is used in the manufacture of pharmaceuticals, cosmetics and perfumery, including antidandruff shampoos, antimicrobial powders and as a musk in
1-UNDECENOIC ACID ZINC SALT
CAS:557-08-4
Formula: C22H38O4Zn
T0744
98%
A synthetic antifungal agent.
10,11-DIHYDROCARBAMAZEPINE
CAS:3564-73-6
Formula: C15H14N2O
T0600
99%
Used as pharmaceutical intermediates
10-DEACETYLBACCATIN III
CAS:32981-86-5
Formula: C29H36O10
T2197
100%
10-DAB (also known as 10-Deacetylbaccatin) is an intermediate used for the preparation of taxol, an anti-leukemic and tumor-inhibiting agent isolated from the inner bark of the Pacific yew tree Taxus brevifolia as well as other species of the genus Taxus.
10-HYDROXY-2-DECENOIC ACID
CAS:14113-05-4
Formula: C10H18O3
T3250
N/A
10-HAD promotes neurogenesis of neural stem/progenitor cells (cells capable of differentiating into neurons, astrocytes, or oligodendrocytes)?in vitro?and could provide an effective method to treat and prevent neurological disorders.
10-HYDROXYCAMPTOTHECIN
CAS:19685-09-7
Formula: C20H16N2O5
T2764
98%
An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
10058-F4
CAS:403811-55-2
Formula: C12H11NOS2
T3048
98%
10058-F4 is a cell-permeable thiazolidinone that specificallly inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression; induces cell-cycle arrest and apoptosis.
16,17-EPOXY-21-ACETOXYPREGNENOLONE
CAS:28444-97-5
Formula: C23H32O5
T3225
98%
n/a
16,17-EPOXYPREGNENOL
CAS:974-23-2
Formula: C21H30O3
T3222
98%
n/a
16,17-EPOXYPREGNENOLONE ACETATE
CAS:34209-81-9
Formula: C23H32O4
T3219
95%
Can be produced by Burkholderia cepacia SE-1
16BETA-METHYL-16ALPHA,17ALPHA-EPOXYPREGNENOLONE
CAS:1922-48-1
Formula: C22H32O3
T3224
98%
n/a
17-AAG
CAS:75747-14-7
Formula: C31H43N3O8
T6290
98%
17-AAG (Tanespimycin) is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. Phase 2.
17-BETA-ESTRADIOL-3,17-DIPROPIONATE
CAS:113-38-2
Formula: C24H32O4
T2231
98%
Estradiol dipropionate is a synthetic ester, specifically the 3,17-dipropanoyl ester, of the natural estrogen, estradiol.
17-DMAG
CAS:467214-21-7
Formula: C32H48N4O8HCl
T6297
98%
17-DMAG is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.
17-HYDROXYPROGESTERONE
CAS:68-96-2
Formula: C21H30O3
T1429
98%
17-Hydroxyprogesterone (17-OHP) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.
17-METHYLTESTOSTERONE
CAS:58-18-4
Formula: C20H30O2
T2572
99%
17a-Methyltestosterone has similar binding affinity to AR and similar androgenic and anabolic activities as testosterone.
1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID
CAS:4928-87-4
Formula: C3H3N3O2
T1371
98%+
It has been granted the patent to have property to Inhibit protein isoprenyl transferases.
2'-DEOXYADENOSINE MONOHYDRATE
CAS:16373-93-6
Formula: C10H15N5O4
T2752
99%
Deoxyadenosine is a deoxyribonucleoside. It is a derivative of the nucleoside adenosine, differing from the latter by the replacement of a hydroxyl group (-OH) by hydrogen (-H) at the 2' position of its ribose sugar moiety.
2'-DEOXYINOSINE
CAS:890-38-0
Formula: C10H12N4O4
T1709
98%+
it is used to treat HIV infection with other antiviral drugs.
2'-DEOXYURIDINE
CAS:951-78-0
Formula: C9H12N2O5
T1721
99%
2'-Deoxyuridine. An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies.
2,3,4-TRIMETHOXYBENZALDEHYDE
CAS:2103-57-3
Formula: C10H12O4
T0527
98%+
white crystal, used as medicine intermediate.
2,3-BUTANEDIONE 2-MONOXIME
CAS:57-71-6
Formula: C25H52NO4P
T2176
98%
Perifosine (KRX-0401; D-21266; NSC 639966) is a novel Akt inhibitor with IC50 of 4.7 _mu_M, targets pleckstrin homology domain of Akt.
2,3-DICHLOROANISOLE
CAS:1984-59-4
Formula: C7H6Cl2O
T1358
98%+
Substituted aminosalicylic acid amides with fungicidal effect and intermediate products for production thereof [US6380386].
2,3-DIHYDROBENZOFURANYL-5-ACETIC ACID
CAS:69999-16-2
Formula: C10H10O3
T1359
98%+
2,3-Dihydro-5-benzofuranacetic Acid is used as Pharmaceutical material and intermeidates.
2,3-DIHYDROFURAN
CAS:1191-99-7
Formula: C4H6O
T0654
99%
2,3-Dihydrofuran is a heterocyclic compound. It is one of the simplest enol ethers.
2,6-DIHYDROXYPURINE
CAS:69-89-6
Formula: C5H4N4O2
T0665
98%+
A purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. The methylated xanthine compounds c
2,6-DIMETHYLANILINE
CAS:87-62-7
Formula: C8H11N
T0652
99%
2,6-Xylidine is an aniline derivative with the chemical formula (CH3)2C6H3NH2. It is an isomer of 2,4-xylidine and 3,4-xylidine. It is a colourless liquid although commercial samples can appear to be yellow or even red.
2,8-QUINOLINEDIOL
CAS:15450-76-7
Formula: C9H7NO2
T2291
98%
n/a
2-(1-PIPERAZINYL)PYRIMIDINE
CAS:20980-22-7
Formula: C8H12N4
T1696
98%+
It is used as anti-anxiety drug.
2-(2-HYDROXYETHYL)PYRIDINE
CAS:103-74-2
Formula: C7H9NO
T0658
98%+
2-Pyridineethanol is used as an intermediate in industry.
2-(4-(4-METHOXYBENZYLOXY)PHENYL)ACETONITRILE
CAS:1016535-83-3
Formula: C15H12FNO
T3221
98%
Detail unknown.
2-(ACETYLOXY)-3-METHYLBENZOIC ACID
CAS:4386-39-4
Formula: C10H10O4
T0238
90%
It is a organic compound with molecular fomula C10H10O4.
2-(HYDROXYMETHYL)PYRIDINE
CAS:586-98-1
Formula: C6H7NO
T1112
99%
2-Pyridinylmethanol is an organic compound.
2-ACETYL-4-BUTYRAMIDOPHENOL
CAS:40188-45-2
Formula: C12H15NO3
T0634
98%+
Gray crystalline powder.
2-ACETYL-6-METHOXYNAPHTHALENE
CAS:3900-45-6
Formula: C13H12O2
T0637
98%+
Used in synthetic non-steroidal anti-inflammatory analgesic drug, the key intermediate of naproxen and naphthalene tome
2-AMINO-5-CHLOROBENZOIC ACID
CAS:635-21-2
Formula: C7H6ClNO2
T0567
98%+
Used as a pesticide and pharmaceutical intermediates
2-AMINO-5-CHLOROBENZOPHENONE
CAS:719-59-5
Formula: C13H10CLNO
T1685
98%
Used as pharmaceutical intermediates, mainly used for the preparation of librium, stability, estazolam sedative drugs
2-AMINO-5-FLUOROPHENOL
CAS:53981-24-1
Formula: C6H6FNO
T1370
98%+
It is an organic compunds with molecular fomula C6H6FNO.
2-AMINO-5-METHYL-3-THIOPHENECARBONITRILE
CAS:138564-58-6
Formula: C6H6N2S
T1376
98%+
It is an organic compunds with molecular fomula C6H6N2S.
2-AMINO-5-NITROBENZOPHENONE
CAS:1775-95-7
Formula: C13H10N2O3
T0526
98%+
An yellow crystal powder, used as industrial and organic intermediate.
2-AMINOBENZENESULFONAMIDE
CAS:3306-62-5
Formula: C6H8N2O2S
T2187
98%
Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
2-AMINOHEPTANE
CAS:123-82-0
Formula: C7H17N
T0359
98%
Tuaminoheptane is a nasal decongestant drug which is a sympathomimetic stimulant and vasoconstrictor. However, it can cause skin irritation, which limits its usefulness as a nasal decongestant. Oral preparations were once available, but are no longer prod
2-BENZOTHIAZOLAMINE
CAS:136-95-8
Formula: C7H6N2S
T1347
97%
2-Aminobenzothiazole is an organic compound.
2-BROMO-6-METHOXYNAPHTHALENE
CAS:5111-65-9
Formula: C11H9BrO
T0663
98%+
Inhibitors of serotonin reuptake
2-CHLOROPHENOTHIAZINE
CAS:92-39-7
Formula: C12H8ClNS
T0622
98%+
It is used as the intermediate of Chlorpromazine hydrochloride
2-CHLOROPYRAZINE
CAS:14508-49-7
Formula: C4H3ClN2
T2193
98%
2-Chloropyrazine is used in chemical industry.
2-HYDROXYBENZIMIDAZOLE
CAS:615-16-7
Formula: C7H6N2O
T0662
98%+
2-Hydroxybenzimidazole is used as an intermediate in industry.
2-ISOPROPYLPHENOL
CAS:88-69-7
Formula: C9H12O
T0656
98%+
2-Isopropylphenol has antioxidant property.
2-METHOXY-1,4-NAPHTHOQUINONE
CAS:2348-82-5
Formula: C11H8O3
T3008
98%
Lawsone (2-hydroxy-1,4-naphthoquinone), also known as hennotannic acid, is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well as in the flower of water hyacinth (Eichhornia crassipes).
2-METHOXY-5-SULFAMOYLBENZOIC ACID
CAS:22117-85-7
Formula: C8H9NO5S
T0561
97%
Used as intermediates in organic synthesis sulpiride
2-METHOXYBENZYLAMINE
CAS:6850-57-3
Formula: C8H11NO
T1372
98%
It is an organic compounds with molecular fomula C8H11NO.
2-METHOXYESTRADIOL
CAS:362-07-2
Formula: C19H26O3
T2220
98%
2-Methoxyestradiol (2ME2) is a drug that prevents the formation of new blood vessels that tumors need in order to grow (angiogenesis). It has undergone Phase 1 clinical trials against breast cancers. Preclinical models also suggest that 2ME2 could also be
2-METHOXYNAPHTHALENE
CAS:93-04-9
Formula: C11H10O
T0573
Used as Odor agents.
2-METHOXYPHENOTHIAZINE
CAS:1771-18-2
Formula: C13H11NOS
T0642
98%
2-Methoxy Phenothiazine is Light yellow or light gray solid.
2-METHYL-4-NITROIMIDAZOLE
CAS:696-23-1
Formula: C4H5N3O2
T0638
99%
2-Methyl-5-nitroimidazole is a kind of small molecular compounds.
2-METHYLBENZENE-1-SULFONAMIDE
CAS:88-19-7
Formula: C7H9NO2S
T0571
99%
Used for saccharin, pharmaceutical intermediates, etc
2-METHYLBENZHYDROL
CAS:5472-13-9
Formula: C14H14O
T0566
98%
Used as pharmaceutical intermediates.
2-NAPHTHOL
CAS:135-19-3
Formula: C10H8O
T0671
98%
2-Naphthol, or -naphthol, is a fluorescent colorless crystalline solid with the formula C10H7OH. It is an isomer of 1-naphthol, differing by the location of the hydroxyl group on the naphthalene ring. The naphthols are naphthalene homologues of phenol, b
2-NP
CAS:65182-56-1
Formula: C14H10N2O
T2168
98%
2-NP increased the duration of STAT1 tyrosine phosphorylation in response to IFN-gamma, and this may underlie its enhancement of STAT1-dependent transcription. Reflecting the fact that STAT1 can exert tumor-suppressive effects, 2-NP enhanced the ability o
2-PHENYLBUTYRIC ACID
CAS:90-27-7
Formula: C10H12O2
T0631
98%
2-Phenylbutyric Acid is used as an industrial intermediate.
2-PICOLINYL HYDRAZIDE
CAS:1452-63-7
Formula: C6H7N3O
T1374
98%
Isoniazid is a prodrug and must be activated by bacterial catalase. Specficially, activation is associated with reduction of the mycobacterial ferric KatG catalase-peroxidase by hydrazine and reaction with oxygen to form an oxyferrous enzyme complex. Once
2-THIOURACIL
CAS:141-90-2
Formula: C4H4N2OS
T1310
99%
Occurs in seeds of Brassica and Crucifera species. Thiouracil has been used as antithyroid, coronary vasodilator, and in congestive heart failure although its use has been largely supplanted by other drugs. It is known to cause blood dyscrasias and suspec
2-TRIFLUOROMETHYL THIOXANTHONE
CAS:1693-28-3
Formula: C14H7F3OS
T1361
98%+
It is a pale yellow crystal. with molecular fomula C14H7F3OS.
2-VINYLPYRIDINE
CAS:100-69-6
Formula: C7H7N
T0616
99%
mainly used in synthetic pyridine-styrene-butadiene latex, also used in the manufacture of silicon and Bestatin hydrochloride and other drugs.
3',4',5',5,7-PENTAMETHOXYFLAVANONE
CAS:479672-30-5
Formula: C20H22O7
T1729
98%
It is an organic compound with fomular C20H22O7.
3',4'-ANHYDROVINBLASTINE
CAS:38390-45-3
Formula: C46H56N4O8
T3022
98%
Extracted?from?Catharanthus roseus (L.)G.Don;Store?the?product?in?sealed,?cool?and?dry?condition
3,3',5-TRIIODO-L-THYRONINE
CAS:6893-02-3
Formula: C15H12I3NO4
T1653
Liothyronine is a T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodoth
3,3',5-TRIIODO-L-THYRONINE SODIUM
CAS:55-06-1
Formula: C15H11I3NNaO4
T1669
Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis.
3,3'-DIINDOLYLMETHANE
CAS:1968-05-4
Formula: C17H14N2
T2991
DIM (3,3'-diindolylmethane), a small molecule compound, is a proposed cancer preventive agent.
3,3-DIPHENYLPROPYLAMINE
CAS:5586-73-2
Formula: C15H17N
T0560
98%
Used for synthetic drugs heartache
3,4,5-TRIMETHOXYCINNAMIC ACID
CAS:90-50-6
Formula: C12H14O5
T2983
99%
n/a
3,4-DIMETHOXYBENZYL ALCOHOL
CAS:93-03-8
Formula: C9H12O3
T0657
3,4-Dimethoxybenzyl Alcohol is an organic compound.
3,4-DIMETHOXYHYDROCINNAMIC ACID
CAS:2107-70-2
Formula: C11H14O4
T1692
98%+
It is an organic compunds with molecular fomula C11H14O4.
3,5-DIHYDROXYBENZOIC ACID
CAS:99-10-5
Formula: C7H6O4
T0570
Used as intermediates in organic synthesis, and used for pharmaceuticals, synthetic resin, etc.
3,5-DIIODOTYROSINE DIHYDRATE
CAS:18835-59-1
Formula: C9H13I2NO5
T2760
98%
n/a
3-(METHYLAMINO)TOLUENE
CAS:696-44-6
Formula: C8H11N
T0557
97%
Used as dye intermediates
3-AMINO-5-METHYLISOXAZOLE
CAS:1072-67-9
Formula: C4H6N2O
T0644
97%
Pharmaceutical intermediates. Used in the production of sulfonamide drugs.
3-AMINOPROPIONITRILE FUMARATE
CAS:2079-89-2
Formula: C7H10N2O4
T2769
98%
n/a
3-CHLOROPROPIOPHENONE
CAS:936-59-4
Formula: C9H9ClO
T1342
98%+
3-Chloropropiophenone is a small molecular compound.
3-DEAZANEPLANOCIN A
CAS:102052-95-9
Formula: C12H14N4O3
T6292
98%
3-Deazaneplanocin A (DZNep) is an attractive epigenetic anticancer agent through the inhibition of the cellular enhancer of zeste homolog 2 (EZH2) protein.
3-DEAZANEPLANOCIN A (DZNEP) HCL
CAS:120964-45-6
Formula: C12H14N4O3HCl
T6360
98%
3-deazaneplanocin A (DZNeP)HCl, an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM.
3-HYDROXYFLAVONE
CAS:577-85-5
Formula: C15H10O3
T2910
99%
3-Hydroxyflavone is a chemical compound. It is the backbone of all flavonols, a type of flavonoid. It is a synthetic compound, which is not found naturally in plants.
3-INDOLEBUTYRIC ACID (IBA)
CAS:133-32-4
Formula: C12H13NO2
T6361
98%
3-Indolebutyric acid(IBA) is a plant hormone in the auxin family and is an ingredient in many commercial plant rooting horticultural products.
3-METHYLADENINE (3-MA)
CAS:5142-23-4
Formula: C6H7N5
T1879
98%
3-Methyladenine (3-MA) is a selective PI3K inhibitor for Vps34 and PI3K? with IC50 of 25 M and 60 M in HeLa cells; blocks class I PI3K consistently, whereas suppression of class III PI3K is transient, and also blocks autophagosome formation.
3-METHYLOXINDOLE
CAS:1504-06-9
Formula: C9H9NO
T0538
97%
Used as organic synthesis and medicine intermediate.
3-PYRIDINEMETHANOL
CAS:100-55-0
Formula: C6H7NO
T1299
98%
Alcohol analog of NICOTINIC ACID which is a direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and threatened GANGRENE.
3-PYRIDYLACETIC ACID HYDROCHLORIDE
CAS:6419-36-9
Formula: C7H8ClNO2
T1366
98%+
It is an organic compunds with molecular fomula C7H8ClNO2.
3PO
CAS:13309-08-5
Formula: C13H10N2O
T3260
98%
3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor
4'-(2-METHYLPROPYL)ACETOPHENONE
CAS:38861-78-8
Formula: C12H16O
T0597
97%
Used as pharmaceutical intermediates
4'-DEMETHYLEPIPODOPHYLLOTOXIN
CAS:6559-91-7
Formula: C21H20O8
T2937
98%
4'-demethylepipodophyllotoxin is a key intermediate compounds for the preparation of podophyllotoxin-type anti-cancer drugs.
4'-TERT-BUTYLACETOPHENONE
CAS:943-27-1
Formula: C12H16O
T0549
98%+
Used as pharmaceutical intermediates
4-(1H-PYRAZOL-4-YL)-7-((2-(TRIMETHYLSILYL)ETHOXY)-METHYL)-7H-PYRROLO[2,3-D]PYRIMIDINE
CAS:941685-27-4
Formula: C15H21N5OSi
T2476
100%
Detail unknown
4-(BENZYLOXY)PHENOL
CAS:103-16-2
Formula: C13H12O2
T0759
98%
Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water. The topical application of monobenzone in ani
4-AMINO-5-CHLORO-2-METHOXYBENZOIC ACID
CAS:7206-70-4
Formula: C8H8ClNO3
T0614
98%+
Used as organic synthesis and medicine intermediate.
4-AMINO-5-IMIDAZOLECARBOXAMIDE
CAS:360-97-4
Formula: C4H6N4O
T1705
98%+
An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. Compounded with orotic acid, it is used t
4-AMINOANTIPYRINE
CAS:83-07-8
Formula: C11H13N3O
T0050
Ampyrone is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. Due to the risk of agranulocytosis its use as a drug is discouraged. It is used as a reagent for biochemical reactions producing peroxides or phenols
4-AMINOBUTYRIC ACID
CAS:56-12-2
Formula: C4H9NO2
T0508
The most common inhibitory neurotransmitter in the central nervous system.
4-AMINOHIPPURIC ACID
CAS:61-78-9
Formula: C9H10N2O3
T1436
98%
4-Aminohippuric acid is a typical substrate of organic anion transport systems.
4-AMINOPHENOL
CAS:123-30-8
Formula: C6H7NO
T0648
98%
4-Aminophenol (or para-aminophenol or p-aminophenol) is the organic compound with the formula H2NC6H4OH. Typically available as a white powder, it is commonly used as a developer in black-and-white film, marketed under the name Rodinal.
4-AMINOPHENYLARSONIC ACID
CAS:98-50-0
Formula: C6H8AsNO3
T2224
98%
An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals.
4-AMINOPYRIDINE
CAS:504-24-5
Formula: C5H6N2
T0817
98%
Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients. FDA approved on January 22, 2010.
4-BIPHENYLACETIC ACID
CAS:5728-52-9
Formula: C14H12O2
T0888
98%
Felbinac (INN, or biphenylylacetic acid) is a topical medicine, belonging to the family of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs) of the arylpropionic acid class, which is used to treat muscle inflammation and arthritis. It is a
4-BUTOXYPHENOL
CAS:122-94-1
Formula: C10H14O2
T1350
98%+
4-Butoxyphenol is an organic compound.
4-CHLORO-3-METHYLPHENOL
CAS:59-50-7
Formula: C7H7ClO
T0774
99%
Chlorocresol is an activator of ryanodine receptor
4-CHLORO-4'-HYDROXYBENZOPHENONE
CAS:42019-78-3
Formula: C13H9ClO2
T1344
98%+
4-Chloro-4-hydroxybenzophenone is an organic compound.
4-CHLOROPHENOL
CAS:106-48-9
Formula: C6H5ClO
T0733
98%
Chlorophenols are commonly used as pesticides, herbicides, and disinfectants.
4-CHLOROSALICYLIC ACID
CAS:5106-98-9
Formula: C7H5ClO3
T0666
98%+
Antimicrobial compositions comprising a benzoic acid analog and a metal salt
4-CYCLOHEXYL-1-PHENYLTHIOSEMICARBAZIDE
CAS:27421-91-6
Formula: C13H19N3S
T1727
98%
n/a
4-DIETHYLAMINO-2-BUTYN-1-OL
CAS:10575-25-4
Formula: C8H15NO
T0555
98%
Used as pharmaceutical intermediates
4-FLUOROANILINE
CAS:371-40-4
Formula: C6H6FN
T0655
99%
4-fluoroaniline is used as the intermediate of medicine, dyestuff, pesticide synthesis
4-FLUOROANISOLE
CAS:459-60-9
Formula: C7H7FO
T0528
99%+
Intermediates of medicine, pesticide, liquid crystal materials.
4-FORMYLBENZOIC ACID
CAS:619-66-9
Formula: C8H6O3
T1691
98%
It is an organic compunds with molecular fomula C8H6O3.
4-HYDROXY-3-METHOXYBENZYLAMINE HYDROCHLORIDE
CAS:7149-10-2
Formula: C8H12ClNO2
T1356
Vanillylamine is an alkaloid that is an intermediate in the biosynthesis of capsaicin. Vanillylamine is produced from vanillin by the enzyme vanillin aminotransferase.
4-HYDROXY-3-METHOXYMANDELIC ACID
CAS:55-10-7
Formula: C9H10O5
T0611
Vanillyl mandelic acid (VMA) is a chemical intermediate in the synthesis of artificial vanilla flavorings[1] and is an end-stage metabolite of the catecholamines, epinephrine, and norepinephrine. It is produced via intermediary metabolites.
4-HYDROXY-3-NITROPHENYLACETIC ACID
CAS:10463-20-4
Formula: C8H7NO5
T1706
98%+
It is a small molecular drug, active to Ig heavy chain V-I region and Ig gamma-2 chain C region.
4-HYDROXYANTIPYRINE
CAS:1672-63-5
Formula: C11H12N2O2
T2225
99%
Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
4-HYDROXYBENZOIC ACID
CAS:99-96-7
Formula: C7H6O3
T2989
98%
4-Hydroxybenzoic acid is a monohydroxybenzoic acid, a phenolic derivative of benzoic acid. It is a white crystalline solid that is slightly soluble in water and chloroform but more soluble in polar organic solvents such as alcohols and acetone.
4-HYDROXYBENZOPHENONE
CAS:1137-42-4
Formula: C13H10O2
T0624
98%+
Used in organic synthesis, is an intermediates of infertility drugs Clomifene .
4-HYDROXYCHALCONE
CAS:20426-12-4
Formula: C15H12O2
T3005
96%
4-Hydroxychalcone attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.
4-HYDROXYISOPHTHALIC ACID
CAS:636-46-4
Formula: C8H6O5
T0553
98%
Used as pharmaceutical intermediates
4-ISOPROPYLPHENOL
CAS:99-89-8
Formula: C9H12O
T0620
98%+
4-Isopropylphenol is corrosive to the skin and cornea.
4-KETO 13-CIS-RETINOIC ACIDMETHYLESTER
CAS:71748-57
Formula: C20H26O3
T3203
98%
4-Keto 13-cis-Retinoic Acid is a retinoic acid metabolite in neuroblastoma.
4-METHOXY-2-OXO-1,2-DIHYDRO-PYRIDINE-3-CARBONITRILE
CAS:21642-98-8
Formula: C7H6N2O2
T1363
98%+
1,2-Dihydro-4-methoxy-2-oxo-3-pyridinecarbonitrile was reported as xanthine oxidase inhibitor.
4-METHYLMORPHOLINE N-OXIDE
CAS:7529-22-8
Formula: C5H11NO2
T0636
98%
N-Methylmorpholine N-oxide (more correctly 4-methylmorpholine 4-oxide), NMO or NMMO is an organic compound. This heterocyclic amine oxide and morpholine derivative is used in organic chemistry as a co-oxidant and sacrificial catalyst in oxidation reaction
4-METHYLUMBELLIFERONE (4-MU)
CAS:90-33-5
Formula: C10H8O3
T1391
98%
A coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY TECHNIQUES for the determination of NITRIC ACID.
4-NITRO-3-TRIFLUOROMETHYL ANILINE
CAS:393-11-3
Formula: C7H5F3N2O2
T1360
98%+
it is also called 5-Amino-2-nitrobenzotrifluoride.
4-PENTYNOIC ACID
CAS:6089-09-4
Formula: C5H6O2
T0580
n/a
4E1RCAT
CAS:328998-25-0
Formula: C28H8N2O6
T1742
98%
4E1RCat is a dual inhibitor of eIF4E:eIF4G and eIF4E:4E-BP1 interaction, and inhibits the binding of eIF4G to eIF4E with IC50 of 3.2 M.
4EGI-1
CAS:315706-13-9
Formula: C18H12Cl2N4O4S
T2665
96%
4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor by binding to eIF4E with KD of 25 M.
4SC-202 FREE BASE
CAS:910462-43-0
Formula: C23H21N5O3S
T6362
98%
4SC-202 is a selective class I HDAC inhibitor with IC50 of 1.20 M, 1.12 M, and 0.57 M for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). Phase 1.
4u8C
CAS:14003-96-4
Formula: C11H8O4
T6363
98%
48C is a potent and selective IRE1 Rnase inhibitor with IC50 of 76 nM.
5-ACETYLSALICYLIC ACID
CAS:13110-96-8
Formula: C9H8O4
T2735
98%
n/a
5-AMINO-4-IMIDAZOLECARBOXAMIDE
CAS:21299-72-9
Formula: C4H6N4O
T1722
95%
An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. Compounded with orotic acid, it is used to t
5-AMINOLEVULINIC ACID HYDROCHLORIDE
CAS:5451-09-2
Formula: C5H10ClNO3
T1662
5-Aminolevulinic acid hydrochloride is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.
5-AMINOSALICYLIC ACID
CAS:89-57-6
Formula: C7H7NO3
T0646
99%+
An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
5-AZACYTIDINE
CAS:320-67-2
Formula: C8H12N4O5
T1339
98%
A pyrimidine analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primarily into RNA. Azacytidine has been used as an antineoplastic agent.
5-FLUOROURACIL
CAS:51-21-8
Formula: C4H3FN2O2
T0984
99%+
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-FLUOROURIDINE
CAS:316-46-1
Formula: C9H11FN2O6
T1349
98%+
5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compounds comprising a pyrimidine base atta
5-HYDROXYMETHYL-2-FURALDEHYDE
CAS:67-47-0
Formula: C6H6O3
T2943
98%
Extracted from Cornus officinalis Sieb. et Zucc.;Suitability:Water,ethanol,ethyl ether,acetone,carbon tetrachloride;Store the product in sealed,cool and dry condition
5-HYDROXYTRYPTOPHAN (5-HTP)
CAS:56-69-9
Formula: C11H12N2O3
T3003
100%
5-Hydroxytryptophan (5-HTP), also known as oxitriptan (INN), is a naturally occurring amino acid and chemical precursor for the treatment of depression. Extracted from Griffonia simplicifolia;Suitability:Water;Store the product in sealed,cool and dry cond
5-METHOXYPSORALEN
CAS:484-20-8
Formula: C12H8O4
T2143
98%
Bergapten is a psoralen that can be photoactivated and is capable of crossing-linking DNA, covalently modifying proteins and lipids, and consequently inhibiting cell replication.
5-PHENYL-2,4-PENTADIENOIC ACID
CAS:1552-94-9
Formula: C11H10O2
T3006
98%
JUAREZIC ACID is also known as 5-Phenylpenta-2,4-dienoic acid.
5ALPHA-CHOLESTAN-3-ONE
CAS:566-88-1
Formula: C27H46O
T2905
97%
n/a
5BETA-PREGNANE-3ALPHA,20ALPHA-DIOL
CAS:80-92-2
Formula: C21H36O2
T1688
98%
An inactive metabolite of PROGESTERONE by reduction at C5, C3, and C20 position. Pregnanediol has two hydroxyl groups, at 3-alpha and 20-alpha. It is detectable in URINE after OVULATION and is found in great quantities in the pregnancy urine.
6-ACETAMIDOHEXANOIC ACID
CAS:57-08-9
Formula: C8H15NO3
T0436
6-Acetamidohexanoic acid is a kind of amino acids deriviate.
6-AMINOCAPROIC ACID
CAS:60-32-2
Formula: C6H13NO2
T0881
98%
(6-)e-?Aminocaproic acid is a derivative and analogue of the amino acid lysine. Aminocaproic acid is an Antifibrinolytic Agent. The physiologic effect of aminocaproic acid is by means of Decreased Fibrinolysis.
6-BENZYLAMINOPURINE
CAS:1214-39-7
Formula: C12H11N5
T1004
99%
6-Benzylaminopurine, benzyl adenine or BAP is a first-generation synthetic cytokinin that elicits plant growth and development responses, setting blossoms and stimulating fruit richness by stimulating cell division. It is an inhibitor of respiratory kinas
6-HYDROXYFLAVONE
CAS:6665-83-4
Formula: C15H10O3
T2940
98%
6-Hydroxyflavone is a flavone, a type of chemical compound. It is one of the noncompetitive inhibitors of cytochrome P450 2C9. It is reported in leaves of Barleria prionitis Linn. (a common Acanthaceae from India).[1] 6-Hydroxyflavone may have a potential
6-HYDROXYPURINE
CAS:68-94-0
Formula: C5H4N4O
T1362
100%
A purine and a reaction intermediate in the metabolism of adenosine and in the formation of nucleic acids by the salvage pathway.
6-MERCAPTOPURINE
CAS:50-44-2
Formula: C5H4N4S
T0010
98%
Mercaptopurine is a widely used anti-leukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.
6-MERCAPTOPURINE MONOHYDRATE
CAS:6112-76-1
Formula: C5H4N4S
T2201
98%
ercaptopurine is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.
6-METHOXY-2-NAPHTHOIC ACID
CAS:2471-70-7
Formula: C12H10O3
T0556
98%+
Used as pharmaceutical intermediates
6-OAU
CAS:83797-69-7
Formula: C12H21N3O2
T2036
98%
6-OAU(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay.
6-THIOGUANINE
CAS:154-42-7
Formula: C5H5N5S
T3089
98%
Thioguanine, a purine antimetabolite, inhibits DNMT1 activity through ubiquitin-targeted degradation, used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis) and organ transplant recipients
6H05
CAS:1469338-01-9
Formula: C20H30ClN3O2S3CF3COOH
T1931
98%
6H05 is a selective, and allosteric inhibitor of oncogenic K-Ras(G12C).
7,8-DIHYDROXYFLAVONE
CAS:38183-03-8
Formula: C15H10O4
T2816
98%
7,8-Dihydroxyflavone (7,8-DHF) is a naturally-occurring flavone found in Godmania aesculifolia, Tridax procumbens, and primula tree leaves.
7-AMINOCEPHALOSPORANIC ACID
CAS:957-68-6
Formula: C10H12N2O5S
T0989
98%
7-Aminocephalosporanic acid is used for synthesis of cephalosporin antibiotics and intermediates.
7-HYDROXYCOUMARIN
CAS:93-35-6
Formula: C9H6O3
T1693
98%+
It is a widespread natural product of the coumarin family. It has been reported to have antioxidant properties.
7-METHOXY-4-METHYLCOUMARIN
CAS:2555-28-4
Formula: C11H10O3
T2785
98%
It is also called 7-Methoxy-4-methylcoumarin.
7-METHYLXANTHINE
CAS:552-62-5
Formula: C6H6N4O2
T0543
98%
Used as pharmaceutical intermediates
7ACC2
CAS:1472624-85-3
Formula: C18H15NO4
T1768
98%
7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx; new antitumor treatment targeting lactate transport in cancer cells.
8-AZAGUANINE
CAS:134-58-7
Formula: C4H4N6O
T2218
98%
Azaguanine-8 is a purine analogs showing antineoplastic activity by competing with guanine in the metabolism.
8-HYDROXYQUINOLINE
CAS:148-24-3
Formula: C9H7NO
T0404
98%
An antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topic
8-HYDROXYQUINOLINE-2-CARBOXALDEHYDE
CAS:14510-06-6
Formula: C10H7NO2
T2290
95%
n/a
A 77-01
CAS:607737-87-1
Formula: C18H14N4
T2098
98%
A 77-01 is a potent inhibitor of TGF-(beta) type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.
A 83-01
CAS:909910-43-6
Formula: C25H19N5S
T3031
98%
A 83-01 is a selective inhibitor of TGF- type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 with IC50 values of 12 nM, 45 nM and 7.5 nM, respectively.
A-1210477
CAS:1668553-26-1
Formula: C46H55N7O7S
T2632
99%
A-1210477 is a potent and selective MCL-1 and Bcl-2 inhibitor with Ki and IC50 of 0.454 nM and 26.2 nM, respectively, >100-fold selectivity over other Bcl-2 family members.
A-205804
CAS:251992-66-2
Formula: C15H12N2OS2
T2254
98%
A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively.
A-438079 HYDROCHLORIDE
CAS:899431-18-6
Formula: C13H10Cl3N5
T2673
100%
A-438079 hydrochloride is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9.
A-674563
CAS:552325-73-2
Formula: C22H22N4O
T6139
98%
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
A-769662
CAS:844499-71-4
Formula: C20H12N2O3S
T2468
98%
A-769662 is a potent, reversible AMPK activator with EC50 of 0.8 M in cell-free assays, little effect on GPPase/FBPase activity.
A-803467
CAS:944261-79-4
Formula: C19H16ClNO4
T2024
98%
A-803467 is a selective NaV1.8 channel blocker with IC50 of 8 nM, blocks tetrodotoxin-resistant currents, exhibits >100-fold selectivity against human NaV1.2, NaV1.3, NaV1.5, and NaV1.7.
A-966492
CAS:934162-61-5
Formula: C18H17FN4O
T6366
98%
A-966492 is a novel and potent inhibitor of PARP1 and PARP2 with Ki of 1 nM and 1.5 nM, respectively.
A66
CAS:1166227-08-2
Formula: C17H23N5O2S2
T2418
98%
A66 is a potent and specific p110a inhibitor with IC50 of 32 nM in a cell-free assay, >100 fold selectivity for p110a over other class-I PI3K isoforms.
ABACAVIR
CAS:136470-78-5
Formula: C14H18N6O
T1267
99%
Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In v
ABACAVIR SULFATE
CAS:188062-50-2
Formula: C14H18N6O1/2H2O4S
T6367
98%
Abacavir is a commonly used nucleoside analogue with potent antiviral activity against HIV-1.
ABIETIC ACID
CAS:514-10-3
Formula: C20H30O2
T3090
85%
Abietic acid is the primary component of resin acid, is the primary irritant in pine wood and resin, isolated from rosin (via isomerization) and is the most abundant of several closely related organic acids that constitute most of rosin, the solid port
ABIRATERONE
CAS:154229-19-3
Formula: C24H31NO
T6216
98%
Abiraterone is a potent CYP17 inhibitor with IC50 of 2 nM.
ABIRATERONE ACETATE
CAS:154229-18-2
Formula: C26H33NO2
T6215
98%
Abiraterone Acetate is an acetate salt form of Abiraterone which is a steroidal cytochrome CYP17 inhibitor with IC50 of 72 nM.
ABSCISIC ACID
CAS:14375-45-2
Formula: C15H20O4
T3014
98%+
Abscission-accelerating plant growth substance isolated from young cotton fruit, leaves of sycamore, birch, and other plants, and from potatoes, lemons, avocados, and other fruits.
ABSCISIC ACID (DORMIN)
CAS:21293-29-8
Formula: C15H20O4
T6368
98%
Abscisic Acid is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth.
ABT-199
CAS:1257044-40-8
Formula: C45H50ClN7O7S
T2119
98%
ABT-737
CAS:852808-04-9
Formula: C42H45ClN6O5S2
T2099
98%
ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM in cell-free assays, respectively; no inhibition observed against Mcl-1, Bcl-B or Bfl-1. Phase 2.
ABT-751
CAS:141430-65-1
Formula: C18H17N3O4S
T1758
98%
ABT-751(E 7010) is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with IC50 of about 1.5 and 3.4 M in neuroblastoma and non-neuroblastoma cell lines, respectively.
AC-55541
CAS:916170-19-9
Formula: C25H20BrN5O3
T2370
98%
AC-55541 is a novel small-molecule protease-activated receptor 2(PAR2) agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM.
AC-BETA-ALA-OH
CAS:3025-95-4
Formula: C5H9NO3
T1373
98%
It is an organic compounds with molecular fomula C5H9NO3
AC1NS4RE
CAS:1055412-47-9
Formula: C15H13ClN2O
T2340
98%
n/a
ACALISIB (GS-9820)
CAS:870281-34-8
Formula: C21H16FN7O
T2682
100%
Acalisib (GS-9820) is a potent and selective inhibitor of PI3Kd with IC50 value of 12.7 nM
ACAMPROSATE CALCIUM
CAS:77337-73-6
Formula: C10H20CaN2O8S2
T1673
98%
Acamprosate, also known by the brand name Campral?, is a drug used for treating alcohol dependence. Acamprosate is thought to stabilize the chemical balance in the brain that would otherwise be disrupted by alcoholism, possibly by blocking glutaminergic N
ACARBOSE
CAS:56180-94-0
Formula: C25H43NO18
T0247
95%
Acarbose is an inhibitor of intestinal alpha-glucosidase, used to treat type 2 diabetes mellitus.
ACEBUTOLOL HYDROCHLORIDE
CAS:34381-68-5
Formula: C18H29ClN2O4
T1012
98%
A cardioselective beta-1 adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm, as well as weak inherent sympathomimetic action.
ACECLOFENAC
CAS:89796-99-6
Formula: C16H13Cl2NO4
T1421
98%
Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.
ACEDOBEN
CAS:556-08-1
Formula: C9H9NO3
T0315
99%
Acedoben (4-acetamidobenzoic acid) is a chemical compound with the molecular formula of C9H9NO3. It is the acetyl derivative of para-aminobenzoic acid (PABA).
ACEGLUTAMIDE
CAS:2490-97-3
Formula: C7H12N2O4
T0769
99%
Aceglutamide is a psychostimulant and nootropic used to improve memory and concentration. Chemically, it is the acetyl derivative of the amino acid L-glutamine.
ACEMETACIN
CAS:53164-05-9
Formula: C21H18ClNO6
T1467
98%
Acemetacin (Emflex) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.
ACESULFAME POTASSIUM
CAS:55589-62-3
Formula: C4H4KNO4S
T0940
98%
Acesulfame potassium is a non-nutritive sweetener.
ACETAMINOPHEN
CAS:103-90-2
Formula: C8H9NO2
T0065
98%
Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
ACETANILIDE
CAS:103-84-4
Formula: C8H9NO
T0406
98%
Acetanilide is an aniline derivative and has possess analgesic.
ACETAZOLAMIDE
CAS:59-66-5
Formula: C4H6N4O3S2
T0813
99%
One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are ex
ACETOHEXAMIDE
CAS:968-81-0
Formula: C15H20N2O4S
T0816
98%
A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide.
ACETOHYDROXAMIC ACID
CAS:546-88-3
Formula: C2H5NO2
T1592
98%
Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and doe
ACETYLCHOLINE CHLORIDE
CAS:60-31-1
Formula: C7H16ClNO2
T1221
99%
A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
ACETYLCHOLINE CHLORIDE`ACETRIZOIC ACID
CAS:85-36-9
Formula: C9H6I3NO3
T0803
98%
Acetrizoic acid is a molecule used as a contrast medium.
ACETYLCYSTEINE
CAS:616-91-1
Formula: C5H9NO3S
T0875
98%
Acetylcysteine is a derivative of cysteine; an acetyl group that is attached to the nitrogen atom. This compound is sold as a dietary supplement commonly claiming antioxidant and liver protecting effects.Acetylcysteine (also known as N-acetylcysteine or N
ACETYLLEUCINE
CAS:99-15-0
Formula: C8H15NO3
T1387
99%
Acetylleucine is a drug used in the treatment of vertigo.
ACETYLSPIRAMYCIN
CAS:24916-51-6
Formula: C45H76N2O15
T1557
98%
Acetylspiramycin targets 50S ribosome to inhibit protein synthesis.
ACETYLVANILLIN
CAS:881-68-5
Formula: C10H10O4
T2977
100%
Vanillin is a phenolic aldehyde
ACIPIMOX
CAS:51037-30-0
Formula: C6H6N2O3
T1162
98%
Acipimox is a niacin derivative used as a hypolipidemic agent. It is used in low doses and may have less marked adverse effects, although it is unclear whether the recommended dose is as effective as are standard doses of nicotinic acid. Acipimox inhibits
ACITRETIN
CAS:55079-83-9
Formula: C21H26O3
T1330
100%
An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of ETRETINATE with the advantage of a much shorter half-life when compared with etretinate.
ACLIDINIUM BROMIDE
CAS:320345-99-1
Formula: C26H30NO4S2Br
T2555
99%
Aclidinium Bromide inhibits human muscarinic AChR M1, M2, M3, M4 and M5 with Ki of 0.1 nM, 0.14 nM, 0.14 nM, 0.21 nM and 0.16 nM, respectively.
ACOTIAMIDE HYDROCHLORIDE
CAS:773092-05-0
Formula: C21H37ClN4O8S
T2319
98%
Acotiamide Hydrochloride is the hydrochloride salt form of acotiamide, a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamide exerts its effect has yet to be fully elucidated, this agent
ACRIDINE
CAS:260-94-6
Formula: C13H9N
T0602
100%
fluorescent pH indicator
ACTARIT
CAS:18699-02-0
Formula: C10H11NO3
T0310
97%
Actarit is an anti-inflammatory drug developed in Japan for use in rheumatoid arthritis
ACTIDIONE
CAS:66-81-9
Formula: C15H23NO4
T1225
98%
Antibiotic substance isolated from streptomycin-producing strains of Streptomyces griseus. It acts by inhibiting elongation during protein synthesis.
ACTRIOL
CAS:547-81-9
Formula: C18H24O3
T1683
98%
n/a
ACY-1215
CAS:1316214-52-4
Formula: C24H27N5O3
T2489
99%
Rocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM in a cell-free assay. It is >10-fold more selective for HDAC6 than HDAC1/2/3 (class I HDACs) with slight activity against HDAC8, minimal activity against HDAC4/5/7/9/11, Sirtuin1, an
ACYCLOVIR
CAS:59277-89-3
Formula: C8H11N5O3
T1454
99%
Acyclovir is a synthetic nucleoside analogue active against herpesviruses. It is a guanosine analogue antiviral drug. Aciclovir differs from previous nucleoside analogues in that it contains only a partial nucleoside structure: the sugar ring is replaced
ADAPALENE
CAS:106685-40-9
Formula: C28H28O3
T1093
99%
Adapalene is a topical retinoid primarily used in the treatment of acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions. It is currently marketed by Galderma under the trade names Differin in some countries, and Ad
ADEFOVIR DIPIVOXIL
CAS:142340-99-6
Formula: C20H32N5O8P
T1675
98%
Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adef
ADENINE
CAS:73-24-5
Formula: C5H5N5
T0064
98%
Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry. Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry including cellular respiration, in the form of both the energy-rich adenosine
ADENINE HCL
CAS:2922-28-3
Formula: C5H5N5.HCl
T6225
98%
Adenine HCl is a hydrochloride salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry.
ADENOSINE
CAS:58-61-7
Formula: C10H13N5O4
T0853
98%
Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a -N9-glycosidic bond.
ADENOSINE 5'-MONOPHOSPHATE
CAS:61-19-8
Formula: C10H14N5O7P
T2133
98%
Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
ADENOSINE 5'-MONOPHOSPHATE MONOHYDRATE
CAS:18422-05-4
Formula: C10H14N5O7PH2O
T0853L
96%
Adenosine monophosphate (AMP), also known as 5'-adenylic acid, is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid and the nucleoside adenosine. AMP consists of a phosphate group, the sugar ribose, and the nucleobase adenin
ADENOSINE DISODIUM TRIPHOSPHATE
CAS:34369-07-8
Formula: C10H14N5Na2O13P3
T2812
99%
Adenosine triphosphate (ATP) is a nucleoside triphosphate used in cells as a coenzyme often called the molecular unit of currency of intracellular energy transfer.
ADIPHENINE HYDROCHLORIDE
CAS:50-42-0
Formula: C20H25NO2HCl
T0072
98%
Adiphenine hydrochloride is a nicotinic receptor inhibitor, used as an antispasmodic drug.
ADIPIC ACID
CAS:124-04-9
Formula: C6H10O4
T2228
99%
From an industrial perspective, it is the most important dicarboxylic acid, mainly as a precursor for the production of nylon.
ADIPORON
CAS:924416-43-3
Formula: C27H28N2O3
T2257
98%
AdipoRon is a novel, and orally bioavailable adiponectin receptor agonist with KD of 1.8 and 3.1 M for AdipoR1 and AdipoR2, respectively.
ADJUDIN (AF-2364)
CAS:252025-52-8
Formula: C15H12Cl2N4O
T2498
98%
Adjudin (AF-2364) is a drug which is under development as a potential non-hormonal male contraceptive drug, which acts by blocking the production of sperm in the testes, but without affecting testosterone production.
ADL5859 HCL
CAS:850173-95-4
Formula: C24H28N2O3HCl
T6175
98%
ADL5859 HCl is a d-opioid receptor agonist with Ki of 0.8 nM, selectivity against opioid receptor ?, , and weak inhibitory activity at the hERG channel. Phase 2.
ADP
CAS:58-64-0
Formula: C10H15N5O10P2
T1723
95%+
Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
ADRENALONE HYDROCHLORIDE
CAS:62-13-5
Formula: C9H11NO3HClxH2O
T0948
98%
Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic, mainly acts on alpha-1 adrenergic receptors.
ADRENOSTERONE
CAS:382-45-6
Formula: C19H24O3
T2207
98%
Adrenosterone is a steroid hormone with weak androgenic effect. It was first isolated in 1936 from the adrenal cortex by Tadeus Reichstein at the Pharmaceutical Institute in the University of Basel. Originally, adrenosterone was called Reichstein's substa
ADX-47273
CAS:851881-60-2
Formula: C20H17F2N3O2
T2053
98%
ADX47273 is a potent and specific mGlu5 positive allosteric modulator(PAM) with EC50 of 0.17 M, showing no activity at other mGlu subtypes.
AEBSF HCL
CAS:30827-99-7
Formula: C8H11ClFNO2S
T6370
98%
AEBSF HCl is a broad spectrum, irreversible serine protease inhibitor.
AEE788
CAS:497839-62-0
Formula: C27H32N6
T2116
98%
AEE788 (NVP-AEE788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt-1, does not inhibit Ins-R, IGF-1R, PKCa and CDK1. Phase 1/2.
AF 353
CAS:865305-30-2
Formula: C14H17IN4O2
T2087
98%
AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist, inhibits human and rat P2X3 (pIC50= 8.0).
AFATINIB (BIBW2992)
CAS:439081-18-2
Formula: C24H25ClFN5O3
T2303
98%
Afatinib is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic activity. Upon administration, afatinib selectively and irrever
AFATINIB DIMALEATE
CAS:850140-73-7
Formula: C32H33ClFN5O11
T1773
98%
Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant.
AFOBAZOLE
CAS:173352-21-1
Formula: C15H21N3O2S
T1864
98%
Afobazole (CM346) is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions.
AFURESERTIB
CAS:1047644-62-1
Formula: C18H17Cl2FN4OS
T1911
98%
Afuresertib (GSK2110183) is a potent pan-AKT inhibitor that demonstrated synergy with bortezomib in preclinical models of multiple myeloma (MM).
AG 18
CAS:118409-57-7
Formula: C10H6N2O2
T2063
98%
AG-18(RG-50810; Tyrphostin A23) inhibits EGFR with IC50 of 35 M.
AG-14361
CAS:328543-09-5
Formula: C19H20N4O
T6339
98%
AG14361 is a potent inhibitor of PARP1 with Ki of <5 nM. It is at least 1000-fold more potent than the benzamides.
AG-1478
CAS:153436-53-4
Formula: C16H14ClN3O2
T2047
98%
AG-1478 (Tyrphostin AG-1478) is a selective EGFR inhibitor with IC50 of 3 nM in cell-free assays, almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR.
AG-1557
CAS:189290-58-2
Formula: C16H14IN3O2
T2034
98%
Detail unknown.
AG-337;NOLATREXED 2HYDROCHLORIDE
CAS:152946-68-4
Formula: C14H14Cl2N4OS
T2627
100%
Nolatrexed Dihydrochloride is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymid
AG-490
CAS:133550-30-8
Formula: C17H14N2O3
T2600
99%
AG-490 (Tyrphostin AG 490) is an inhibitor of EGFR with IC50 of 0.1 M, 135-fold more selective for EGFR versus ErbB2, also inhibits JAK2 with no activity to Lck, Lyn, Btk, Syk and Src.
AGI-5198
CAS:1355326-35-0
Formula: C27H31FN4O2
T2104
98%
AGI-5198 is the first highly potent and selective inhibitor of IDH1 R132H/R132C mutants with IC50 of 0.07 M/0.16 M.
AGI-6780
CAS:1432660-47-3
Formula: C21H18F3N3O3S2
T1809
98%
AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant with IC50 of 23 nM.
AGIPNON
CAS:64-65-3
Formula: C8H13NO2
T1396
98%
A CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose.
AGK2
CAS:304896-28-4
Formula: C23H13Cl2N3O2
T6371
98%
AGK2 is a potent, and selective SIRT2 inhibitor with IC50 of 3.5 M.
AGOMELATINE
CAS:138112-76-2
Formula: C15H17NO2
T1445
99%
Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Agomelatine was discovered and developed by the
AHAS INHIBITOR BTB06584
CAS:219793-45-0
Formula: C19H12ClNO6S
T1940
98%
AHAS inhibitor is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug target against Mycobacterium tuberculosis (MTB).
AJMALINE`AICAR
CAS:2627-69-2
Formula: C9H14N4O5
T1477
99%
Acadesine (AICA-riboside) is a purine nucleoside analog with anti-ischemic properties that is currently being studied (Phase 3) for the prevention of adverse cardiovascular outcomes in patients undergoing coronary artery bypass graft (CABG) surgery. It is
AKLOMIDE
CAS:3011-89-0
Formula: C7H5ClN2O3
T0390
98%
Aklomide, known as a kind of Benzamide compounds, has antimicrobial and antioxidant activity.
AL082D06
CAS:256925-03-8
Formula: C23H24ClN3O2
T1749
98%
AL 082D06(D-06) is the first selective, nonsteroidal glucocorticoid receptor (GR) antagonist with Ki of 210 nM, exhibits excellent selectivity against AR, PR, MR and ER(Ki > 10 uM).
ALANTOLACTONE
CAS:546-43-0
Formula: C15H20O2
T2896
98%
Extracted?from?Inula helenium L. roots,Inula grandis chrenk leaves;Store?the?product?in?sealed,?cool?and?dry?condition
ALARELIN ACETATE
CAS:79561-22-1
Formula: C56H78N16O12
T1494
98%
Alarelin acetate is a synthetic GnRH agonist. Alarelin is found in higher amounts than that of LH-RH in rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in ovulation inductions.
ALBENDAZOLE
CAS:54965-21-8
Formula: C12H15N3O2S
T1152
98%
Albendazole(Albenza) is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations. Albendazole causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the co
ALCAFTADINE
CAS:147084-10-4
Formula: C19H21N3O
T2533
98%
Alcaftadine(R89674) is a H1 histamine receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis.
ALDA-1
CAS:349438-38-6
Formula: C15H11Cl2NO3
T2662
100%
Alda-1 is an ALDH2 agonist, cell-permeable activator of both the wild-type ALDH2*1 and the asian E487K mutant ALDH2*2 forms of mitochondrial aldehyde dehydrogenase 2 (mtALDH2).
ALEURITIC ACID
CAS:533-87-9
Formula: C16H32O5
T2886
95%
Aleuritic acid, or a-aleuritic acid, is a major ingredient in shellac, constituting about 35% of it. It is used as a starting material in the perfume industry for the preparation of musk aroma.
ALFACALCIDOL
CAS:41294-56-8
Formula: C27H44O2
T6374
98%
Alfacalcidol is a non-selective VDR activator medication.
ALFUZOSIN HYDROCHLORIDE
CAS:81403-68-1
Formula: C19H27N5O4HCl
T0091
98%
Alfuzosin(Uroxatral) is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH). It works by relaxing the muscles in the prostate and bladder neck, making it easier to urinate.
ALISERTIB
CAS:1028486-01-2
Formula: C27H20ClFN4O4
T2241
98%
Alisertib is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Alisertib binds to and inhibits Aurora A kinase, which may resu
ALISKIREN HEMIFUMARATE
CAS:173334-58-2
Formula: C30H53N3O61/2C4H4O4
T1520
96%
Aliskiren hemifumarate is a direct renin inhibitor
ALIZAPRIDE HYDROCHLORIDE
CAS:59338-87-3
Formula: C16H21N5O2HCl
T2574
99%
Alizapride hydrochloride is a dopamine receptor antagonist used for the theropy of nausea and vomiting.
ALIZARIN
CAS:72-48-0
Formula: C14H8O4
T2949
97%
Alizarin or 1,2-dihydroxyanthraquinoneis an organic compound that has been used throughout history as a prominent red dye, principally for dyeing textile fabrics. Historically it was derived from the roots of plants of the madder genus. In 1869, it became
ALK INHIBITOR 2
CAS:761438-38-4
Formula: C23H28ClN7O3S
T3041
100%
ALK inhibitor 2 is a novel and selective inhibitor for the ALK kinase.
ALLANTOIN
CAS:97-59-6
Formula: C4H6N4O3
T0925
98%
Extracted from Dioscorea opposite Thunb
ALLICIN
CAS:539-86-6
Formula: C6H10OS2
T3123
98%
Allicin is an organosulfur compound obtained from garlic, a species in the family Alliaceae.
ALLOPURINOL
CAS:315-30-0
Formula: C5H4N4O
T0692
98%
An anti-urolithic Xanthine oxidase inhibitor that decreases uric acid production and is used in treatment of hyperuricemia and chronic gout.
ALLOPURINOL SODIUM
CAS:17795-21-0
Formula: C5H4N4NaO
T6376
98%
Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.820.12 M.
ALLOTROPAL
CAS:77-75-8
Formula: C6H10O
T0387
98%
3-Methyl-1-pentyn-3-ol has the potencial proterty to inhibit CYP3A.
ALLYL ISOTHIOCYANATE
CAS:57-06-7
Formula: C4H5NS
T3087
Allyl isothiocyanate, inhibited is a colorless to pale-yellow oily liquid with an irritating odor.
ALLYLESTRENOL
CAS:432-60-0
Formula: C21H32O
T2559
98%
Allylestrenol is a synthetic steroid with progestational activity.
ALLYLTHIOUREA
CAS:109-57-9
Formula: C4H8N2S
T0418
98%
Allylthiourea is a metabolic inhibitor that selective inhibits ammonia oxidation.
ALMOREXANT
CAS:871224-64-5
Formula: C29H31F3N2O3
T2613
98%
Almorexant(ACT078573) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively.
ALMOREXANT HCL
CAS:913358-93-7
Formula: C29H32ClF3N2O3
T6155
98%
Almorexant HCl is an orally active, dual orexin receptor antagonist with IC50 of 6.6 nM and 3.4 nM for OX1 and OX2 receptor, respectively. Phase 3.
ALMOTRIPTAN MALATE
CAS:181183-52-8
Formula: C17H25N3O2SC4H6O5
T2317
98%
Almotriptan Malate is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults.
ALODAN
CAS:2550-75-6
Formula: C9H6Cl8
T1380
100%
Alodan is an organic chloride insecticide
ALOE EMODIN
CAS:481-72-1
Formula: C15H10O5
T2843
100%
Aloe-emodin is an interferon-inducing agent with IC50 of about 1 g/mL for JEV and of about 0.33 g/mL for EV71.
ALOGLIPTIN
CAS:850649-61-5
Formula: C18H21N5O2
T6192
98%
Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.
ALOGLIPTIN BENZOATE
CAS:850649-62-6
Formula: C25H27N5O4
T2401
98%
Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9.
ALOIN
CAS:1415-73-2
Formula: C21H22O9
T2742
98%
Aloin, a natural anthracycline from Aloe vera, is a tyrosinase inhibitor
ALOSETRON HYDROCHLORIDE
CAS:122852-69-1
Formula: C17H19ClN4O
T2525
98%
Alosetron hydrochloride is a Serotonin 5HT3-receptor antagonist that is used in treatment of irritable bowel syndrome.
ALOXISTATIN
CAS:88321-09-9
Formula: C17H30N2O5
T6040
98%
Aloxistatin is an irreversible and membrane-permeable cysteine protease inhibitor.
ALPHA-BOSWELLIC ACID
CAS:471-66-9
Formula: C30H48O3
T3248
N/A
Boswellic acids?are a series of pentacyclic?triterpene?molecules that are produced by plants in the genusBoswellia.
ALPHA-LIPOIC ACID
CAS:1077-28-7
Formula: C8H14O2S2
T0200
98%
THIOOCTIC ACID, a natural product, is reported to have antioxidative property.
ALPHALIPOIC ACID
CAS:62-46-4
Formula: C8H13O2S2
T2930
98%
Extracted from potato, spinach, broccoli, tomato, carrot,hepar;Store the product in sealed, cool and dry condition
ALTIRATINIB
CAS:1345847-93-9
Formula: C26H21F3N4O4
T2054
98%
Altiratinib(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro.
ALTRENOGEST
CAS:850-52-2
Formula: C21H26O2
T0870
98%
Altrenogest is a progestogen structurally related to veterinary steroid trenbolone.
ALTRETAMINE
CAS:645-05-6
Formula: C9H18N6
T1241
98%
Altretamine is an Alkylating Drug. The mechanism of action of altretamine is as an Alkylating Activity.
ALVELESTAT
CAS:848141-11-7
Formula: C25H22F3N5O4S
T3107
98%
Alvelestat (AZD9668) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.4 nM, at least 600-fold more selective over other serine proteases. Phase 2.
ALVERINE CITRATE
CAS:5560-59-8
Formula: C26H35NO7
T0428
99%
Alverine citrate is a drug used for functional gastrointestinal disorders.
ALVIMOPAN
CAS:156053-89-3
Formula: C25H32N2O4
T1242
98%
Alvimopan(LY 246736; ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery.
AM095
CAS:1345614-59-6
Formula: C27H23N2NaO5
T2000
98%
AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 _mu_M for recombinant human or mouse LPA1 respectively.
AM251
CAS:183232-66-8
Formula: C22H21Cl2IN4O
T1915
98%
AM251 block the inhibitory effects of endocannabinoids and synthetic cannabinoid agonists on transmitter release through an action at presynaptic cannabinoid 1 receptors in brain.
AM281
CAS:202463-68-1
Formula: C21H19Cl2IN4O2
T2264
98%
Cannabinoid antagonist AM 281 reduces mortality rate and neurologic dysfunction after cecal ligation and puncture in rats.
AMANTADINE HYDROCHLORIDE
CAS:665-66-7
Formula: C10H18ClN
T1406
98%
An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are
AMBRISENTAN
CAS:177036-94-1
Formula: C22H22N2O4
T1655
98%
Ambrisentan is an Endothelin Receptor Antagonist. The mechanism of action of ambrisentan is as an Endothelin Receptor Antagonist.
AMBROXOL
CAS:18683-91-5
Formula: C13H18Br2N2O
T0920
99%
Ambroxol is indicated as secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport. It promotes mucus clearance, facilitates expectoration and eases productive cough, allowing patients to breat
AMBROXOL HCL
CAS:23828-92-4
Formula: C13H18Br2N2OHCl
T6234
98%
AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 M and 22.5 M for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 M. Phase 3.
AMCINONIDE
CAS:51022-69-6
Formula: C28H35FO7
T0261
98%
Amcinonide is a corticosteroid.
AMFENAC SODIUM MONOHYDRATE
CAS:61618-27-7
Formula: C15H12NO3H2ONa
T1720
98%
Amfenac Sodium monohydrate is a non-steroidal analgesic anti-inflammatory drug with acetic acid moiety.
AMFEPRAMONE HYDROCHLORIDE
CAS:134-80-5
Formula: C13H20ClNO
T1450
97%
A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension.
AMG-208
CAS:1002304-34-8
Formula: C22H17N5O2
T6260
98%
AMG 208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.
AMG-337
CAS:1173699-31-4
Formula: C23H22FN7O3
T3209
98%
AMG-337 is a potent and highly selective small molecule ATP-competitive MET kinase inhibitor. AMG 337 inhibits MET kinase activity with an IC50 of < 5nM in enzymatic assays.
AMG-458
CAS:913376-83-7
Formula: C30H29N5O5
T6378
98%
AMG 458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells.
AMG-517
CAS:659730-32-2
Formula: C20H13F3N4O2S
T6379
98%
AMG 517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM.
AMG-900
CAS:945595-80-2
Formula: C28H21N7OS
T6380
98%
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM. It is >10-fold selective for Aurora kinases than p38a, Tyk2, JNK2, Met and Tie2. Phase 1.
AMI-1
CAS:20324-87-2
Formula: C21H14N2Na2O9S2
T2352
98%
AMI-1 is a potent and specific Histone Methyltransferase (HMT) inhibitor with IC50 of 3.0 M and 8.8 M for yeast Hmt1p and human PRMT1, respectively.
AMI-5
CAS:17372-87-1
Formula: C20H6Br4Na2O5
T2178
80%
Eosin yellowish is a versatile red dye used in cosmetics, pharmaceuticals, textiles, etc., and as tissue stain, vital stain, and counterstain with HEMATOXYLIN. It is also used in special culture media.
AMIDRINE
CAS:543-82-8
Formula: C8H19N
T0043
99%
Octodrine is a stimulant drug whose pharmacology was briefly studied in the early 1950s. A platinum complex form of the molecule was also investigated as a possible anti-tumor drug
AMIFOSTINE
CAS:20537-88-6
Formula: C5H15N2O3PS
T3289
98%
Amifostine?is a cytoprotective adjuvant used in cancerchemotherapy?and?radiotherapyinvolving?DNA-binding chemotherapeutic agents.
AMIKACIN
CAS:37517-28-5
Formula: C22H43N5O13
T1013
98%
A broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and oto-toxic like the other aminoglycoside antibiotics.
AMIKACIN DISULFATE
CAS:39831-55-5
Formula: C22H43N5O132H2O4S
T6382
98%
Amikacin sulfate binds to 16S rRNA (bacterial 30S ribosome), causing misreading of mRNA and supressing proteins synthesis.
AMIKACIN SULFATE SALT
CAS:149022-22-0
Formula: C22H45N5O17S
T3125
98%
A broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and oto-toxic like the other aminoglycoside antibiotics.
AMILORIDE HYDROCHLORIDE
CAS:2016-88-8
Formula: C6H9Cl2N7O
T0175
98%
A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Ne
AMILORIDE HYDROCHLORIDE DIHYDRATE
CAS:17440-83-4
Formula: C6H8ClN7OHCl2H2O
T0175L
98%
A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Ne
AMINACRINE
CAS:90-45-9
Formula: C13H10N2
T0289
100%
A highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It is also used as an intracellular pH indicator.
AMINOGLUTETHIMIDE
CAS:125-84-8
Formula: C13H16N2O2
T1103
99%
Aminoglutethimide is an aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
AMINOGUANIDINE HYDROCHLORIDE
CAS:1937-19-5
Formula: CH6N4HCl
T0358
98%
Amodiaquine, a 4-aminoquinoline compound related to chloroquine, is used as an antimalarial and anti-inflammatory agent.
AMINOPAR
CAS:65-49-6
Formula: C7H7NO3
T1296
85%
4-aminosalicylic acid, commonly known as PAS, is an antibiotic used to treat tuberculosis.
AMINOPHYLLINE
CAS:317-34-0
Formula: 2C7H8O2C2H8N2
T1681
98%
Aminophylline is a drug combination that contains THEOPHYLLINE and ethylenediamine. It is more soluble in water than theophylline but has similar pharmacologic actions. It's most common use is in bronchial asthma, but it has been investigated for several
AMINOTHIAZOLE
CAS:96-50-4
Formula: C3H4N2S
T0495
98%
Aminothiazole can be used as a thyroid inhibitor and it has antibacterial activity.
AMIODARONE HYDROCHLORIDE
CAS:19774-82-4
Formula: C25H29I2NO3HCl
T1496
98%
An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
AMISULPRIDE
CAS:71675-85-9
Formula: C17H27N3O4S
T0811
99%
Amisulpride (trade name Solian) is an antipsychotic drug sold by Sanofi-Aventis. It is not approved for use in the United States, but is approved for use in Europe and Australia for the treatment of psychoses and schizophrenia. Additionally, it is approve
AMITIFADINE HYDROCHLORIDE
CAS:410074-74-7
Formula: C11H12Cl3N
T2092
98%
Amitifadine hydrochloride is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). Ki values for SERT/NET/ DAT are 99/262/213 nM. The IC50 values for serotonin, norepinephrine and dopamine reuptake are 12/23/96
AMITRAZ
CAS:33089-61-1
Formula: C19H23N3
T1632
97%
Amitraz is a non-systemic acaricide and insecticide.
AMITRIPTYLINE HYDROCHLORIDE
CAS:549-18-8
Formula: C20H24ClN
T0678
98%
Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagoniz
AMLEXANOX
CAS:68302-57-8
Formula: C15H14N2O4
T1639
98%
Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent aphthous ulcer (RAU) is the most preva
AMLODIPINE
CAS:88150-42-9
Formula: C26H31ClN2O8S
T1385
99%
Amlodipine is a long-acting calcium channel blocker. Amlodipine is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the movement of calcium ions into vascular smooth muscle cells and cardiac muscle cells.
AMLODIPINE BESYLATE
CAS:111470-99-6
Formula: C26H31ClN2O8S
T0231
99%
Amlodipine Besylate is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain.
AMMONIUM GLYCYRRHIZINATE
CAS:1407-03-0
Formula: C42H62O16NH3
T6384
98%
Ammonium Glycyrrhizinate inhibits growth and cytopathology of several unrelated DNA and RNA viruses.
AMODIAQUIN DIHYDROCHLORIDE DIHYDRATE
CAS:6398-98-7
Formula: C20H24Cl3N3O
T0381
98%
A 4-aminoquinoline compound with anti-inflammatory properties.
AMONAFIDE
CAS:69408-81-7
Formula: C16H17N3O2
T6336
98%
Amonafide produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage. Phase 3.
AMOROLFINE HYDROCHLORIDE
CAS:78613-38-4
Formula: C21H36ClNO
T0187
99%
Amorolfine Hydrochloride is an antifungal reagent. It exerts the antifungal activity by selectively blocking two steps in the pathway of ergosterol synthesis, and eventually damaging the structure and function of fungal cell membrane. Amorolfine (or amoro
AMOXAPINE
CAS:14028-44-5
Formula: C17H16ClN3O
T1568
98%
Amoxapine is the N-demethylated derivative of the antipsychotic agent LOXAPINE that works by blocking the reuptake of norepinephrine, serotonin, or both. It also blocks dopamine receptors.
AMOXICILLIN
CAS:26787-78-0
Formula: C16H19N3O5S
T1005
potency:900g/mg
A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.
AMOXICILLIN SODIUM
CAS:34642-77-8
Formula: C16H18N3O5SNa
T6385
98%
Amoxicillin Sodium is a moderate- spectrum, bacteriolytic, -lactam antibiotic.
AMOXICILLIN TRIHYDRATE
CAS:61336-70-7
Formula: C16H19N3O5S3(H2O)
T1005L
99%
A broad-spectrum semisynthetic antibiotic similar to AMPICILLIN except that its resistance to gastric acid permits higher serum levels with oral administration.
AMPALEX
CAS:154235-83-3
Formula: C14H15N3O
T1884
98%
Ampalex (Ampakine CX516; CX516; BDP 12) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI).
AMPHOTERICIN B
CAS:1397-89-3
Formula: C47H73NO17
T1067
>750ug/mg
Amphotericin b is a Lipid-based Polyene Antifungal and Polyene Antifungal. The chemical classification of amphotericin b is Polyenes.
AMPICILLIN
CAS:69-53-4
Formula: C16H19N3O4S
T0814L
98%
Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
AMPICILLIN SODIUM
CAS:69-52-3
Formula: C16H18N3NaO4S
T6386
98%
Ampicillin is a beta-lactam antibiotic that is part of the aminopenicillin family.
AMPICILLIN TRIHYDRATE
CAS:7177-48-2
Formula: C16H19N3O4S3H2O
T0814
Ampicillin Trihydrate is a -lactam antibiotic, which inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane
AMPIROXICAM
CAS:99464-64-9
Formula: C20H21N3O7S
T6387
98%
Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.
AMPRENAVIR
CAS:161814-49-9
Formula: C25H35N3O6S
T6388
98%
Amprenavir is a potent PXR-selective agonist, and an HIV protease inhibitor, used to treat HIV.
AMPROLIUM
CAS:121-25-5
Formula: C14H19N4.Cl
T0872
99%
Veterinary coccidiostat that interferes with thiamine metabolism. It may cause thiamine deficiency.
AMPROLIUM HYDROCHLORIDE
CAS:137-88-2
Formula: C14H19ClN4HCl
T0872L
98%
Amprolium chloride is a thiamin antagonist, which prevents carbohydrate synthesis by blocking thiamine uptake.
AMRINONE
CAS:60719-84-8
Formula: C10H9N3O
T1265
98%
A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase 3 inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.
AMSACRINE
CAS:51264-14-3
Formula: C21H19N3O3S
T1206
99%
Aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with ot
AMUVATINIB
CAS:850879-09-3
Formula: C23H21N5O3S
T2516
98%
Amuvatinib (MP-470) is a potent and multi-targeted inhibitor of c-Kit, PDGFRa and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. Phase 2.
AMYLENHYDRATE
CAS:75-85-4
Formula: C5H12O
T0761
99%
a branched pentanol used primarily as a pharmaceutical or pigment solvent. It remains liquid at room temperature making it a useful alternative to tert-butyl alcohol. It is a colorless liquid with a pungent odor of camphor which is miscibile with both wat
ANA-12
CAS:219766-25-3
Formula: C22H21N3O3S
T2359
98%
ANA-12 is a selective TrkB antagonist with Kd of 10 nM and 12 M for the high and low affinity sites, respectively.
ANACARDIC ACID
CAS:16611-84-0
Formula: C22H36O3
T6389
98%
Anacardic Acid is a potent inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases, which also has antibacterial activity, antimicrobial activity, prostaglandin synthase inhibition, and tyrosinase and lipoxygenase inhibition.
ANACETRAPIB
CAS:875446-37-0
Formula: C30H25F10NO3
T1928
98%
Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Phase 3.
ANAGRELIDE
CAS:68475-42-3
Formula: C10H7Cl2N3OHCl
T0160
99%
Anagrelide is a Platelet-reducing Agent. The mechanism of action of anagrelide is as a Phosphodiesterase 3 Inhibitor.
ANAGRELIDE HCL
CAS:58579-51-4
Formula: C10H7Cl2N3OHCl
T6390
98%
Anagrelide is a drug used for the treatment of essential thrombocytosis.
ANALGIN
CAS:5907-38-0
Formula: C13H16N3NaO4S
T1191
99%
A drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of AMINOPYRINE. Because of the risk of serious adverse effects its use is justified only in serious situations where no alternative is available or suitab
ANASTROZOLE
CAS:120511-73-1
Formula: C17H19N5
T0393
98%
Anastrozole is a drug indicated in the treatment of breast cancer in post-menopausal women. It is used both in adjuvant therapy (i.e. following surgery) and in metastatic breast cancer. It decreases the amount of estrogens that the body makes. Anastrozole
ANDARINE
CAS:401900-40-1
Formula: C19H18F3N3O6
T2108
98%
Andarine is a selective non-steroidal androgen receptor (AR) agonist with Ki of 4 nM, tissue-selective for anabolic organs. Phase 3.
ANDROGRAPHOLIDE
CAS:5508-58-7
Formula: C20H30O5
T2898
98%
Inhibitor of NF-?B signaling; also attenuates concanavaline-induced IFN? production in murine T cells (IC50 = 1.7 M). Blocks androgen receptor (AR) expression in AR-expressing C4-2 cells. Activates Nrf2 in BEAS-2B cells in response to cigarette smoke ext
ANETHOLE
CAS:104-46-1
Formula: C10H12O
T0014
99%
Extracted from Foeniculum vulgare fruit;Store the product in sealed, cool and dry condition
ANETHOLE TRITHIONE
CAS:532-11-6
Formula: C10H8OS3
T1285
98%
Choleretic used to allay dry mouth and constipation due to tranquilizers.
ANGELICIN
CAS:523-50-2
Formula: C11H6O3
T2875
99%+
Extracted from Psoralea corylifolia L.;Suitability:Ethanol,chloroform;Store the product in sealed,cool and dry condition
ANIDULAFUNGIN (LY303366)
CAS:166663-25-8
Formula: C58H73N7O17
T6088
98%
Anidulafungin (LY303366), an echinocandin derivative, inhibits glucan synthase activity, used as an antifungal drug.
ANIRACETAM
CAS:72432-10-1
Formula: C12H13NO3
T0333
99%
Compound with anti-depressive properties used as a mental performance enhancer.
ANISODAMINE
CAS:17659-49-3
Formula: C17H23NO4
T0970
98%
Anisodamine, also known as 7-hydroxyhyoscyamine, is an anticholinergic and a1-adrenergic receptor antagonist used in the treatment of acute circulatory shock in China. It is also a naturally occurring tropane alkaloid found in some plants of the Solanace
ANITAROL
CAS:642-71-7
Formula: C9H12O4
T2936
97%
n/a
ANOVIGAM
CAS:938-73-8
Formula: C9H11NO2
T0058
97%
Ethenzamide is a common analgesic and anti-inflammatory drug that is used for the relief of fever, headaches, and other minor aches and pains.
ANSAMITOCIN P-3
CAS:66547-09-9
Formula: C32H43ClN2O9
T1910
98%
Ansamitocin P-3 is a maytansine analog which displays potent cytotoxicity against the human solid tumor cell lines A-549 and HT-29; Antibody drug conjugate cytotoxin.
ANTAZOLINE HYDROCHLORIDE
CAS:2508-72-7
Formula: C17H19N3HCl
T0092
98%
Antazoline hydrochloride is a first generation antihistamine, binding to the histamine H1 receptor and blocking the action of endogenous histamine.
ANTIMONYL POTASSIUM TARTRATE TRIHYDRATE
CAS:28300-74-5
Formula: C8H4K2O12Sb23H2O
T0831
99%
Antimony potassium tartrate, also known as potassium antimonyl tartrate, potassium antimontarterate, or emetic tartar, has the formula K2Sb2(C4H2O6)2 and is the double salt of potassium and antimony of tartaric acid. The compound has long been known as a
ANTIMYCIN A
CAS:1397-94-0
Formula: C27H38N2O9
T1712
95%
Fintrol is an antibiotic substance produced by Streptomyces species. It inhibits mitochondrial respiration and may deplete cellular levels of ATP. Antimycin A1 has been used as a fungicide, insecticide, and miticide. (From Merck Index, 12th ed)
ANTIPYRINE
CAS:60-80-0
Formula: C11H12N2O
T0734
98%
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. .
AP26113
CAS:1197958-12-5
Formula: C26H34ClN6O2P
T3059
98%
AP26113 is a potent ALK inhibitor with IC50 of 0.62 nM in a cell-free assay, demonstrated ability overcome Crizotinib resistance mediated by a L1196M mutation. Phase 2.
APATINIB
CAS:811803-05-1
Formula: C25H27N5O4S
T2582
100%
Apatinib is an orally bioavailable, selective VEGFR2 inhibitor with IC50 of 1 nM.
APD597
CAS:897732-93-3
Formula: C21H29N5O6S
T3176
98%
APD597 is a GPR119 agonist intended for the treatment of type 2 diabetes, with EC50 of 46 nM for hGPR119.
APD668
CAS:832714-46-2
Formula: C21H24FN5O5S
T2088
98%
APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119 respectively.
APIGENIN
CAS:520-36-5
Formula: C15H10O5
T2175
100%
Apigenin is a potent P450 inhibitor for CYP2C9 with Ki of 2 M.
APILIMOD
CAS:541550-19-0
Formula: C23H26N6O2
T2018
98%
Apilimod inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.
APITOLISIB (GDC-0980, RG7422)
CAS:1032754-93-0
Formula: C23H30N8O3S
T1916
98%
Apitolisib (GDC-0980, RG7422) is a potent, class I PI3K inhibitor for PI3Ka//d/? with IC50 of 5 nM/27 nM/7 nM/14 nM in cell-free assays, respectively. Also a mTOR inhibitor with Ki of 17 nM in a cell-free assay, and highly selective versus other PIKK fam
APIXABAN
CAS:503612-47-3
Formula: C25H25N5O4
T1736
98%
Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively.
APOCYNIN
CAS:498-02-2
Formula: C9H10O3
T6391
98%
Apocynin is a selective NADPH-oxidase inhibitor with IC50 of 10 M.
APOPTOSIS ACTIVATOR 2
CAS:79183-19-0
Formula: C15H9Cl2NO2
T1772
98%
Apoptosis Activator 2 is a potent apoptosis activator; increases procaspase-9 processing and subsequent caspase-3 activation.
APRAMYCIN SULFATE
CAS:65710-07-8
Formula: C21H43N5O15S
T1084
95%
Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria. Apramycin is a structurally unique antibiotic that contains a bicyclic sugar moiety and a monosubstituted deoxystreptamine. It is not approved for
APREMILAST
CAS:608141-41-9
Formula: C22H24N2O7S
T2923
98%
Apremilast (CC-10004) is a potent and orally active PDE4 and TNF-a inhibitor with IC50 of 74 nM and 77 nM, respectively.
APREPITANT
CAS:170729-80-3
Formula: C23H21F7N4O3
T1743
98%
Aprepitant is a potent and selective neurokinin-1 receptor antagonist.
APY0201
CAS:1232221-74-7
Formula: C23H23N7O
T2061
98%
APY0201 is a potent, highly selective, ATP-competitive PIKfyve inhibitor (IC50=5.2 nM) that interrupts the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3,5)P2; a unique small molecular IL-12/23 production inhibitor.
AR-42
CAS:935881-37-1
Formula: C18H20N2O3
T6392
98%
AR-42 is an HDAC inhibitor with IC50 of 30 nM. Phase 1.
AR-A014418
CAS:487021-52-3
Formula: C12H12N4O4S
T1881
98%
AR-A014418 is an ATP-competitive, and selective GSK3 inhibitor with IC50 and Ki of 104 nM and 38 nM in cell-free assays, without significant inhibition on 26 other kinases tested.
ARBIDOL HYDROCHLORIDE
CAS:131707-23-8
Formula: C22H25BrN2O3SHCl
T0104
98%
Arbidol hydrochloride is an antiviral treatment for influenza infection.
ARBUTIN
CAS:497-76-7
Formula: C12H16O7
T0473
98%
Arbutin is glucosylated hydroquinone, and may carry similar cancer risks, although there are also claims that arbutin reduces cancer risk. It prevents the formation of melanin.
ARCTIGENIN
CAS:7770-78-7
Formula: C21H24O6
T2957
98%
Arctigenin, the main effective constituent of Arctium lappa L. fruit, has previously been proven to dramatically attenuate dextran sulfate sodium (DSS)-induced colitis in mice, a frequently used animal model of inflammatory bowel disease (IBD).
ARCTIIN
CAS:20362-31-6
Formula: C27H34O11
T2766
98%
(-)-Arctiin is a lignan derivative with antitumor activities acting as a potent inhibitor of HIV-I integrase and DNA topoisomerase II. (-)-Arctiin down-regulates anti-apoptotic protein Bcl-XL.
ARECOLINE HYDROBROMIDE
CAS:300-08-3
Formula: C8H13NO2HBr
T2198
98%
Arecoline Hydrobromide is a muscarinic acetylcholine receptor agonist.
ARGATROBAN
CAS:74863-84-6
Formula: C23H36N6O5S
T0155
99%
Argatroban is a direct, selective thrombin inhibitor. The American College of Cardiologists (ACC) recommend using bivalirudin or argatroban in patients who have had, or at risk for, heparin induced thrombocytopenia (HIT) and are undergoing percutaneous co
ARIPIPRAZOLE
CAS:129722-12-9
Formula: C23H27Cl2N3O2
T1566
99%
Aripiprazole is an atypical antipsychotic medication used for the treatment of schizophrenia. It has also recently received FDA approval for the treatment of acute manic and mixed episodes associated with bipolar disorder. Aripiprazole appears to mediate
ARISTOLOCHIC ACID
CAS:313-67-7
Formula: C17H11NO7
T2801
98%
Aristolochic acids are a family of carcinogenic, mutagenic, and nephrotoxic compounds commonly found in the Birthwort (Aristolochiaceae) family of plants.
ARMODAFINIL
CAS:112111-43-0
Formula: C15H15NO2S
T0417
90%
Modafinil is a stimulant drug marketed as a wakefulness promoting agent and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexin
ARN-509
CAS:956104-40-8
Formula: C21H15F4N5O2S
T2339
98%
ARN-509 is a selective and competitive androgen receptor inhibitor with IC50 of 16 nM in a cell-free assay, useful for prostate cancer treatment. Phase 3.
ARQ 621
CAS:1095253-39-6
Formula: C28H24Cl2FN5O2
T6393
98%
ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.
ARRY-380
CAS:937265-83-3
Formula: C29H27N7O4S
T2518
99%+
HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family. Amplification or overexpression of this oncogene has been shown to play an important role in the development and progression of certain aggressive types of breast cance
ARTEMETHER
CAS:71963-77-4
Formula: C16H26O5
T1323
98%
Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and ma
ARTEMISININ
CAS:63968-64-9
Formula: C15H22O5
T0392
97%
Artemisinin is a drug used to treat multi-drug resistant strains of falciparum malaria (as well as increasingly vivax malaria). The compound is isolated from the plant Artemisia annua, a herb described in Chinese traditional medicine, though it is usually
ARTESUNATE
CAS:88495-63-0
Formula: C19H28O8
T0433
98%
Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 M for small cell lung carcinoma cell line H69. Artesunate is a semi-synthetic derivative of artemisinin that is water-soluble and may therefore be given by injection. Artesunate
AS 602801
CAS:848344-36-5
Formula: C25H23N5O2S
T2675
100%
AS 602801(Bentamapimod) is a novel, orally active inhibitor of JNK.
AS-252424
CAS:900515-16-4
Formula: C14H8FNO4S
T6208
98%
AS-252424 is a novel, potent PI3K? inhibitor with IC50 of 30 nM with 30-fold selectivity for PI3K? than PI3Ka, and low inhibitory activity towards PI3Kd/.
AS-604850
CAS:648449-76-7
Formula: C11H5F2NO4S
T6394
98%
AS-604850 is a selective, ATP-competitive PI3K? inhibitor with IC50 of 250 nM, over 80-fold selectivity for PI3K? than PI3Kd/, and 18-fold more selective for PI3K? than PI3Ka.
AS-605240
CAS:648450-29-7
Formula: C12H7N3O2S
T2248
98%
AS-605240 is a potent and selective inhibitor of PI 3-kinase ? (PI3K?) (IC50 = 8 nM). AS-605240 displays 30-fold selectivity over PI3Kd and PI3K and 7.5-fold selectivity over PI3Ka.
AS601245
CAS:345987-15-7
Formula: C20H16N6S
T2343
98%
AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK) (hJNK1: IC50=150nM, hJNK2: IC50=220nM and hJNK3: IC50=70 nM), has neuroprotective properties.
ASARYLALDEHYDE
CAS:4460-86-0
Formula: C10H12O4
T2826
98%
Asaraldehyde is a natural COX-2 inhibitor, exhibiting 17-fold selectivity over COX-1.
ASCOMYCIN
CAS:104987-12-4
Formula: C43H69NO12
T2481
100%
Ascomycin (FK520), an FK-506 analog, is a neutral macrolide immunosuppressant, which prevents rejection after an organ transplant. Phase 3.
ASCORBYL PALMITATE
CAS:137-66-6
Formula: C22H38O7
T0752
98%
Ascorbyl palmitate is an ester formed from ascorbic acid and palmitic acid creating a fat-soluble form of vitamin C.
ASENAPINE MALEATE
CAS:85650-56-2
Formula: C21H20ClNO5
T1951
99%+
Developed by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine also belongs to the diben
ASIATIC ACID
CAS:464-92-6
Formula: C30H48O5
T2827
95%
ActionsAsiatic acid is commonly used in wound healing. Asiatic acid has antioxidant,anti-inflammatory and neuroprotective properties.Packaging500 mg in glass bottleApplicationStarting material for asiatic acid derivative synthesis for use as: Anticance
ASIATICOSIDE
CAS:16830-15-2
Formula: C48H78O19
T3025
99%+
Asiaticoside (Madecassol) is the active chemical component of the plant Centella asiatica. Asiaticoside is used to study potential treatments for wounds and burns.
ASP3026
CAS:1097917-15-1
Formula: C29H40N8O3S
T1962
98%
ASP3026 is a novel and selective inhibitor for ALK with IC50 of 3.5 nM. Phase 1.
ASPARTAME
CAS:22839-47-0
Formula: C14H18N2O5
T0697
98%
Flavoring agent sweeter than sugar, metabolized as PHENYLALANINE and ASPARTIC ACID.
ASPEROSAPONIN ?
CAS:39524-08-8
Formula: C47H76O18
T2698
98%
Extracted from Dipsacus asperoides C. Y. Cheng et T .M. Ai.;Suitability:1g dissolved in 87ml water,3ml boiling water;Store the product in sealed,cool and dry condition
ASPIRIN
CAS:50-78-2
Formula: C9H8O4
T0005
100%
Aspirin (Acetylsalicylic acid) is a potent and selective inhibitor of cyclooxygenase (COX) with a broad range of pharmacological activities including anti-inflammation and pain relief. Multiple studies have accumulated sufficient evidence to establish the
AST-1306
CAS:1050500-29-2
Formula: C31H26ClFN4O5S
T6331
98%
AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, also effective in mutation EGFR T790M/L858R, more potent to ErbB2-overexpressing cells, 3000-fold selective for ErbB family than other kinases,
ASTAXANTHIN
CAS:472-61-7
Formula: C40H52O4
T3138
90%
astaxanthin is a natural dietary component. Natural astaxanthin is generally recognized as safe (GRAS) by the FDA
ASTEMIZOLE
CAS:68844-77-9
Formula: C28H31FN4O
T1278
98%
Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
ASTILBIN
CAS:29838-67-3
Formula: C21H22O11
T2794
98%
Actions Flavonoid phytochemical found in St. John's wort and Traditional Chinese Medicine herbal preparations. Immunosuppresive. Antiproliferative. Application Astilbin from Engelhardtia roxburghiana,a flavonoid phytochemical with antibacterial activity
ASTRAGALOSIDE A
CAS:83207-58-3
Formula: C41H68O14
T6395
98%
Astragaloside A (Astragaloside IV) is the primary pure saponin isolated from Astragalus membranaceus, which has been widely used for the treatment of cardiovascular diseases.
ASTRAGALOSIDE IV
CAS:84687-43-4
Formula: C41H68O14
T2973
98%
Astragaloside IV is generally considered to be the primary active ingredient in Astragalus extract,an herbal extract which has been famous for literally thousands of years for its anti-aging properties.
AT-56
CAS:162640-98-4
Formula: C25H27N5
T1866
98%
AT56, a specific inhibitor of prostaglandin D2 synthase enzymatic activity, blunted adipogenic aldosterone effects.
AT101
CAS:90141-22-3
Formula: C30H30O8
T6314
98%
AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 M, 0.48 M and 0.18 M.
AT101 ACETATE
CAS:866541-93-7
Formula: C30H30O8C2H4O2
T6396
98%
AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 M, 0.48 M and 0.18 M; does not inhibit BIR3 domain and BID. Phase 2.
AT13148
CAS:1056901-62-2
Formula: C17H16ClN3O
T2482
98%
AT13148 is an oral, ATP-competitive, multi-AGC kinase inhibitor with IC50 of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively. Phase 1.
AT13387
CAS:912999-49-6
Formula: C24H31N3O3
T6284
98%
Onalespib (AT13387) is a selective potent Hsp90 inhibitor with IC50 of 18 nM in A375 cells, displays a long duration of anti-tumor activity. Phase 2.
AT7519
CAS:844442-38-2
Formula: C16H17Cl2N5O2
T6205
98%
AT7519 is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM. It is less potent to CDK3 and little active to CDK7. Phase 2.
AT7519 HYDROCHLORIDE
CAS:902135-91-5
Formula: C16H18Cl3N5O2
T1778
98%
AT7519 is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM. It is less potent to CDK3 and little active to CDK7. Phase 2.
AT7867
CAS:857531-00-1
Formula: C20H20ClN3
T6304
98%
AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family.
AT9283
CAS:896466-04-9
Formula: C19H23N7O2
T3068
98%
AT9283 is a potent JAK2/3 inhibitor with IC50 of 1.2 nM/1.1 nM in cell-free assays; also potent to Aurora A/B, Abl(T315I). Phase 2.
ATAZANAVIR
CAS:198904-31-3
Formula: C38H52N6O7
T0100L
99%
Atazanavir (formerly known as BMS-232632) is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV). Atazanavir is distinguished from other PIs in that i
ATAZANAVIR SULFATE
CAS:229975-97-7
Formula: C38H52N6O7H2SO4
T0100
99%
Atazanavir (formerly known as BMS-232632) is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV). Atazanavir is distinguished from other PIs in tha
ATB-346
CAS:1226895-20-0
Formula: C21H19NO3S
T1867
98%
ATB-346 is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.
ATENOLOL
CAS:29122-68-7
Formula: C14H22N2O3
T0007
98%
A cardioselective beta-1 adrenergic blocker possessing properties and potency similar to PROPRANOLOL, but without a negative inotropic effect.
ATGLISTATIN
CAS:1469924-27-3
Formula: C17H21N3O
T1875
98%
Atglistatin is a highly potent, and selective inhibitor of adipose triglyceride lipase (ATGL) with IC50 of 0.7 M, high selectivity over other key metabolic lipases.
ATOMOXETINE HYDROCHLORIDE
CAS:82248-59-7
Formula: C17H22ClNO
T0869
97%
Atomoxetine is the first non-stimulant drug approved for the treatment of attention-deficit hyperactivity disorder (ADHD). It is sold in the form of the hydrochloride salt of atomoxetine. This chemical is manufactured and marketed under the brand name Str
ATOPAXAR
CAS:751475-53-3
Formula: C29H38FN3O5
T1986
98%
Atopaxar is a reversible protease activated receptor (PAR)-1 thrombin receptor antagonist that interferes with platelet signaling. The effects of PAR-1 antagonists on biomarkers remain unknown. The primary objective was to assess the effects of atopaxar o
ATOPAXAR HYDROBROMIDE
CAS:474550-69-1
Formula: C29H39BrFN3O5
T1986L
98%
Atopaxar is a reversible protease activated receptor (PAR)-1 thrombin receptor antagonist that interferes with platelet signaling. The effects of PAR-1 antagonists on biomarkers remain unknown. The primary objective was to assess the effects of atopaxar o
ATORVASTATIN HEMICALCIUM SALT
CAS:134523-03-8
Formula: 2(C33H34FN2O5)Ca
T3116
99%
Atorvastatin Calcium is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol.
ATOVAQUONE
CAS:95233-18-4
Formula: C22H19ClO3
T1491
98%
A hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.
ATP DISODIUM SALT
CAS:987-65-5
Formula: C10H14N5O13P32Na
T1352
95%
ATP is a disodium salt form of adenosine-triphosphate which is a multifunctional nucleoside triphosphate.
ATRACURIUM BESYLATE
CAS:64228-81-5
Formula: C53H72N2O122(C6H5O3S)
T6397
98%
Atracurium Besylate is a neuromuscular blocking agent with ED95 of 0.2 mg/kg.
ATROPIC ACID
CAS:492-38-6
Formula: C9H8O2
T0629
98%+
Used as a medicine, organic synthesis intermediates
ATROPINE
CAS:51-55-8
Formula: C17H23NO3
T0375
99%
Atropine is an antimuscarinic agent and has shown the pharmacological effects because of binding to muscarinic acetylcholine receptors. Atropine, the orthosteric antagonist, has been reported to compete with [3H]-NMS for all muscarinic subtypes with a pot
ATROPINE SULFATE
CAS:55-48-1
Formula: 2C17H23NO3H2SO4
T0375L2
95%
Atropine is an antimuscarinic agent and has shown the pharmacological effects because of binding to muscarinic acetylcholine receptors. Atropine, the orthosteric antagonist, has been reported to compete with [3H]-NMS for all muscarinic subtypes with a pot
ATROPINE SULFATE MONOHYDRATE
CAS:5908-99-6
Formula: C34H46N2O6H2SO4H2O
T0375L
97%
Atropine is an antimuscarinic agent and has shown the pharmacological effects because of binding to muscarinic acetylcholine receptors. Atropine, the orthosteric antagonist, has been reported to compete with [3H]-NMS for all muscarinic subtypes with a
AURANOFIN
CAS:34031-32-8
Formula: C20H34AuO9PS
T1303
98%
An oral chrysotherapeutic agent for the treatment of rheumatoid arthritis. Its exact mechanism of action is unknown, but it is believed to act via immunological mechanisms and alteration of lysosomal enzyme activity. Its efficacy is slightly less than tha
AVAGACESTAT (BMS-708163)
CAS:1146699-66-2
Formula: C20H17ClF4N4O4S
T6249
98%
Avagacestat (BMS-708163) is a potent, selective, orally bioavailable ?-secretase inhibitor of A40 and A42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.
AVANAFIL
CAS:330784-47-9
Formula: C23H26ClN7O3
T2334
98%
Avanafil is a highly selective PDE5 inhibitor with IC50 of 5.2 nM, >121-fold selectivity over other PDEs.
AVASIMIBE
CAS:166518-60-1
Formula: C29H43NO4S
T2753
99%
Avasimibe inhibits ACAT with IC50 of 3.3 M, also inhibits human P450 isoenzymes CYP2C9, CYP1A2 and CYP2C19 with IC50 of 2.9 M, 13.9 M and 26.5 M, respectively.
AVERMECTIN B1
CAS:71751-41-2
Formula: C48H72O14
T0956
98%
Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic.
AVL-292
CAS:1202757-89-8
Formula: C22H22FN5O3
T2603
100%
CC-292 (AVL-292) is a covalent, orally active, and highly selective BTK inhibitor with IC50 of <0.5 nM, displaying at least 1400-fold selectivity over the other kinases assayed. Phase 1.
AVN-944
CAS:297730-17-7
Formula: C25H27N5O5
T1979
98%
AVN-944(VX-944) is a selective, noncompetitive inhibitor of the enzyme directed against human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
AVOBENZONE
CAS:70356-09-1
Formula: C20H22O3
T0695
98%
Avobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative.
AWD 131-138
CAS:188116-07-6
Formula: C13H14ClN3O2
T1860
98%
AWD 131-138(Imepitoin) is a new low-affinity partial benzodiazepine receptor agonist with potent anticonvulsant and anxiolytic properties in rodent models.
AXITINIB
CAS:319460-85-0
Formula: C22H18N4OS
T1452
99%
Axitinib is an oral, potent, and selective inhibitor of vascular endothelial growth factor receptors (VEGFR) 1, 2, and 3. Axitinib is marketed under the name Inlyta?, and if one previous systemic therapy for kidney cell cancer has failed, axitinib is indi
AYRTOL
CAS:88-04-0
Formula: C8H9ClO
T0898
99%
Chloroxylenol (4-chloro-3,5-dimethylphenol) is a broad spectrum antimicrobial chemical compound used to control bacteria, algae, fungi and virus. It is used in hospitals and households for disinfection and sanitation.
AZ 628
CAS:878739-06-1
Formula: C27H25N5O2
T6318
98%
AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.
AZ 960
CAS:905586-69-8
Formula: C18H16F2N6
T6309
98%
AZ 960 is a novel ATP competitive JAK2 inhibitor with IC50 and Ki of <3 nM and 0.45 nM, 3-fold selectivity of AZ960 for JAK2 over JAK3.
AZ-33
CAS:1370290-34-8
Formula: C25H27N3O6S
T3175
98%
AZ-33 is an LDHA Inhibitor.
AZ191
CAS:1594092-37-1
Formula: C24H27N7O
T6257
98%
AZ191 is a potent and selective DYRK1B inhibitor with IC50 of 17 nM, about 5- and 110-fold selectivity over DYRK1A and DYRK2, respectively.
AZ20
CAS:1233339-22-4
Formula: C21H24N4O3S
T1958
98%
AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM in a cell-free assay, 8-fold selectivity over mTOR.
AZ3146
CAS:1124329-14-1
Formula: C24H32N6O3
T2689
100%
AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM, contributes to recruitment of CENP-E (kinesin-related motor protein), less potent to FAK, JNK1, JNK2, and Kit.
AZ5104
CAS:1421373-98-9
Formula: C27H31N7O2
T2491
99%+
AZ5104, the demethylated metabolite of AZD-9291, is a potent EGFR inhibitor with IC50 of <1 nM, 6 nM, 1 nM, and 25 nM for EGFR (L858R/T790M), EGFR (L858R), EGFR (L861Q), and EGFR (wildtype), respectively. Phase 1.
AZACYCLONOL
CAS:115-46-8
Formula: C18H21NO
T0318
98%
Azacyclonol, also known as ?-pipradol, is a drug used to diminish hallucinations in psychotic individuals.
AZASETRON HYDROCHLORIDE
CAS:123040-16-4
Formula: C17H20ClN3O3HCl
T1528
98%
Azasetron Hydrochloride is a 5-HT3 receptor antagonist which is used as an anti-emetic.Azasetron inhibited the specific binding of [3H]quipazine to 5-HT3 receptors at the synaptic membranes of the rat cerebral cortex.
AZATADINE DIMALEATE
CAS:3978-86-7
Formula: C28H30N2O8
T0236
98%
Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and
AZATHIOPRINE
CAS:446-86-6
Formula: C9H7N7O2S
T1237
99%
Azathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases.
AZD-1480
CAS:935666-88-9
Formula: C14H14ClFN8
T3069
98%
AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM in a cell-free assay, selectivity against JAK3 and Tyk2, and to a smaller extent against JAK1. Phase 1.
AZD-2461
CAS:1174043-16-3
Formula: C22H22FN3O3
T2484
98%
AZD2461 is a novel PARP inhibitor with low affinity for Pgp than Olaparib. Phase 1.
AZD-3463
CAS:1356962-20-3
Formula: C24H25ClN6O
T1967
98%
AZD3463 is a novel orally bioavailable ALK inhibitor with Ki of 0.75 nM, which also inhibits IGF1R with equivalent potency.
AZD-3965
CAS:1448671-31-5
Formula: C21H24F3N5O5S
T3210
98%
AZD-5438
CAS:602306-29-6
Formula: C18H21N5O2S
T2506
99%
AZD5438 is a potent inhibitor of CDK1/2/9 with IC50 of 16 nM/6 nM/20 nM in cell-free assays. It is less potent to CDK5/6 and also inhibits GSK3. Phase 1.
AZD-8055
CAS:1009298-09-2
Formula: C25H31N5O4
T1859
98%
AZD8055 is a novel ATP-competitive mTOR inhibitor with IC50 of 0.8 nM in MDA-MB-468 cells with excellent selectivity (?1,000-fold) against PI3K isoforms and ATM/DNA-PK. Phase 1.
AZD-9291
CAS:1421373-65-0
Formula: C28H33N7O2
T2490
98%
AZD9291 is an oral, irreversible, and mutant-selective EGFR inhibitor with IC50 of 12.92, 11.44 and 493.8 nM for Exon 19 deletion EGFR, L858R/T790M EGFR, and WT EGFR in LoVo cells, respectively. Phase 3.
AZD1080
CAS:612487-72-6
Formula: C19H18N4O2
T1741
98%
AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor, inhibits human GSK3a and GSK3 with Ki of 6.9 nM and 31 nM, respectively, shows >14-fold selectivity against CDK2, CDK5, CDK1 and Erk2.
AZD1152-HQPA
CAS:722544-51-6
Formula: C26H30FN7O3
T2602
99%
Barasertib (AZD1152-HQPA) is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay, ~3700 fold more selective for Aurora B over Aurora A. Phase 1.
AZD1208
CAS:1204144-28-4
Formula: C21H21N3O2S
T2300
98%
AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases and is currently undergoing Phase I testing and dose escalation studies in AML. AZD1208 suppresses the growth of MOL
AZD1981
CAS:802904-66-1
Formula: C19H17ClN2O3S
T6399
98%
AZD1981 is a potent, selective CRTh2 (DP2) receptor antagonist with IC50 of 4 nM, showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1. Phase 2.
AZD2014
CAS:1009298-59-2
Formula: C25H30N6O3
T1961
98%
AZD2014 is a novel mTOR inhibitor with IC50 of 2.8 nM in a cell-free assay; highly selective against multiple PI3K isoforms (a//?/d). Phase 2.
AZD2858
CAS:486424-20-8
Formula: C21H23N7O3S
T1957
98%
AZD2858 is a selective GSK-3 inhibitor with an IC50 of 68 nM, inhibits tau phosphorylation at the S396 site, activates Wnt signaling pathway.
AZD2932
CAS:883986-34-3
Formula: C24H25N5O4
T1836
98%
AZD2932 is a new series of quinazoline ether inhibitor which potently inhibits VEGFR-2 and PDGFR with IC50s of 4 nM/8 nM/ 7 nM for PDGFR/VEGFR-2/Flt-3.
AZD3514
CAS:1240299-33-5
Formula: C25H32F3N7O2
T6400
98%
AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 M and has ability of reducing AR protein expression.Phase 1.
AZD4547
CAS:1035270-39-3
Formula: C26H33N5O3
T1948
98%
AZD4547 is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM in cell-free assays, weaker activity against FGFR4, VEGFR2(KDR), and little activity observed against IGFR, CDK2, and p38. Phase 2/3.
AZD5363
CAS:1143532-39-1
Formula: C21H25ClN6O2
T1920
98%
PI4K/Akt/mTOR Signaling Akt inhibitor
AZD6482
CAS:1173900-33-8
Formula: C22H24N4O4
T6087
98%
AZD6482 is a PI3K inhibitor with IC50 of 10 nM, 8-, 87- and 109-fold more selective to PI3K than PI3Kd, PI3Ka and PI3K?. Phase 1.
AZD7545
CAS:252017-04-2
Formula: C19H18ClF3N2O5S
T2447
98%
AZD7545 is a potent PDHK inhibitor with IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2, respectively.
AZD7762
CAS:860352-01-8
Formula: C17H19FN4O2S
T6093
98%
AZD7762 is a potent and selective inhibitor of Chk1 with IC50 of 5 nM. It is equally potent against Chk2 and less potent against CAM, Yes, Fyn, Lyn, Hck and Lck. Phase 1.
AZD8330
CAS:869357-68-6
Formula: C16H17FIN3O4
T6083
98%
AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with IC50 of 7 nM. Phase 1.
AZD8931 (SAPITINIB)
CAS:848942-61-0
Formula: C23H25ClFN5O3
T6092
98%
AZD8931 is a reversible, ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 with IC50 of 4 nM, 3 nM and 4 nM, more potent than Gefitinib or Lapatinib against NSCLC cell, 100-fold more selective for the ErbB family than MNK1 and Flt. Phase 2.
AZELAIC ACID
CAS:123-99-9
Formula: C9H16O4
T0926
97%
Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is a natural substance that is produced by Malassezia furfur (also known as Pityrosporum ovale), a yeast that lives on normal skin. It is effective against a numbe
AZELASTINE
CAS:58581-89-8
Formula: C22H25Cl2N3O
T0211
98%
Azelastine hydrochloride is a potent, second-generation, selective, histamine antagonist.
AZELASTINE HYDROCHLORIDE
CAS:79307-93-0
Formula: C22H24ClN3OHCl
T0211L
98%
Azelastine hydrochloride is a potent, second-generation, selective, histamine antagonist.
AZELIRAGON
CAS:603148-36-3
Formula: C32H38ClN3O2
T2507
98%
TTP488 is an antagonist at the Receptor for Advanced Glycation End products, is evaluated as a potential treatment for patients with mild-to-moderate Alzheimer_acute_s disease (AD).
AZELNIDIPINE
CAS:123524-52-7
Formula: C33H34N4O6
T0121
99%
Azelnidipine is a dihydropyridine calcium channel blocker.
AZILSARTAN
CAS:147403-03-0
Formula: C25H20N4O5
T1057
98%
Azilsartan medoxomil is an angiotensin II receptor antagonist indicated for the treatment of mild to moderate essential hypertension. Azilsartan medoxomil is a prodrug of Azilsartan marketed as Edarbi by Takeda. Azilsartan medoxomil has so far been shown
AZILSARTAN MEDOXOMIL
CAS:863031-21-4
Formula: C30H24N4O8
T6219
98%
Azilsartan Medoxomil is a potent angiotensin II type 1 (AT1) receptor antagonist, inhibits the RAAS, with an IC50 of 2.6 nM, exhibits >10,000-fold selectivity over AT2.
AZILSARTAN MEDOXOMIL MONOPOTASSIUM
CAS:863031-24-7
Formula: C30H23N4O8K
T0481
98%
Azilsartan medoxomil(TAK 491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.
AZITHROMYCIN
CAS:76801-85-9
Formula: C37H70N2O12
T3265
98%
Azithromycin, derived from erythromycin, is a antibiotic. Azithromycin binds to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA.
AZITHROMYCIN HYDRATE
CAS:117772-70-0
Formula: C38H72N2O122H2O
T1419
98%
Azithromycin Dihydrate is an acid stable orally administered macrolide antimicrobial drug, structurally related to erythromycin
AZLOCILLIN SODIUM SALT
CAS:37091-65-9
Formula: C20H22N5NaO6S
T0049
98%
Azlocillin is an acylampicillin with a broad spectrum against bacteria
AZOBENZENE
CAS:103-33-3
Formula: C12H10N2
T0609
98%+
Azobenzene is a chemical compound composed of two phenyl rings linked by a N=N double bond. It is the simplest example of an aryl azo compound. The term 'azobenzene' or simply 'azo' is often used to refer to a wide class of molecules that share the core a
AZTREONAM
CAS:78110-38-0
Formula: C13H17N5O8S2
T1029
95%
A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-p
B-AP15
CAS:1009817-63-3
Formula: C22H17N3O6
T1932
98%
b-AP15(NSC687852) is a specific inhibitor of the deubiquitinating enzymes UCHL5 and Usp14 of the 26S proteasome. It blocks the deubiquitinating activity of the 26S proteasome.
B-RAF IN 1
CAS:950736-05-7
Formula: C29H24F3N5O
T1845
98%
B-Raf IN 1 is a highlt potent and selective B-Raf inhibitor with IC50 of 24 nM; equipotent against c-Raf (IC50= 25 nM).
B-RAF INHIBITOR 1
CAS:1093100-40-3
Formula: C26H19ClN8
T2074
98%
B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively.
BACCATIN III
CAS:27548-93-2
Formula: C31H38O11
T2788
98%
Baccatin III is an isolate of the Pacific yew tree (Taxus brevifolia) and related species. Baccatin III is a precursor to the anti-cancer drug paclitaxel (Taxol).
BACITRACIN
CAS:1405-87-4
Formula: C66H103N17O16S
T1226
65IU/mg
Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, which disrupts both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synthesis.
BACITRACIN ZINC
CAS:1405-89-6
Formula: C66H101N17O16SZn
T2208
98%
Bacitracin Zinc is a dephosphorylation of the C55-isoprenyl pyrophosphate interference for inhibition of cleavage of Tyr from Met-enkephalin with IC50 of 10 M.
BACLOFEN
CAS:1134-47-0
Formula: C10H12ClNO2
T1065
99%
A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites
BAF312 (SIPONIMOD)
CAS:1230487-00-9
Formula: C29H35F3N2O3
T6403
98%
BAF312 (Siponimod) is a next-generation S1P receptor modulator, selective for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, exhibits >1000-fold selectivity over S1P2, S1P3 and S1P4 receptors. Phase 3.
BAFETINIB
CAS:859212-16-1
Formula: C30H31F3N8O
T6311
98%
Bafetinib (INNO-406) is a potent and selective dual Bcr-Abl/Lyn inhibitor with IC50 of 5.8 nM/19 nM, does not inhibit the phosphorylation of the T315I mutant and is less potent to PDGFR and c-Kit. Phase 2.
BAFILOMYCIN A1
CAS:88899-55-2
Formula: C35H58O9
T6740
98%
Bafilomycin A1 is a vacuolar?H+-ATPase?inhibitor with?IC50of 0.45 nM.
BAICALEIN
CAS:491-67-8
Formula: C15H10O5
T2858
98%
The flavonoid component of Nepalese and Sino-Japanese crude drugs.1,2 Baicalein,a major flavone of Scutellariae baicalensis,inhibits the 12-lipoxygenase (12-LOX) pathway of arachidonic acid metabolism,which inhibits cancer cell proliferation and induce
BAICALIN
CAS:21967-41-9
Formula: C21H18O11
T2775
98%
Extracted from Labiatae Scutellaria baicalensis Georgi;Suitability:N,N- two DMF,pyridine;Store the product in sealed,cool and dry condition
BALICATIB
CAS:354813-19-7
Formula: C23H33N5O2
T1850
98%
Balicatib is an inhibitor of cathepsin K with IC50 value of 1.4nM [1].Balicatib is highly selective against cathepsin K over cathepsin B, L and S in the in vitro enzyme assay. However, the selectivity is not so high in cell-based enzyme assay. The lysosom
BALOFLOXACIN
CAS:127294-70-6
Formula: C20H24FN3O4
T0116
99%
Balofloxacin is a quinolone antibiotic, inhibiting the synthesis of bacterial DNA by interference with the enqyme DNA gyrase.
BAM7
CAS:331244-89-4
Formula: C21H19N5O2S
T2453
98%
BAM 7 is a direct and selective activator of proapoptotic Bax with EC50 of 3.3 M.
BAMBUTEROL HYDROCHLORIDE
CAS:81732-46-9
Formula: C18H30ClN3O5
T1446
98%
Bambuterol is a long acting beta-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline.
BANISTERINE MONOHYDRATE
CAS:442-51-3
Formula: C13H12N2O
T1711
98%
Alkaloid isolated from seeds of Peganum harmala L., Zygophyllaceae. It is identical to banisterine, or telepathine, from Banisteria caapi and is one of the active ingredients of hallucinogenic drinks made in the western Amazon region from related plants.
BAPTA-AM
CAS:126150-97-8
Formula: C34H40N2O18
T6245
98%
BAPTA-AM is a selective, membrane-permeable calcium chelator.
BARDOXOLONE METHYL
CAS:218600-53-4
Formula: C32H43NO4
T6165
98%
Bardoxolone Methyl is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities. Phase 3.
BARICITINIB
CAS:1187594-09-7
Formula: C16H17N7O2S
T2485
100%
Baricitinib (LY3009104, INCB028050) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM in cell-free assays, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Phase 3.
BARICITINIB PHOSPHATE
CAS:1187595-84-1
Formula: C16H20N7O6PS
T2360
98%
Baricitinib (LY3009104, INCB028050) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM in cell-free assays, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Phase 3.
BASIBROL
CAS:75-80-9
Formula: C2H3Br3O
T0807
97%
2,2,2-Tribromoethanol is white crystal or powder, sensitive to light and air.
BATIMASTAT (BB-94)
CAS:130370-60-4
Formula: C23H31N3O4S2
T6011
98%
Batimastat (BB-94) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-1, MMP-2, MMP-9, MMP-7 and MMP-3 with IC50 of 3 nM, 4 nM, 4 nM, 6 nM and 20 nM, respectively. Also inhibits the activitity of other metalloproteases, such as ADA
BATYL ALCOHOL
CAS:544-62-7
Formula: C21H44O3
T3004
98%
n/a
BAVACHININ
CAS:19879-30-2
Formula: C21H22O4
T3056
98%
Bavachinin(7-O-Methylbavachin) is a natural compound isolated from the Chinese herb Fructus Psoraleae;has potent anti-angiogenic activity.
BAY 11-7082
CAS:19542-67-7
Formula: C10H9NO2S
T1902
98%
BAY 11-7082 is a NF-?B inhibitor, inhibits TNFa-induced I?Ba phosphorylation with IC50 of 10 M in tumor cells. Also inhibiting components of the ubiquitin system.
BAY 11-7085
CAS:196309-76-9
Formula: C13H15NO2S
T1934
98%
BAY 11-7085 is an irreversible inhibitor of TNFa-induced I?Ba phosphorylation with IC50 of 10 M.
BAY 57-1293
CAS:348086-71-5
Formula: C18H18N4O3S2
T2504
98%
Pritelivir (BAY 57-1293) is a potent helicase primase inhibitor, exhibiting antiviral effect on herpes simplex virus (HSV) with IC50 of 20 nM for both HSV-1 and HSV-2.
BAY 80-6946
CAS:1032568-63-0
Formula: C23H28N8O4
T6322
98%
BAY 80-6946 (Copanlisib) is a potent and highly selective reversible PI3K inhibitor for PI3Ka/ with IC50 of 0.469 nM/3.72 nM. Phase 2.
BAY 87-2243
CAS:1227158-85-1
Formula: C26H26F3N7O2
T2488
98%
BAY 87-2243 is a potent and selective hypoxia-inducible factor-1 (HIF-1) inhibitor. Phase 1.
BAZEDOXIFENE ACETATE
CAS:198481-33-3
Formula: C30H34N2O3HCl
T2544
99%
azedoxifene hydrochloride is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERa and ER with IC50 of 23 nM and 89 nM, respectively.
BAZEDOXIFENE HCL
CAS:198480-56-7
Formula: C30H34N2O3HCl
T6404
98%
Bazedoxifene HCl is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERa and ER with IC50 of 23 nM and 89 nM, respectively.
BD-1047 DIHYDROBROMIDE
CAS:138356-21-5
Formula: C13H22Br2Cl2N2
T1740
98%
BD-1047 dihydrobromide is a selective functional antagonist of sigma receptors, shows antipsychotic activity in animal models predictive of efficacy in schizophrenia.
BECLAMIDE
CAS:501-68-8
Formula: C10H12ClNO
T1249
98%
Beclamide is used as antiepiletics.
BECLOMETASONE DIPROPIONATE
CAS:5534-09-8
Formula: C28H37ClO7
T1127
An anti-inflammatory, synthetic glucocorticoid. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of ASTHMA.
BEDAQUILINE
CAS:843663-66-1
Formula: C32H31BrN2O2
T2585
98%
Bedaquiline(TMC207; R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis.
BELINOSTAT
CAS:414864-00-9
Formula: C15H14N2O4S
T1852
98%
Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibit
BELNACASAN (VX-765)
CAS:273404-37-8
Formula: C24H33ClN4O6
T6090
98%
Belnacasan (VX-765) is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM. Phase 2.
BENACTYZINE HYDROCHLORIDE
CAS:57-37-4
Formula: C20H26ClNO3
T2571
98%
Benactyzine hydrochloride is a centrally acting muscarinic antagonist. Benactyzine has been used in the treatment of depression and is used in research to investigate the role of cholinergic systems on behavior.
BENAZEPRIL HYDROCHLORIDE
CAS:86541-74-4
Formula: C24H29ClN2O5
T0180
99%
Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprila
BENDAMUSTINE HYDROCHLORIDE
CAS:3543-75-7
Formula: C16H21Cl2N3O2HCl
T0095
99%
Bendamustine hydrochloride is an alkylating agent associated with DNA damage with IC50 of 50 M
BENDAZAC L-LYSINE
CAS:81919-14-4
Formula: C22H28N4O5
T3141
99%
n/a
BENDAZOL
CAS:621-72-7
Formula: C14H12N2
T1322
96%
n/a
BENDROFLUMETHIAZIDE
CAS:73-48-3
Formula: C15H14F3N3O4S2
T1204
98%
A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
BENFLUOREX HYDROCHLORIDE
CAS:23642-66-2
Formula: C19H21ClF3NO2
T0919
98%
Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine. It was patented and manufactured by a French pharmaceutical company Servier. On 18 December 2009, the European Medicines Agency (EMEA) recommended the withdra
BENFOTIAMINE
CAS:22457-89-2
Formula: C19H23N4O6PS
T1129
98%
Benfotiamine, the lipid-soluble thiamine derivative used as a treatment for diabetic neuropathy, can inhibit three major pathways(the hexosamine pathway, the advanced glycation end product (AGE) formation pathway and the diacylglycerol (DAG)?protein kinas
BENGENIN
CAS:477-90-7
Formula: C14H16O9
T0122
100%
Bergenin monohydrate is an isocoumarin isolated from various medicinal plants. Shows mild anti-HIV activity,antihepatotoxic activity and antiulcer activity.
BENIDIPINE HCL
CAS:91599-74-5
Formula: C28H31N3O6HCl
T6227
98%
Benidipine HCl is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker.
BENSERAZIDE HYDROCHLORIDE
CAS:14919-77-8
Formula: C10H15N3O5HCl
T1517
98%
An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reac
BENZALKONIUM CHLORIDE
CAS:8001-54-5
Formula: C17H30ClN
T0336
98%
Benzalkonium chloride is a cationic surface-acting agent belonging to the quaternary ammonium group. It has three main categories of use: as a biocide, a cationic surfactant, and phase transfer agent in the chemical industry. The chemical is a heterogeneo
BENZBROMARONE
CAS:3562-84-3
Formula: C17H12Br2O3
T1274
99%
Uricosuric that acts by increasing uric acid clearance. It is used in the treatment of gout.
BENZETHONIUM CHLORIDE
CAS:121-54-0
Formula: C27H42ClNO2
T0401
97%
Bactericidal cationic quaternary ammonium surfactant used as a topical anti-infective agent. It is an ingredient in medicaments, deodorants, mouthwashes, etc., and is used to disinfect apparatus, etc., in the food processing and pharmaceutical industries,
BENZOCAINE
CAS:94-09-7
Formula: C9H11NO2
T0924
A surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.
BENZOIC ACID
CAS:65-85-0
Formula: C7H6O2
T0833
99%
Benzoic acid is a Nitrogen Binding Agent. The mechanism of action of benzoic acid is as an Ammonium Ion Binding Activity.
BENZOYL PEROXIDE
CAS:94-36-0
Formula: C14H10O4
T0764
98%
A peroxide derivative that has been used topically for BURNS and as a dermatologic agent in the treatment of ACNE and POISON IVY DERMATITIS. It is used also as a bleach in the food industry.
BENZTHIAZIDE
CAS:91-33-8
Formula: C15H14ClN3O4S3
T0782
98%
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potas
BENZTROPINE MESYLATE
CAS:132-17-2
Formula: C21H25NOCH4SO3
T1336
95%
Benzatropine is an anticholinergic drug used in patients to reduce the side effects of antipsychotic treatment. Benzatropine is also a second-line drug for the treatment of Parkinson's disease. It improves tremor, but not rigidity and bradykinesia.
BENZYDAMINE HYDROCHLORIDE
CAS:132-69-4
Formula: C19H23N3OHCl
T0726
97%
A benzyl-indazole having analgesic, antipyretic, and anti-inflammatory effects. It is used to reduce post-surgical and post-traumatic pain and edema and to promote healing. It is also used topically in treatment of RHEUMATIC DISEASES and INFLAMMATION of t
BENZYL ALCOHOL
CAS:100-51-6
Formula: C7H8O
T0732
99%
A colorless liquid with a sharp burning taste and slight odor. It is used as a local anesthetic and to reduce pain associated with LIDOCAINE injection. Also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery
BENZYL BENZOATE
CAS:120-51-4
Formula: C14H12O2
T0729
98%
Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benz
BENZYL ISOTHIOCYANATE
CAS:622-78-6
Formula: C8H7NS
T1082
98%
It is an organic compound.
BEPHENIUM HYDROXYNAPHTHOATE
CAS:3818-50-6
Formula: C28H29NO4
T0286
98%
Bephenium hydroxynaphthoate (INN, trade names Alcopara, Alcopar, Befenium, Debefenium, Francin, Nemex) is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis.
BEPOTASTINE BESILATE
CAS:190786-44-8
Formula: C21H25ClN2O3C6H6O3S
T6405
98%
Bepotastine is a non-sedating, selective antagonist of histamine 1 (H1) receptor with pIC50 of 5.7.
BERBAMINE HYDROCHLORIDE
CAS:6078-17-7
Formula: C37H42Cl2N2O6
T2920
Extracted from berberidis;Store the product in sealed, cool and dry condition
BERBERINE CHLORIDE
CAS:633-65-8
Formula: C20H18ClNO4
T0461
100%
An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.
BESIFLOXACIN HCL
CAS:405165-61-9
Formula: C19H21ClFN3O3.HCl
T6406
98%
Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic.
BESTATIN
CAS:58970-76-6
Formula: C16H24N2O4
T1257
100%
Bestatin is a competitive protease inhibitor. It is an inhibitor of aminopeptidase B, leukotriene A4 hydrolase, aminopeptidase N. It is being studied for use in the treatment of acute myelocytic leukemia.
BET BROMODOMAIN INHIBITOR
CAS:1505453-59-7
Formula: C20H15Cl2N3O2
T2072
98%
It is a BET bromodomain inhibitor
BETA-ALANINE
CAS:107-95-9
Formula: C3H7NO2
T0627
98%+
An amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A ra
BETA-CYCLODEXTRIN
CAS:7585-39-9
Formula: C42H70O35
T2951
99%
Cyclodextrins are produced from starch by means of enzymatic conversion. They are used in food, pharmaceutical,[1] drug delivery,[2] and chemical industries, as well as agriculture and environmental engineering.
BETA-HYDROXYISOVALERIC ACID
CAS:625-08-1
Formula: C5H10O3
T0613
98%
Used as pharmaceutical intermediates
BETA-LAPACHONE
CAS:4707-32-8
Formula: C15H14O3
T6407
98%
Beta-Lapachone is a selective DNA topoisomerase I inhibitor, exhibiting no inhibitory activities against DNA topoisomerase II or ligase. Phase 2.
BETA-SITOSTEROL
CAS:83-46-5
Formula: C29H50O
T2966
98%
-Sitosterol is a common plant steroid that possesses anticholesteremic properties. -Sitosterol has recently been shown to induce G2/M arrest,endoreduplication,and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways.
BETA-TETRALONE
CAS:530-93-8
Formula: C10H10O
T0660
98%+
2-Tetralone is an organic chemical compound with the molecular formula C10H10O. This colourless oil is an intermediate in organic synthesis. It is a ketone derivative of tetralin, a hydrogenated derivative of naphthalene. A related compound is 1-tetralone
BETAHISTINE DIHYDROCHLORIDE
CAS:5579-84-0
Formula: C8H14Cl2N2
T0246
99%
Betahistine is an antivertigo drug first used for treating vertigo assosicated with Mnires disease. It is also commonly used for patients with balance disorders.
BETAHISTINE MESYLATE
CAS:54856-23-4
Formula: C8H12N22(CH4O3S)
T0246L
98%
Betahistine is an antivertigo drug first used for treating vertigo assosicated with Mnires disease. It is also commonly used for patients with balance disorders.
BETAINE
CAS:107-43-7
Formula: C5H11NO2
T3243
N/A
Betaine is also known as trimethylamine, and is the quaternary ammonium derivatives of glycine and a class of N-methyl-compound or trimethyl inner salt after the hydrogen of the amino group being substituted by the methyl group.?
BETAINE HYDROCHLORIDE
CAS:590-46-5
Formula: C5H12ClNO2
T0019
98%
A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of li
BETAMETHASONE
CAS:378-44-9
Formula: C22H29FO5
T1652
98%
A glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes betamethasone particularly s
BETAMETHASONE 17-VALERATE
CAS:2152-44-5
Formula: C27H37FO6
T1163
99%
Betamethasone Valerate is a moderately potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.
BETAMETHASONE DIPROPIONATE
CAS:5593-20-4
Formula: C28H37FO7
T1559
98%
Betamethasone Dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.
BETAMIPRON
CAS:3440-28-6
Formula: C10H11NO3
T1430
98%
Betamipron is a chemical compound which is used together with panipenem to inhibit panipenem uptake into the renal tubule and prevent nephrotoxicity.
BETAXOLOL
CAS:63659-18-7
Formula: C18H29NO3
T6408
98%
Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.
BETAXOLOL HYDROCHLORIDE
CAS:63659-19-8
Formula: C18H30ClNO3
T0226
99%
A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
BETHANECHOL CHLORIDE
CAS:590-63-6
Formula: C7H17N2O2Cl
T3126
98%
Bethanechol chloride is a selective muscarinic receptor agonist without any effect on nicotinic receptors.
BETULIN
CAS:473-98-3
Formula: C30H50O2
T3121
98%
Betulin (lup-20(29)-ene-3,28-diol) is an abundant, naturally occurring triterpene. It is commonly isolated from the bark of birch trees where it forms up to 30% of the dry weight of the extractive and is found in birch sap as well.
BETULINIC ACID
CAS:472-15-1
Formula: C29H46O3
T2830
98%
Betulinic acid is a naturally occurring pentacyclic triterpenoid which has antiretroviral, antimalarial, and anti-inflammatory properties, as well as a more recently discovered potential as an anticancer agent, by inhibition of topoisomerase.
BEXAROTENE
CAS:153559-49-0
Formula: C24H28O2
T6410
98%
Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma.
BEZ235
CAS:915019-65-7
Formula: C30H23N5O
T2235
98%
BEZ235 (NVP-BEZ235, Dactolisib) is a dual ATP-competitive PI3K and mTOR inhibitor for p110a/?/d/ and mTOR(p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM in cell-free assays, respectively. Inhibits ATR with IC50 of 21 nM in 3T3TopBP1-ER cell.
BEZAFIBRATE
CAS:41859-67-0
Formula: C19H20ClNO4
T0841
98%
An antilipemic agent that lowers CHOLESTEROL and TRIGLYCERIDES. It decreases LOW DENSITY LIPOPROTEINS and increases HIGH DENSITY LIPOPROTEINS.
BG45
CAS:926259-99-6
Formula: C11H10N4O
T2294
98%
BG45 is a class I HDAC inhibitor with IC50 of 289 nM, 2.0 ?M, 2.2 ?M and >20 ?M for HDAC3, HDAC1, HDAC2, and HDAC6 in cell-free assays, respectively.
BGT226 (NVP-BGT226)
CAS:1245537-68-1
Formula: C28H25F3N6O2C4H4O4
T6072
98%
BGT226 (NVP-BGT226) is a novel class I PI3K/mTOR inhibitor for PI3Ka//? with IC50 of 4 nM/63 nM/38 nM. Phase 1/2.
BHT FCC/NF
CAS:128-37-0
Formula: C15H24O
T0935
99%
BHT is also used as an antioxidant additive in such diverse products as cosmetics, pharmaceuticals, rubber, electrical transformer oil.
BI 2536
CAS:755038-02-9
Formula: C28H39N7O3
T6173
98%
BI2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM. It shows 4- and 11-fold greater selectivity against Plk2 and Plk3. Phase 2.
BI-D1870
CAS:501437-28-1
Formula: C19H23F2N5O2
T6171
98%
BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM, respectively; 10- to 100-fold selectivity for RSK than MST2, GSK-3, MARK3, CK1 and Aurora B.
BIAPENEM
CAS:120410-24-4
Formula: C15H18N4O4S
T6411
98%
Biapenem is a carbapenem antibiotic with activity against both Gram-positive and Gram-negative bacterial strains.
BIBF 1120
CAS:656247-17-5
Formula: C31H33N5O4
T1777
95%
Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRa/ with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM in cell-free assays. Phase 3.
BIBR 1532
CAS:321674-73-1
Formula: C21H17NO3
T2380
98%
BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM in a cell-free assay.
BIBS 39
CAS:133085-33-3
Formula: C32H36N4O3
T3178
98%
BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist.
BICALUTAMIDE
CAS:90357-06-5
Formula: C18H14F4N2O4S
T0380
98%
Bicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It binds to the androgen receptor.
BIFENDATATUM
CAS:73536-69-3
Formula: C20H18O10
T3273
98%
Bifendatatum is commonly used to treat the transaminase elevation that caused by viral hepatitis and drug induced liver injury.
BIFONAZOLE
CAS:60628-96-8
Formula: C22H18N2
T1187
98%
Bifonazole is an azole antifungal drug.
BIIB-021
CAS:848695-25-0
Formula: C14H15ClN6O
T2286
98%
BIIB021(CNF2024) is an orally available, fully synthetic small-molecule inhibitor of HSP90 with Ki and EC50 of 1.7 nM and 38 nM, respectively.
BIKININ
CAS:188011-69-0
Formula: C9H9BrN2O3
T1965
98%
Bikinin(Abrasin) is a potent inhibitor of plant GSK-3/Shaggy-like kinase; activates BR signaling downstream of the BR receptor.
BILIRUBIN
CAS:635-65-4
Formula: C33H36N4O6
T2934
98%
Extracted?from?bezoar;Store?the?product?in?sealed,?cool?and?dry?condition
BILOBALIDE
CAS:33570-04-6
Formula: C15H18O8
T2808
98%
Bilobalide, a bioactive from Gingko biloba,is active on hypoxia induced alterations
BIMATOPROST
CAS:155206-00-1
Formula: C25H37NO4
T2538
99%
Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.
BINDARIT
CAS:130641-38-2
Formula: C19H20N2O3
T6413
98%
Bindarit exhibits selective inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.
BIO
CAS:667463-62-9
Formula: C16H10BrN3O2
T1917
98%
BIO is a specific inhibitor of GSK-3 with IC50 of 5 nM for GSK-3a/ in a cell-free assay, shows >16-fold selectivity over CDK5, also a pan-JAK inhibitor.
BIOCHANIN A
CAS:491-80-5
Formula: C16H12O5
T2859
98%
Biochanin A, an O-methylated isoflavone from Trifolium pratense, inhibits protein tyrosine kinase (PTK) of epidermal growth factor receptor with IC50 values of 91.5 M.
BIOTIN
CAS:58-85-5
Formula: C10H16N2O3S
T1116
98%
Biotin is a water-soluble B-vitamin and is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.
BIOYMIFI
CAS:1420071-30-2
Formula: C22H12BrN3O4S
T2065
98%
bioymifi can act as a single agent to induce DR5 clustering and aggregation, leading to apoptosis
BIPERIDEN
CAS:514-65-8
Formula: C21H29NO
T0218
90%
A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms i
BIRB 796
CAS:285983-48-4
Formula: C31H37N5O3
T6277
98%
BIRB 796 (Doramapimod) is a highly selective p38a MAPK inhibitor with Kd of 0.1 nM, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2, ZAP-70, EGFR, HER2, PKA, PKC, PKCa//?.
BIRCH-ME
CAS:119-36-8
Formula: C8H8O3
T0399
99%
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. It is also synthetically produced, used as a fragrance, in foods and beverages, and in liniments.
BIRINAPANT
CAS:1260251-31-7
Formula: C42H56F2N8O6
T6007
98%
Birinapant is a SMAC mimetic antagonist, mostly to cIAP1 with Kd of <1 nM, less potent to XIAP. Phase 2.
BIS(2-CHLOROETHYL)AMINE HYDROCHLORIDE
CAS:821-48-7
Formula: C4H9Cl2NHCl
T0565
98%+
Pharmaceutical Intermediates
BIS(4-CYANOPHENYL)METHANOL
CAS:134521-16-7
Formula: C15H10N2O
T0534
95%
Used as organic synthesis and medicine intermediate.
BISMUTH SUBSALICYLATE
CAS:14882-18-9
Formula: C7H5BiO4
T0424
99%
Bismuth subsalicylate is used to treat diarrhea in adults and teenagers. It is also used to relieve the symptoms of an upset stomach, such as heartburn, indigestion, and nausea in adults and teenagers.
BISOCTRIZOLE
CAS:103597-45-1
Formula: C41H50N6O2
T0340
99%
Bisoctrizole is a benzotriazole-based organic compound that is added to sunscreens to absorb UV rays.
BISOPROLOL FUMARATE
CAS:104344-23-2
Formula: C20H33NO6
T0143
99%
A cardioselective beta-1 adrenergic blocker. It is effective in the management of HYPERTENSION and ANGINA PECTORIS.
BISPYRAZOLONE
CAS:7477-67-0
Formula: C20H18N4O2
T0659
98%
Bispyrazolone is white or light yellow crystalline powder.
BITHIONOL
CAS:97-18-7
Formula: C12H6Cl4O2S
T0830
97%
Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDAs for bithionol drug products were withdrawn on Octobe
BIX 01294
CAS:1392399-03-9
Formula: C28H38N6O23HCl
T1959
98%
BIX01294 is an inhibitor of G9a histone methyltransferase with IC50 of 2.7 M in a cell-free assay, reduces H3K9me2 of bulk histones, also weakly inhibits GLP (primarily H3K9me3), no significant activity observed at other histone methyltransferases.
BIX 02188
CAS:1094614-84-2
Formula: C25H24N4O2
T6324
98%
BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK5 catalytic activity with IC50 of 810 nM, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.
BIX02189
CAS:1094614-85-3
Formula: C27H28N4O2
T2416
98%
BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM, also inhibits ERK5 catalytic activity with IC50 of 59 nM in cell-free assays, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.
BLEOMYCIN SULFATE
CAS:9041-93-4
Formula: C55H85N17O25S4
T6116
98%
Bleomycin Sulfate is a glycopeptide antibiotic and an anticancer agent for squamous cell carcinomas (SCC) with IC50 of 4 nM in UT-SCC-19A cells.
BLONANSERIN
CAS:132810-10-7
Formula: C23H30FN3
T1180
99%
Blonanserin is a novel atypical antipsychotic agent with potent dopamine D2 and serotonin 5-HT2 receptors antagonist properties.
BLU9931
CAS:1538604-68-0
Formula: C26H22Cl2N4O3
T2347
98%
BLU9931 is the first selective small molecule inhibitor of FGFR4 with IC50 of 3 nM; less potent for FGFR1/2/3(IC50> 150 nM).
BLUTENE CHLORIDE
CAS:92-31-9
Formula: C15H16ClN3S
T0312
85%
A phenothiazine that has been used as a hemostatic, a biological stain, and a dye for wool and silk. Tolonium chloride has also been used as a diagnostic aid for oral and gastric neoplasms and in the identification of the parathyroid gland in thyroid surg
BLZ945
CAS:953769-46-5
Formula: C20H22N4O3S
T6119
98%
BLZ945 is an orally active, potent and selective CSF-1R inhibitor with IC50 of 1 nM, >1000-fold selective against its closest receptor tyrosine kinase homologs.
BMH-21
CAS:896705-16-1
Formula: C21H20N4O2
T1767
98%
BMH-21 is a small molecule DNA intercalator that binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription; does not cause phosphorylation of H2AX.
BML-190
CAS:2854-32-2
Formula: C23H23ClN2O4
T6417
98%
BML-190 is a selective cannabinoid CB2 receptor inverse agonist with Ki of 435 nM, with 50-fold selectivity over CB1 receptor.
BML-210
CAS:537034-17-6
Formula: C20H25N3O2
T3204
98%
BML-210 is the novel HDAC inhibitor, and its mechanism of action has not been characterized.
BML-277
CAS:516480-79-8
Formula: C20H14ClN3O2
T2033
98%
BML-277 (C 3742) is a selective Chk2 (checkpoint kinase 2) inhibitor with an IC50 of 15 nM.
BMS 777607
CAS:1025720-94-8
Formula: C25H19ClF2N4O4
T2699
100%
BMS-777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50 of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM in cell-free assays, 40-fold more selective for Met-related targets versus Lck, VEGFR-2, and TrkA/B, and more than 500-fold greater selectiv
BMS-265246
CAS:582315-72-8
Formula: C18H17F2N3O2
T2679
100%
BMS-265246 is a potent and selective CDK1/2 inhibitor with IC50 of 6 nM/9 nM in a cell-free assay. It is 25-fold more selective for CDK1/2 than CDK4.
BMS-303141
CAS:943962-47-8
Formula: C19H15Cl2NO4S
T2337
98%
BMS-303141 is a potent ATP-citrate lyase (ACL) inhibitor with IC50 value of 0.13 uM (human recombinant ACL).
BMS-345541
CAS:445430-58-0
Formula: C14H17N5
T6326
98%
BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 M and 4 M, respectively.
BMS-378806
CAS:357263-13-9
Formula: C22H22N4O4
T6418
98%
BMS-378806 selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.
BMS-536924
CAS:468740-43-4
Formula: C25H26ClN5O3
T6419
98%
BMS-536924 is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for Akt1, MAPK1/2.
BMS-599626
CAS:714971-09-2
Formula: C27H27FN8O3
T2610
99%
AC480 (BMS-599626) is a selective and efficacious inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM, ~8-fold less potent to HER4, >100-fold to VEGFR2, c-Kit, Lck, MET etc. Phase 1.
BMS-707035
CAS:729607-74-3
Formula: C17H19FN4O5S
T6420
98%
BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.
BMS-754807
CAS:1001350-96-4
Formula: C23H24FN9O
T2349
98%
BMS-754807 is a potent and reversible inhibitor of IGF-1R/InsR with IC50 of 1.8 nM/1.7 nM in cell-free assays, less potent to Met, Aurora A/B, TrkA/B and Ron, and shows little activity to Flt3, Lck, MK2, PKA, PKC etc. Phase 2.
BMS-794833
CAS:1174046-72-0
Formula: C23H15ClF2N4O3
T2419
98%
BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7 nM/15 nM, also inhibits Ron, Axl and Flt3 with IC50 of <3 nM; a prodrug of BMS-817378. Phase 1.
BMS-833923
CAS:1059734-66-5
Formula: C30H27N5O
T2299
98%
BMS-833923 is an orally bioavailable Smoothened antagonist. Phase 2.
BMY 7378 2HYDROCHLORIDE
CAS:21102-95-4
Formula: C22H33Cl2N3O3
T3046
99%
BMY-7,378 is a 5-HT1A receptor weak partial agonist/antagonist and a1D-adrenergic receptor antagonist.
BOHEMINE
CAS:189232-42-6
Formula: C18H24N6O
T2029
98%
Bohemine is a cyclin-dependent kinase inhibitor.
BOLDENONE UNDECYLENATE
CAS:13103-34-9
Formula: C30H44O3
T3137
99%
Boldenone undecylenate(Equipoise) is a synthetic steroid which has a similar effect as the natural steroid testosterone; it is frequently used in veterinary medicine, though it is also used in humans.
BORNEOL
CAS:507-70-0
Formula: C10H18O
T3038
98%
Extracted from Cinnamomum cassia;Suitability:Ethanol,ether,petroleum ether,benzene,toluene,acetone,decalin,tetralin;Store the product in sealed,cool and dry condition
BORNYL ACETATE
CAS:76-49-3
Formula: C12H20O2
T1246
98%
Bornyl acetate is the main volatile constituent in numerous conifer oils and some Chinese traditional herbs, which has displayed an anti-inflammatory effect before.
BORTEZOMIB
CAS:179324-69-7
Formula: C19H25BN4O4
T2399
98%
Bortezomib (PS-341) is a potent 20S proteasome inhibitor with Ki of 0.6 nM in a cell-free assay.
BOSENTAN
CAS:147536-97-8
Formula: C27H29N5O6S
T6264
98%
Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.
BOSENTAN HYDRATE
CAS:157212-55-0
Formula: C27H29N5O6SH2O
T6265
98%
Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.
BOSUTINIB
CAS:380843-75-4
Formula: C26H29Cl2N5O3
T0152
99%
Bosutinib is a Bcr-Abl kinase inhibitor for the treatment of Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML). Compared to other tyrosine kinase inhibitors, it has a more favourable hematologic toxicity profile. FDA approved on Se
BOVINOCIDIN
CAS:504-88-1
Formula: C3H5NO4
T3009
97%
A new antibiotic bovinocidin, identified as beta-nitropropionic acid.
BPR1J-097
CAS:1327167-19-0
Formula: C27H28N6O3S
T2272
98%
BPR1J-097 is a novel small molecule FLT-3 inhibitor(IC50=117 nM) with promising in vivo anti-tumour activities; inhibits FLT-3 D835Y with an IC50 of 3 nM.
BQU57
CAS:1637739-82-2
Formula: C16H13F3N4O
T2267
98%
BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth similar to depletion of Ral by siRNA. The IC50 for BQU57 of 2.0 _mu_M in H2122 and 1.3 _mu_M in H358.
BRASSINOLIDE
CAS:72962-43-7
Formula: C28H48O6
T3151
98%
Brassinolide is a plant hormone. The first isolated brassinosteroid, it was discovered when it was shown that pollen from rapeseed (Brassica napus) could promote stem elongation and cell division.
BRD4770
CAS:1374601-40-7
Formula: C25H23N3O3
T1923
98%
BRD4770 is a histone methyltransferase G9a inhibitor with IC50 of 6.3 M, and induces cell senescence.
BRD73954
CAS:1440209-96-0
Formula: C16H16N2O3
T6421
98%
BRD73954 ia a potent and selective HDAC inhibitor with IC50 of 36 nM and 120 nM for HDAC6 and HDAC8, respectively.
BRD7716
CAS:329059-55-4
Formula: C28H36N2O4S
T2353
98%
BRD7116 competitively binds to bacterial DNA gyrase, exhibits an EC50 of 200 nM for LSCe cells, with cell-non-autonomous anti-leukemia activity.
BREFELDIN A
CAS:20350-15-6
Formula: C16H24O4
T6062
98%
Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 M in HCT 116 cells, induces cancer cell differentiation and apoptosis.
BREVIANAMIDE F
CAS:38136-70-8
Formula: C16H17N3O2
T3208
98%
Brevianamide F , also known as cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines. It is the simplest member and the biosynthetic precursor of a large family of biologically active prenylated tryptophan-proline 2,5-diketo
BREVISCAPIN
CAS:116122-36-2
Formula: C21H18O11
T3242
N/A
Breviscapine, is the total flavonoid components (the content of scutellarin > or =85%) extracted from the dried whole plant of Erigeron breviscapus
BREXPIPRAZOLE
CAS:913611-97-9
Formula: C25H27N3O2S
T2306
98%
Brexpiprazole is a novel D2 dopamine partial agonist.
BRICICLIB
CAS:865783-99-9
Formula: C19H23O10PS
T3207
98%
Briciclib is a small molecule that suppresses cyclin D1 accumulation in cancer cells.
BRIMONIDINE TARTRATE
CAS:70359-46-5
Formula: C15H16BrN5O6
T6422
98%
Brimonidine Tartrate is a highly selective a-adrenergic receptor agonist with EC50 of 0.45 nM for the a2A adrenoreceptor, and used to treat open-angle glaucoma or ocular hypertension.
BRINZOLAMIDE
CAS:138890-62-7
Formula: C12H21N3O5S3
T0142
99%
Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase inhibitor. Carbonic anhydrase (CA) is an enzyme found in many tissues of the body including the eye. It catalyzes the reversible reaction involving the hydration of carbon d
BRIVANIB
CAS:649735-46-6
Formula: C19H19FN4O3
T6036
98%
Brivanib is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-. Phase 3.
BRIVANIB ALANINATE
CAS:649735-63-7
Formula: C22H24FN5O4
T2576
98%
Brivanib alaninate (BMS-582664) is the prodrug of BMS-540215, an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM.
BRIVUDINE
CAS:69304-47-8
Formula: C11H13BrN2O5
T0718
98%
Brivudine is an antiviral drug used in the treatment of herpes zoster.
BRL 54443
CAS:57477-39-1
Formula: C14H18N2O
T2459
99%+
BRL 54443 is a 5-HT1E and 5-HT1F receptor agonist with pKi of 8.7 and 9.25, respectively, with a weak binding affinity for 5-HT1A, 5-HT1B, 5-HT1D receptors.
BRL-15572
CAS:193611-72-2
Formula: C25H27ClN2O2HCl
T6423
98%
BRL-15572 is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B receptor.
BROMFENAC SODIU
CAS:120638-55-3
Formula: C15H11BrNNaO3
T2403
92%
Bromfenac Sodium is the sodium salt form of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory activities. Upon ophthalmic administration, bromfenac binds to and inhibits the activity of cyclooxygenase II (COX II
BROMHEXINE HYDROCHLORIDE
CAS:611-75-6
Formula: C14H21Br2ClN2
T0828
99%
A mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.
BROMHEXINE IMPURITY B
CAS:50910-55-9
Formula: C7H5Br2NO
T1690
98%+
Quinolones used as MRS inhibitors and bactericides
BROMINDIONE
CAS:1146-98-1
Formula: C15H9BrO2
T1515
98%
Bromindione is a new anticoagulant.
BROMISOVAL
CAS:496-67-3
Formula: C6H11BrN2O2
T0227
98%
Bromisoval is a sedative and mild hypnotic with potentially toxic effects.
BROMOPRIDE
CAS:4093-35-0
Formula: C14H22BrN3O2
T1175
99%
Bromopride is a dopamine antagonist with prokinetic properties closely related to metoclopramide, and is widely used as an antiemetic. It is not available in the United States or the United Kingdom.
BROMOSPORINE
CAS:1619994-69-2
Formula: C17H20N6O4S
T6255
98%
Bromosporine is a broad spectrum inhibitor for bromodomains with IC50 of 0.41 M, 0.29 M, 0.122 M and 0.017 M for BRD2, BRD4, BRD9 and CECR2, respectively.
BROMPHENIRAMINE MALEATE
CAS:980-71-2
Formula: C16H19BrN2C4H4O4
T0205
99%
Brompheniramine hydrogen maleate is a histamine H1 receptors antagonist.
BRONOPOL
CAS:52-51-7
Formula: C3H6NO4Br
T0880
98%
Bronopol is a Standardized Chemical Allergen. The physiologic effect of bronopol is by means of Increased Histamine Release and Cell-mediated Immunity. The chemical classification of bronopol is Allergens.
BROXYQUINOLINE
CAS:521-74-4
Formula: C9H5Br2NO
T0701
98%
Broxyquinoline is an antiprotozoal agent and able to release oxygen free radicals from the water in mucous membranes.
BS-181 HCL
CAS:1092443-52-1
Formula: C22H32N6
T1947
98%
BS-181 is a highly selective CDK7 inhibitor with IC50 of 21 nM. ; >40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9.
BTZ043 RACEMATE
CAS:957217-65-1
Formula: C17H16F3N3O5S
T6425
98%
BTZ043 racemate is a decaprenylphosphoryl--D-ribose 2'-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis.
BUCETIN
CAS:1083-57-4
Formula: C12H17NO3
T0442
98%
Bucetin is a pharmaceutical drug that acts as an analgesic and antipyretic. Chemically, it is similar to phenacetin with which it shares the risk of carcinogenesis. Bucetin was withdrawn from use in 1986 due to renal toxicity
BUCLADESINE SODIUM SALT
CAS:16980-89-5
Formula: C18H23N5O8PNa
T1418
95%
A cyclic nucleotide derivative that mimics the action of endogenous CYCLIC AMP and is capable of permeating the cell membrane. It has vasodilator properties and is used as a cardiac stimulant. (From Merck Index, 11th ed)
BUDESONIDE
CAS:51333-22-3
Formula: C25H34O6
T0094
98%
Budesonide is an anti-inflammatory corticosteroid.Budesonide has shown the potent glucocorticoid activity and little mineralocorticoid activity. In addition, Budesonide has been reported to have a wide range of inhibitory activities against multiple cells
BUFALIN
CAS:465-21-4
Formula: C24H34O4
T1719
98%
Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potential cardiotonic and antineoplastic a
BUFEXAMAC
CAS:2438-72-4
Formula: C12H17NO3
T0867
95%
Bufexamac is a COX inhibitor for IFN-a release.
BUFLOMEDIL HYDROCHLORIDE
CAS:35543-24-9
Formula: C17H26ClNO4
T0317
98%
Buflomedil hydrochloride is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease.
BULLEYACONITINE A
CAS:107668-79-1
Formula: C35H49NO9
T3021
98%
Bulleyaconitine A is an analgesic and antiinflammatory drug isolated from Aconitum plants; has several potential targets, including voltage-gated Na+ channels. Extracted from Aconitumkusnezoffii Reichb.;Suitability:Ethanol,chloroform,ether;Store the produ
BUMETANIDE
CAS:28395-03-1
Formula: C17H20N2O5S
T0108
98%
Bumetanide is a Loop Diuretic. The physiologic effect of bumetanide is by means of Increased Diuresis at Loop of Henle.
BUPIVACAINE HYDROCHLORIDE
CAS:18010-40-7
Formula: C18H28N2OHCl
T0030
98%
Bupivacaine hydrochloride binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, used for treating cardiac arrhythmias. Bupivacaine Hydrochloride is a local anaesthetic drug belonging to the amino am
BUPROPION HYDROCHLORIDE
CAS:31677-93-7
Formula: C13H19Cl2NO
T1150
99%
A unicyclic, aminoketone antidepressant. The mechanism of its therapeutic actions is not well understood, but it does appear to block dopamine uptake. The hydrochloride is available as an aid to smoking cessation treatment.
BUSPIRONE HYDROCHLORIDE
CAS:33386-08-2
Formula: C21H32ClN5O2
T2132
98%
An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
BUSULFAN
CAS:55-98-1
Formula: C6H14O6S2
T0923
98%
Antineoplastic bifunctional, DNA alkylating agent that causes DNA damage by cross-linking DNA and proteins. Causes double-base lesions mainly at 5'-GA-3' and, to a lesser extent, at 5'-GG-3' sequences. Forms an intrastrand cross-link at the 5'-GA-3' seque
BUTAMBEN
CAS:94-25-7
Formula: C11H15NO2
T0916
98%
It is the ester of 4-aminobenzoic acid and butanol. It's of Low Solubility , and It's been reported that it's more Effective than its corresponding Ethyl Ester When applied to intact Mucous Membrane
BUTEIN
CAS:487-52-5
Formula: C15H12O5
T6427
98%
Butein, a plant polyphenol isolated from Rhus verniciflua, is able to inhibit the activation of protein tyrosine kinase, NF-?B and STAT3, also inhibits EGFR
BUTENAFINE HYDROCHLORIDE
CAS:101827-46-7
Formula: C23H27NHCl
T1217
99%
Butenafine hydrochloride is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.
BUTOCONAZOLE NITRATE
CAS:64872-77-1
Formula: C19H18Cl3N3O3S
T1438
98%
Butoconazole is an imidazole antifungal used in gynecology.
BUTYL BENZYL PHTHALATE
CAS:85-68-7
Formula: C19H20O4
T0640
98%+
It is mostly used as a plasticizer for PVC. It is considered a toxicant.
BUTYLHYDROXYANISOLE
CAS:25013-16-5
Formula: C11H16O2
T0787
98%
Butylated hydroxyanisole (BHA) is an antioxidant consisting of a mixture of two isomeric organic compounds, 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.
BUTYLPARABEN
CAS:94-26-8
Formula: C11H14O3
T0927
99%
Butylparaben is a Standardized Chemical Allergen. The physiologic effect of butylparaben is by means of Increased Histamine Release and Cell-mediated Immunity. The chemical classification of butylparaben is Allergens.
BUXAMINE
CAS:924-49-2
Formula: C4H9NO3
T0028
98%
Agent for improving learning or memory [US6803366]Gamma Hydroxybutyric Acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple countries. It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem.
BV-6
CAS:1001600-56-1
Formula: C70H96N10O8
T6428
98%
BV-6 is a SMAC mimetic, dual cIAP and XIAP inhibitor.
BVT 2733
CAS:376640-41-4
Formula: C17H21ClN4O3S2
T2057
98%
BVT 2733 is a new, small molecule, non-steroidal, isoform-selective inhibitor of 11beta-hydroxysteroid dehydrogenase type 1 (11-HSD1).
BX-912
CAS:702674-56-4
Formula: C20H23BrN8O
T1837
98%
BX-912 is a selective inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1) with IC50 of 12 nM; >10 fold selectivity over PKA, PKC, C-Kit, EGFR etc.
BX471(ZK-811752)
CAS:217645-70-0
Formula: C21H24ClFN4O3
T2375
98%
BX471 is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1); exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.
BX795
CAS:702675-74-9
Formula: C23H26IN7O2S
T1830
98%
BX795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, 140- and 1600-fold more selective for PDK1 than PKA and PKC in cell-free assays, respectively. Meanwhile, in comparison to GSK3 more than 100-fold selectivity observed for PDK1.
BYL-719
CAS:1217486-61-7
Formula: C19H22F3N5O2S
T1921
98%
Alpelisib (BYL719) is a potent and selective PI3Ka inhibitor with IC50 of 5 nM in a cell-free assay, and minimal effect on PI3K/?/d. Phase 2.
C-DIM12(1,1-BIS (3'-INDOLYL)-1-(P-CHLOROPHENYL) METHANE)
CAS:178946-89-9
Formula: C23H17ClN2
T3106
98%
C-DIM12 induced expression of Nurr1-regulated genes that was abolished by Nurr1 knockdown. C-DIM12 increased expression of transfected human Nurr1, induced Nurr1 protein expression in primary dopaminergic neurons and enhanced neuronal survival from exposure to 6-OHDA.
C646
CAS:328968-36-1
Formula: C24H19N3O6
T2452
98%
C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM in a cell-free assay. Preferentially selective for p300 versus other acetyltransferases.
C7280948
CAS:587850-67-7
Formula: C14H16N2O2S
T2097
98%
C-7280948 is a PRMT1 inhibitor.
CABAZITAXEL
CAS:183133-96-2
Formula: C45H57NO14
T2543
99%
Cabazitaxel(XRP6258; RPR-116258A) is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.
CABOTEGRAVIR (GSK744, GSK1265744)
CAS:1051375-10-0
Formula: C19H17F2N3O5
T6098
98%
Cabotegravir (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor against a broad range of HIV subtypes, and inhibits the HIV-1 integrase catalyzed strand transfer reaction with IC50 of 3.0 nM. Phase 2.
CABOZANTINIB
CAS:849217-68-1
Formula: C28H24FN3O5
T2586
100%
Cabozantinib (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively.
CABOZANTINIB S-MALATE
CAS:1140909-48-3
Formula: C32H30FN3O10
T1797
98%
Cabozantinib S-malate is the s-malate salt form of cabozantinib, an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Cabozantinib strongly binds to and inhibits several RTKs, which are
CAFFEIC ACID
CAS:331-39-5
Formula: C9H8O4
T2807
99%
Extracted from Solidago decurrens,large-fruited Chinese hawthorn;Suitability:Hot water and cold ethanol;Store the product in sealed,cool and dry condition
CAL-101
CAS:870281-82-6
Formula: C22H18FN7O
T1894
98%
CAL-101 (Idelalisib, GS-1101) is a selective p110d inhibitor with IC50 of 2.5 nM; shown to have 40- to 300-fold greater selectivity for p110d than p110a//?, and 400- to 4000-fold more selectivity to p110d than C2, hVPS34, DNA-PK and mTOR.
CALCIFEDIOL
CAS:19356-17-3
Formula: C27H44O2
T6430
98%
Calcifediol is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 M. It also suppresses PTH secretion and mRNA (ED50=2 nM).
CALCITRIOL
CAS:32222-06-3
Formula: C27H44O3
T6316
98%
Calcitriol is the hormonally active form of vitamin D.
CALCIUM FOLINATE
CAS:1492-18-8
Formula: C20H21CaN7O7
T0148
99%
Calcium Levofolinate is a calcium salt of folinic acid that is an adjuvant used in cancer chemotherapy.
CALCIUM LEVOFOLINATE
CAS:80433-71-2
Formula: C20H21N7O7Ca
T6431
98%
Calcium Levofolinate is a calcium salt of folinic acid that is an adjuvant used in cancer chemotherapy.
CALPAIN INHIBITOR III
CAS:88191-84-8
Formula: C22H26N2O4
T2470
76%
Calpain Inhibitor III is a Cysteine protease.
CALPEPTIN
CAS:117591-20-5
Formula: C20H30N2O4
T6432
98%
Calpeptin is a potent, cell-permeable calpain inhibitor with ID50 of 52 nM, 34 nM, 138 nM, and 40 nM for Calpain I (porcine erythrocytes), Calpain II (porcine kidney), Papainb, and Calpain I (human platelets), respectively.
CAMKP INHIBITOR
CAS:52789-62-5
Formula: C10H12NNaO9S2
T2159
87%
It is a CaMKP Inhibitor.
CAMOSTAT MESYLATE
CAS:59721-29-8
Formula: C21H26N4O8S
T2391
98%
Camostat is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.
Campathecin
CAS:7689-03-4
Formula: C20H16N2O4
T1123
An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
CAMPHOR
CAS:76-22-2
Formula: C10H16O
T2952
96%
Camphor is a bicyclic monoterpene ketone found widely in plants, especially CINNAMOMUM CAMPHORA. It is used topically as a skin antipruritic and as an anti-infective agent.
CAMYLOFINE 2HYDROCHLORIDE
CAS:54-30-8
Formula: C19H32N2O22HCl
T0346
98%
Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
CANAGLIFLOZIN
CAS:842133-18-0
Formula: C24H25FO5S
T1782
98%
Canagliflozin(JNJ 28431754; TA 7284) is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM, exhibits 413-fold selectivity over hSGLT1.
CANDESARTAN
CAS:139481-59-7
Formula: C24H20N6O3
T1461
97%
Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, duri
CANDESARTAN CILEXETIL
CAS:145040-37-5
Formula: C33H34N6O6
T2400
98%
Candesartan Cilexetil is an angiotensin II receptor antagonist with IC50 of 0.26 nM, used in the treatment of hypertension.
CANERTINIB (CI-1033)
CAS:267243-28-7
Formula: C24H25ClFN5O3
T6136
98%
Canertinib (CI-1033) is a pan-ErbB inhibitor for EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM, no activity to PDGFR, FGFR, InsR, PKC, or CDK1/2/4. Phase 3.
CANERTINIB DIHYDROCHLORIDE
CAS:289499-45-2
Formula: C24H27Cl3FN5O3
T2501
100%
Canertinib Dihydrochloride is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and radiosensitizing activities. Canertinib binds to the intracellular domains of epidermal growth factor receptor tyrosine kinases (
CANRENONE
CAS:976-71-6
Formula: C22H28O3
T0354
98%
A synthetic pregnadiene compound with anti-aldosterone activity.
CANTHARIDIN
CAS:56-25-7
Formula: C10H12O4
T2903
98%
Extracted from (Meloidae),Mylabris phalerata Pallas,Mylabris cichorii L.de; Suitability:Acetone,chloroform,ether and ethyl acetate;Store the product in sealed,cool and dry condition
CAPASTAT SULFATE
CAS:1405-37-4
Formula: C25H46N14O12S
T1441
90%
Capreomycin Sulfate is a cyclic peptide antibiotic and thought to inhibit protein synthesis by binding to the 70S ribosomal unit.
CAPECITABINE
CAS:154361-50-9
Formula: C15H22FN3O6
T1408
98%
Prodrug of 5-Fluorouracil (5-FU). Selectively activated in tumor cells by thymidine phosphorylase; inhibits DNA synthesis upon conversion to 5-FU. Orally available.
CAPSAICIN
CAS:404-86-4
Formula: C18H27NO3
T1062
Capsaicin is an active component of chili peppers. It selectively binds to TRPV1 which is a heat-activated calcium channel. Capsaicin causes the channel to open below 37 C This is why capsaicin is linked to the sensation of heat.
CAPTOPRIL
CAS:62571-86-2
Formula: C9H15NO3S
T1462
99%
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhib
CARAZOLOL
CAS:57775-29-8
Formula: C18H22N2O2
T3284
98%
Carazolol?is a high affinityantagonist/partial inverse agonist (also referred to as abeta blocker) of the -adrenergic receptor.
CARBADOX
CAS:6804-07-5
Formula: C11H10N4O4
T0770
An antibacterial agent that has been used in veterinary practice for treating swine dysentery and enteritis and for promoting growth. However, its use has been prohibited in the UK following reports of carcinogenicity and mutagenicity. (From Martindale
CARBAGLU
CAS:1188-38-1
Formula: C6H10N2O5
T0755
98%
Carglumic acid is an orphan drug used for the treatment of hyperammonaemia in patients with N-acetylglutamate synthase deficiency. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood-brain barrier a
CARBAMAZEPINE
CAS:298-46-4
Formula: C15H12N2O
T0943
97%
An anticonvulsant used to control grand mal and psychomotor or focal seizures. Its mode of action is not fully understood, but some of its actions resemble those of PHENYTOIN; although there is little chemical resemblance between the two compounds, their
CARBAMOYLCHOLINE CHLORIDE
CAS:51-83-2
Formula: C6H15ClN2O2
T0105
98%
A slowly hydrolyzed cholinergic agonist that acts at both muscarinic and nicotinic receptors.
CARBARYL
CAS:63-25-2
Formula: C12H11NO2
T0790
100%
A carbamate insecticide and parasiticide. It is a potent anticholinesterase agent belonging to the carbamate group of reversible cholinesterase inhibitors. It has a particularly low toxicity from dermal absorption and is used for control of head lice in s
CARBAZOCHROME SODIUM SULFONATE
CAS:51460-26-5
Formula: C10H17N4NaO8S
T0852
97%
Carbazochrome sodium sulfonate (AC-17) is an antihemorrhagic for use in the treatment of hemorrhoids
CARBENDAZIM
CAS:10605-21-7
Formula: C9H9N3O2
T3124
98%
Carbendazim is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities.
CARBENICILLIN DISODIUM
CAS:4800-94-6
Formula: C17H16N2Na2O6S
T1143
90%
Carbenicillin inhibits the cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidase on the inner surface of the bacterial cell membrane. Carbenicillin is a white to slightly yellow, hygroscopic powder soluble in water and in alcoho
CARBENOXOLONE DISODIUM
CAS:7421-40-1
Formula: C34H48Na2O7
T0992
98%
An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity.
CARBETAPENTANE CITRATE
CAS:23142-01-0
Formula: C20H31NO37C6H8O7
T0464
98%
Pentoxyverine Citrate is an antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold.
CARBIDOPA HYDRATE
CAS:38821-49-7
Formula: C10H16N2O5
T2148
98%
An inhibitor of DOPA decarboxylase, preventing conversion of levodopa to dopamine. It is used in parkinson disease to reduce peripheral adverse effects of levodopa. It has no antiparkinson actions by itself.
CARBIMAZOLE
CAS:22232-54-8
Formula: C7H10N2O2S
T0952
98%
An imidazole antithyroid agent. Carbimazole is metabolized to METHIMAZOLE, which is responsible for the antithyroid activity.
CARBINOXAMINE MALEATE SALT
CAS:3505-38-2
Formula: C20H23ClN2O5
T2222
98%
Carbinoxamine maleate is used as Histamine H1 Antagonists.
CARBOPLATIN
CAS:41575-94-4
Formula: C6H12N2O4Pt
T1058
99%
An organoplatinum compound that possesses antineoplastic activity.
CARDAMONI
CAS:19309-14-9
Formula: C16H14O4
T2994
100%
Cardamomin (also known as cardamonin) is a chalconoid that has been isolated from several plants including Alpinia katsumadai and Alpinia conchigera. It has received growing attention from the scientific community due to the expectations toward its benefi
CARDIOGENOL C HYDROCHLORIDE
CAS:671225-39-1
Formula: C13H17ClN4O2
T2161
98%
Small molecule cardiogenol C upregulates cardiac markers and induces cardiac functional properties in lineage-committed progenitor cells.
CARFILZOMIB
CAS:868540-17-4
Formula: C40H57N5O7
T1795
98%
Carfilzomib is an epoxomicin derivate with potential antineoplastic activity. Carfilzomib irreversibly binds to and inhibits the chymotrypsin-like activity of the 20S catalytic core subunit of the proteasome, a protease complex responsible for degradin
CARIPORIDE
CAS:159138-80-4
Formula: C12H17N3O3S
T2238
98%
Cariporide (HOE-642), a potent NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activation of the GPIIb/IIIa receptor (PAC-1).
CARISOPRODOL
CAS:78-44-4
Formula: C12H24N2O4
T1074
98%
A centrally acting skeletal muscle relaxant whose mechanism of action is not completely understood but may be related to its sedative actions. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful musc
CARMOFUR
CAS:61422-45-5
Formula: C11H16FN3O3
T1307
98%
Carmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
CARMUSTINE
CAS:154-93-8
Formula: C5H9Cl2N3O2
T3091
98%
Carmustine is a cell-cycle phase nonspecific alkylating antineoplastic agent.
CARPROFEN
CAS:53716-49-7
Formula: C15H12ClNO2
T1325
98%
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Carprofen was previously used in human medicine for over 10 years (1985-1995). It w
CARSALAM
CAS:2037-95-8
Formula: C8H5NO3
T0258
98%
CARSALAM is an organic compound.
CARTEOLOL HYDROCHLORIDE
CAS:51781-21-6
Formula: C16H24N2O3HCl
T1282
100%
A beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.
CARVEDILOL
CAS:72956-09-3
Formula: C24H26N2O4
T0447
98%
Carvedilol is a non-selective beta blocker/alpha-1 blocker with an IC50 of 3.8 M for inhibition of LDL oxidation.
CARVEDILOL EP IMPURITY E
CAS:64464-07-9
Formula: C9H13NO2HClXH2O
T1698
99%
Used as pharmaceutical intermediates
CARVEDILOL PHOSPHATE
CAS:610309-89-2
Formula: C24H26N2O4H2OH3O4P
T0342
99%
Carvedilol is a non-selective beta blocker indicated in the treatment of mild to moderate congestive heart failure (CHF). It blocks beta-1 and beta-2 adrenergic receptors as well as the alpha-1 adrenergic receptors.
CARYOPHYLLENE OXIDE
CAS:1139-30-6
Formula: C14H22O
T2724
95%
Caryophyllene oxide, isolated from Aegle marmelos, has the potent anti-inflammatory activity.
CARZENIDE
CAS:138-41-0
Formula: C7H7NO4S
T0398
97%
A white powder.
CASANTHRANOL
CAS:8024-48-4
Formula: C21H22O10
T0771
98%
Dried aged bark of a buckthorn, Frangula purshiana (FRANGULA), that contains the anthraquinone EMODIN and cascarosides. It is used as a laxative (CATHARTICS).
CASPOFUNGIN ACETATE
CAS:179463-17-3
Formula: C56H96N10O19
T1799
98%
Caspofungin Acetate is the acetate salt of an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. Caspofungin inhibits 1,3-beta-glucan synthase, resulting in decreased synthesis of b
CATALPOL
CAS:2415-24-9
Formula: C15H22O10
T2780
98%
The primary function is to stimulate the production of adrenal cortical hormones,which increases the production of sex hormones. Catalpol also exhibits anti-inflammatory activity and has shown to increase the production of androgens yielded by the adrena
CATECHIN
CAS:154-23-4
Formula: C15H14O6
T0822
95%
Catechin is a flavan-3-ol, a type of natural phenol and antioxidant. It is a plant secondary metabolite. It belongs to the group of flavan-3-ols (or simply flavanols), part of the chemical family of flavonoids.
CATHARANTHINE
CAS:2468-21-5
Formula: C21H24N2O2
T2782
98%
Catharanthine-d3 is an isotope labeled precursor of Vinblastine-type alkaloids.
CATHARANTHINE HEMITARTRATE
CAS:4168-17-6
Formula: C25H30N2O8
T3013
95%
Extracted?from?whole herb of Catharanthus roseus (L.)G.Don;Store?the?product?in?sealed,?cool?and?dry?condition
CATHARANTHINE SULFATE
CAS:70674-90-7
Formula: C21H26N2O6S
T3023
98%
Catharanthine inhibits nicotinic receptor mediated diaphragm contractions.
CATHEPSIN INHIBITOR 1
CAS:225120-65-0
Formula: C20H24ClN5O2
T6015
98%
Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
CAUDATIN
CAS:38395-02-7
Formula: C28H42O7
T3150
98%
Caudatin, one of the species of C-21 steroidal glycosides mainly isolated from the root of Cynanchum bungei Decne, exhibits potent anticancer activities.
CAY10505
CAS:1218777-13-9
Formula: C14H8FNO3S
T6433
98%
CAY10505 is dehydroxyl of AS-252424, which is a PI3K? inhibitor with IC50 of 33 nM.
CAY10603
CAS:1045792-66-2
Formula: C22H30N4O6
T1983
98%
CAY10603 is a potent and selective inhibitor of HDAC6 with IC50 of 2 pM, as compared with 271, 252, 0.42, 6851, and 90.7 nM for HDAC1, 2, 3, 8, and 10, respectively.
CAY10683 (SANTACRUZAMATE A)
CAS:1477949-42-0
Formula: C15H22N2O3
T2266
98%
Santacruzamate A (CAY10683) is a potent and selective HDAC inhibitor with IC50 of 119 pM for HDAC2, >3600-fold selectivity over other HDACs.
CB6837345
CAS:76822-21-4
Formula: C9H10O5
T3227
N/A
CCG 50014
CAS:883050-24-6
Formula: C16H13FN2O2S
T6434
98%
CCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.
CCG-1423
CAS:285986-88-1
Formula: C18H13ClF6N2O3
T2014
98%
CCG-1423 is a specific RhoA pathway inhibitor, which inhibits SRF-mediated transcription.
CCT 137690
CAS:1095382-05-0
Formula: C26H31BrN8O
T2611
100%
CCT137690 is a highly selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 15 nM, 25 nM and 19 nM. It has little effect on hERG ion-channel.
CCT007093
CAS:176957-55-4
Formula: C15H12OS2
T1927
98%
CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 M.
CCT128930
CAS:885499-61-6
Formula: C18H20ClN5
T6303
98%
CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinase.
CCT129202
CAS:942947-93-5
Formula: C23H25ClN8OS
T6435
98%
CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 M, 0.198 M and 0.227 M, respectively. It is less potent to FGFR3, GSK3, PDGFR, etc.
CDK4-IN-1
CAS:1256963-02-6
Formula: C22H29ClN8
T2082
98%
CDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 nM; 1500 and 500 fold than CDK1/Cyclin B (IC50>15 uM) and CDK2/Cyclin A (IC50=5.265 uM) respectively.
CEDIRANIB
CAS:288383-20-0
Formula: C25H27FN4O3
T2500
100%
Cediranib (AZD2171) is a highly potent VEGFR(KDR) inhibitor with IC50 of<1 3="" 4="" 5="" also="" inhibits="" with="" ic50="" of="" similar="" activity="&
CEDRYL ACETATE
CAS:77-54-3
Formula: C17H28O2
T2956
80%
The fungal transformation of cedryl acetate was investigated for the first time by using Cunninghamella elegans.
CEFACLOR MONOHYDRATE
CAS:70356-03-5
Formula: C15H16CIN3O5S
T1495
98%
Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.
CEFADROXIL
CAS:50370-12-2
Formula: C16H17N3O5S
T0366
95%
Long-acting, broad-spectrum, water-soluble, cephalexin derivative.
CEFALEXINE EP IMPURITY B
CAS:22252-43-3
Formula: C8H10N2O3S
T1364
98%
7-Aminodesacetoxycephalosporanic Acid and its derivates are used as antibiotics.
CEFAZOLIN SODIUM
CAS:27164-46-1
Formula: C14H13N8NaO4S3
T0953
97%
A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.
CEFDINIR
CAS:91832-40-5
Formula: C14H13N5O5S2
T0133
99%
Cefdinir is a bacteriocidal antibiotic.
CEFDITOREN PIVOXIL
CAS:117467-28-4
Formula: C25H28N6O7S3
T1405
98%
Cefditoren is a third-generation cephalosporin antibiotic for oral use. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.
CEFEPIME DIHYDROCHLORIDE MONOHYDRATE
CAS:123171-59-5
Formula: C19H24N6O5S22HClH2O
T0868
82.5%~91.1%
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria, with greater activity against both Gram-negative and Gram-positive organisms than t
CEFIXIME
CAS:79350-37-1
Formula: C16H15N5O7S2
T0932
99%
Cefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the pres
CEFMENOXIME HYDROCHLORIDE
CAS:75738-58-8
Formula: C16H18ClN9O5S3
T1190
99%
A cephalosporin antibiotic that is administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganisms, is a potent inhibitor of Enterobacteriaceae, and is highly resistant to hydrolysis by beta-l
CEFMETAZOLE SODIUM
CAS:56796-39-5
Formula: C15H16N7NaO5S3
T1070
92%
A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.
CEFONICID SODIUM
CAS:61270-78-8
Formula: C18H16N6Na2O8S3
T1228
98%
A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone
CEFOPERAZONE
CAS:62893-19-0
Formula: C25H27N9O8S2
T6437
98%
Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217G uptake with IC50 of 199 M.
CEFOPERAZONE SODIUM
CAS:62893-20-3
Formula: C25H26N9NaO8S2
T1218
85%
Semisynthetic broad-spectrum cephalosporin with a tetrazolyl moiety that is resistant to beta-lactamase. It has been proposed especially against Pseudomonas infections.
CEFOSELIS SULFATE
CAS:122841-12-7
Formula: C19H22N8O6S2H2SO4
T6438
98%
Cefoselis is a widely used beta-lactam antibiotic.
CEFOTAXIME SODIUM SALT
CAS:64485-93-4
Formula: C16H16N5NaO7S2
T0911
97%
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in term
CEFOTIAM HYDROCHLORIDE
CAS:66309-69-1
Formula: C18H23N9O4S3HCl
T1616
800ug/mg
One of the CEPHALOSPORINS that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms. .
CEFOXITIN SODIUM
CAS:33564-30-6
Formula: C16H16N3NaO7S2
T1023
98%
A semisynthetic cephamycin antibiotic resistant to beta-lactamase.
CEFPIRAMIDE ACID
CAS:70797-11-4
Formula: C25H24N8O7S2
T0138
98%
Cefpiramide is a third-generation cephalosporin antibiotic.
CEFPROZIL MONOHYDRATE
CAS:121123-17-9
Formula: C18H21N3O6S
T1118
99%
Cefprozil hydrate (Cefzil) is a second-generation cephalosporin type antibiotic.
CEFRADINE
CAS:38821-53-3
Formula: C16H19N3O4S
T0199
88%
Cephradine anhydrous is a Cephalosporin Antibacterial. The chemical classification of cephradine anhydrous is Cephalosporins.
CEFSULODINE SODIUM
CAS:52152-93-9
Formula: C22H19N4NaO8S2
T0827
95%
A pyridinium-substituted semisynthetic, broad-spectrum antibacterial used especially for Pseudomonas infections in debilitated patients.
CEFTAZIDIME
CAS:72558-82-8
Formula: C22H22N6O7S2
T1305
contains ca.10% Na2CO3
Semisynthetic, broad-spectrum antibacterial derived from CEPHALORIDINE and used especially for Pseudomonas and other gram-negative infections in debilitated patients.
CEFTIOFUR HCL
CAS:103980-44-5
Formula: C19H17N5O7S3HCl
T6268
98%
Ceftiofur HCl is a cephalosporin antibiotic, used to treat both Gram-positive and Gram-negative bacteria infection.
CEFTIOFUR SODIUM
CAS:104010-37-9
Formula: C19H16N5NaO7S3
T0198
99%
Ceftiofur is a broad spectrum cephalosporin.
CEFTRIAXONE SODIUM HYDRATE
CAS:104376-79-6
Formula: C18H16N8Na2O7S3,31/2H2O
T1223
980ug/mg
A broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.
CEFUROXIME SODIUM
CAS:56238-63-2
Formula: C16H15N4NaO8S
T1224
855ug/MG,USP30
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, GONORRHEA, and HAEMOPHILUS.
CELASTROL
CAS:34157-83-0
Formula: C29H38O4
T3028
99%+
Celastrol is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 M.
CELECOXIB
CAS:169590-42-5
Formula: C17H14F3N3O2S
T0466
98%
Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial
CELIPROLOL HYDROCHLORIDE
CAS:57470-78-7
Formula: C20H33N3O4HCl
T1244
98%
A cardioselective beta-1 adrenergic antagonist that has intrinsic symopathomimetic activity. It is used in the management of ANGINA PECTORIS and HYPERTENSION.
CEP-18770 (DELANZOMIB)
CAS:847499-27-8
Formula: C21H28BN3O5
T6027
98%
CEP-18770 (Delanzomib) is an orally active inhibitor of the chymotrypsin-like activity of proteasome with IC50 of 3.8 nM, with only marginal inhibition of the tryptic and peptidylglutamyl activities of the proteosome. Phase 1/2.
CEP-28122
CAS:1022958-60-6
Formula: C28H35ClN6O3
T2612
100%
A selective ALK inhibitor (CEP28122) resulted in a significant clinical response of hPDT mice.
CEP-32496
CAS:1188910-76-0
Formula: C24H22F3N5O5
T2070
98%
CEP-32496 is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/36 nM and 39 nM, also potent to Abl-1, c-Kit, Ret, PDGFR and VEGFR2, respectively; insignificant affinity for MEK-1, MEK-2, ERK-1 and ERK-2. Phase 1/2.
CEP-33779
CAS:1346168-57-7
Formula: C24H26N6O2S
T2426
98%
CEP-33779 is a novel selective JAK2 inhibitor.
CEP-37440
CAS:1391712-60-9
Formula: C30H38ClN7O3
T2655
100%
CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma).
CEPAZINE
CAS:64544-07-6
Formula: C20H22N4O10S
T1227
98%
Cefuroxime axetil is a second generation oral cephalosporin antibiotic. It was discovered by Glaxo now GlaxoSmithKline and introduced in 1987 as Zinnat.
CEPHALEXIN
CAS:15686-71-2
Formula: C16H17N3O4S
T1008
98%
A semisynthetic cephalosporin antibiotic with antimicrobial activity similar to that of CEPHALORIDINE or CEPHALOTHIN, but somewhat less potent. It is effective against both gram-positive and gram-negative organisms.
CEPHALOMANNINE
CAS:71610-00-9
Formula: C45H53NO14
T2217
98%
Cephalomannine is an active anti-cancer agent obtained from Taxus yunnanensis and has an antineoplastic effect on tumors found in mice.
CEPHALONIUM
CAS:5575-21-3
Formula: C20H18N4O5S2
T0141
99%
Cefalonium (INN) is a first-generation cephalosporin antibiotic.
CEPHALOTHIN SODIUM
CAS:58-71-9
Formula: C16H15N2NaO6S2
T1122
98%
A cephalosporin antibiotic.
CEPHARANTHINE
CAS:481-49-2
Formula: C37H38N2O6
T0131
98%
Cepharanthine is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-a-mediated NF?B stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production.
CERDULATINIB
CAS:1198300-79-6
Formula: C20H27N7O3S
T2487
98%
Cerdulatinib(PRT-062070; PRT2070) is an novel oral dual Syk/JAK inhibitor.
CERDULATINIB (PRT062070, PRT2070)
CAS:1369761-01-2
Formula: C20H28ClN7O3S
T6104
98%
Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM.
CETIRIZINE DIHYDROCHLORIDE
CAS:83881-52-1
Formula: C21H27Cl3N2O3
T0089
98%
Cetirizine dihydrochloride is a potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or
CETYLPYRIDINIUM CHLORIDE MONOHYDRATE
CAS:6004-24-6
Formula: C21H38ClN
T0900
98%
Cetylpyridinium chloride (CPC) is a cationic quaternary ammonium compound used in some types of mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. It is an antiseptic that kills bacteria and other microorganisms. It has be
CEVIMELINE HYDROCHLORIDE HEMIHYDRATE
CAS:153504-70-2
Formula: C20H38Cl2N2O3S2
T2390
98%
Cevimeline hydrochloride hemihydrate, a novel muscarinic receptor agonist, is a candidate therapeutic drug for xerostomia in Sjogren's syndrome.
CFTR(INH)-172
CAS:307510-92-5
Formula: C18H10F3NO3S2
T2355
98%
CFTRinh-172 is a voltage-independent, selective CFTR inhibitor with Ki of 300 nM, showing no effects on MDR1, ATP-sensitive K+ channels, or a series of other transporters.
CGI-1746
CAS:910232-84-7
Formula: C34H37N5O4
T2472
98%
CGI1746 is a potent and highly selective small-molecule inhibitor of the Btk with IC50 of 1.9 nM.
CGK733
CAS:905973-89-9
Formula: C23H18Cl3FN4O3S
T1821
98%
CGK 733 is a potent and selective inhibitor of ATM/ATR with IC50 of ~200 nM.
CGP 57380
CAS:522629-08-9
Formula: C11H9FN6
T6440
98%
CGP 57380 is a potent MNK1 inhibitor with IC50 of 2.2 M, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases.
CGS 21680 HCL
CAS:124431-80-7
Formula: C23H29N7O6.HCl
T6441
98%
CGS 21680 HCl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor.
CH-223191
CAS:301326-22-7
Formula: C19H19N5O
T2448
98%
CH-223191 is a potent and specific aryl hydrocarbon receptor (AhR) antagonist with IC50 of 30 nM.
CH5132799
CAS:1007207-67-1
Formula: C15H19N7O3S
T2619
100%
CH5132799 inhibits class I PI3Ks, particularly PI3Ka with IC50 of 14 nM; less potent to PI3Kd?, while sensitive in PIK3CA mutations cell lines. Phase 1.
CH5138303
CAS:959763-06-5
Formula: C19H18ClN5O2S
T6442
98%
CH5138303 is an orally available Hsp90 inhibitor with Kd of 0.48 nM.
CH5183284 (DEBIO-1347)
CAS:1265229-25-1
Formula: C20H16N6O
T6024
98%
CH5183284 is a selective and orally available FGFR inhibitor with IC50 of 9.3 nM, 7.6 nM, 22 nM, and 290 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. Phase 1.
CH5424802
CAS:1256580-46-7
Formula: C30H34N4O2
T1936
98%
CH5424802(AF 802; Alectinib) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation.
CHEMBL460860
CAS:82373-94-2
Formula: C20H22O9
T2964
98%
Extracted?from?caulis polygoni multiflori;Store?the?product?in?sealed,?cool?and?dry?condition
CHENODEOXYCHOLIC ACID
CAS:474-25-9
Formula: C24H40O4
T0847
98%
A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve galls
CHICAGO SKY BLUE 6B
CAS:2610-05-1
Formula: C34H24N6Na4O16S4
T2194
Chicago sky blue 6B, a vesicular glutamate transporters inhibitor, attenuates methamphetamine-induced hyperactivity and behavioral sensitization in mice.
CHIDAMIDE
CAS:743420-02-2
Formula: C22H19FN4O2
T2025
98%
Chidamide(CS055; HBI-8000) is a class I HDAC inhibitor with IC50s of 95/160/67/733 nM for HDAC1/2/3/8; also inhibits HDAC10/11(IC50=78/432 nM); no inhibition on HDAC4/5/7/9/6(IC50>30 uM).
CHIR-124
CAS:405168-58-3
Formula: C23H22ClN5O
T6350
98%
CHIR-124 is a novel and potent Chk1 inhibitor with IC50 of 0.3 nM. It shows 2,000-fold selectivity against Chk2, 500- to 5,000-fold less activity against CDK2/4 and Cdc2.
CHIR-98014
CAS:252935-94-7
Formula: C20H17Cl2N9O2
T2608
99%
CHIR-98014 is a potent GSK-3a/ inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
CHIR-99021
CAS:252917-06-9
Formula: C22H18Cl2N8
T2310
98%
CHIR-99021 (CT99021) is a GSK-3a and GSK-3 inhibitor with IC50 of 10 nM and 6.7 nM, respectively.
CHIR98014
CAS:556813-39-9
Formula: C20H17Cl2N9O2
T3074
99%
CHIR-98014 is a potent GSK-3a/ inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
CHITOSAN
CAS:9012-76-4
Formula: C6H11NO4X2
T1715
98%
Chitosan is a linear polysaccharide composed of randomly distributed -(1-4)-linked D-glucosamine (deacetylated unit) and N-acetyl-D-glucosamine
CHLOQUINAN
CAS:72-80-0
Formula: C10H7Cl2NO
T0908
98%
Local anti-infective agent used for skin, gastrointestinal, and vaginal infections with fungi, protozoa, and certain bacteria. In animals, it causes central nervous system damage and is not administered parenterally. It is also used as antiseptic, fungist
CHLORAL HYDRATE
CAS:302-17-0
Formula: C2H3Cl3O2
T0779
98%
Chloral Hydrate is a synthetic monohydrate of chloral with sedative, hypnotic, and anticonvulsive properties. Chloral hydrate is converted to the active compound trichloroethanol by hepatic alcohol dehydrogenase. The agent interacts with various neurotran
CHLORALOSE
CAS:15879-93-3
Formula: C8H11Cl3O6
T1315
98%
A derivative of CHLORAL HYDRATE that was used as a sedative but has been replaced by safer and more effective drugs. Its most common use is as a general anesthetic in animal experiments.
CHLORAMBUCIL
CAS:305-03-3
Formula: C14H19Cl2NO2
T0975
99%
A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report o
CHLORAMINE-T
CAS:127-65-1
Formula: C7H7ClNNaO2S
T0669
99%
Tosylchloramide or N-chloro tosylamide, sodium salt, sold as chloramine-T, is a N-chlorinated and N-deprotonated sulfonamide used as a biocide and a mild disinfectant. It is a white powder that gives unstable solutions with water.
CHLORAMPHENICOL
CAS:56-75-7
Formula: C11H12Cl2N2O5
T1205
99%
An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein
CHLORHEXIDINE
CAS:55-56-1
Formula: C22H30Cl2N10
T1000
98%
A disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
CHLORHEXIDINE ACETATE
CAS:56-95-1
Formula: C24H34Cl2N10O2
T1000L
98%
Chlorhexidine acetate is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
CHLORHEXIDINE DIHYDROCHLORIDE
CAS:3697-42-5
Formula: C22H32Cl4N10
T1147
98%
Chlorhexidine hydrochloride is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms.
CHLORINDANOL
CAS:145-94-8
Formula: C9H9ClO
T1253
98%
Chlorindanol is an organic compound with molecular fomula C9H9ClO.
Chlorindione
CAS:1146-99-2
Formula: C15H9ClO2
T0360
97%
Clorindione is a vitamin K antagonist. It is a derivative of phenindione.
CHLORMADINONE ACETATE
CAS:302-22-7
Formula: C23H29ClO4
T1596
98%
An orally active synthetic progestational hormone used often in combinations as an oral contraceptive.
CHLORMEZANONE
CAS:80-77-3
Formula: C11H12ClNO3S
T0715
98%
A non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
CHLOROBENZOTHIAZOLINONE
CAS:20600-44-6
Formula: C7H4ClNOS
T0577
98%
Also called 5-Chloro-2-benzothiazolinone
CHLOROBUTANOL
CAS:57-15-8
Formula: C4H7ClO1/2H2O
T0901
98%
Chlorobutanol is a chemical preservative, sedative hypnotic and weak local anaesthetic similar in nature to chloral hydrate. It has antibacterial and antifungal properties. Chlorobutanol is typically used at a concentration of 0.5% where it lends long ter
CHLOROGENIC ACID
CAS:327-97-9
Formula: C16H18O9
T2805
98%
Extracted from Lonicera acuminata.Wall.;Suitability:Ethanol and acetone;Store the product in sealed,cool and dry condition
CHLOROPHYLLIN SODIUM COPPER SALT
CAS:11006-34-1
Formula: C34H31CuN4Na3O6
T1254
95%
Chlorophyllin refers to any one of a group of closely related water-soluble salts that are semi-synthetic derivatives of chlorophyll, differing in the identity of the cations associated with the anion. Its most common form is a sodium/copper derivative us
CHLOROPROCAINE HCL
CAS:3858-89-7
Formula: C13H20Cl2N2O2
T6443
98%
Chloroprocaine HCl is a local anesthetic during surgical procedures.
CHLOROPYRAMINE HYDROCHLORIDE
CAS:6170-42-9
Formula: C16H20ClN3HCl
T0263
98%
Chloropyramine is a first generation antihistamine drug approved in some Eastern European countries for the treatment of allergic conjunctivitis, allergic rhinitis, bronchial asthma, and other atopic (allergic) conditions. Related indications for clinical
CHLOROQUINE DIPHOSPHATE
CAS:50-63-5
Formula: C18H26CLN32(H3PO4)
T0194
98%+
Chloroquine diphosphate is used as an antimalarial drug and also functions to increase sensitivity of tumor cells to radiation and chemotherapy via inducing autophagy [1]. Chloroquine diphosphate has been reported as an adjuvant for radiation and chemothe
CHLOROTHIAZIDE
CAS:58-94-6
Formula: C7H6ClN3O4S2
T0677
99%
Chlorothiazide is a diuretic and antihypertensive.
CHLOROTRIANISENE
CAS:569-57-3
Formula: C23H21ClO3
T2569
100%
Chlorotrianisene is a powerful synthetic, non-steroidal estrogen.
CHLOROXINE
CAS:773-76-2
Formula: C9H5Cl2NO
T0500
98%
Chloroxine is a synthetic antibacterial compound that is effective in the treatment of dandruff and seborrheic dermatitis when incorporated in a shampoo.
CHLORPHENIRAMINE MALEATE
CAS:113-92-8
Formula: C20H23ClN2O4
T1553
98%
Chlorpheniramine (Chlorpheniramine maleate, Chlorphenamine) is an histamine H1 receptor antagonist .
CHLORPROMAZINE HYDROCHLORIDE
CAS:69-09-0
Formula: C17H19ClN2SHCl
T1384
98%
Chlorpromazine hydrochloride is a dopamine and potassium channel inhibitor used as the prototypical phenothiazine antipsychotic drug.
CHLORPROPAMIDE
CAS:94-20-2
Formula: C10H13ClN2O3S
T0490
98%
Chlorpropamide is a sulfonylurea class drug for type 2 diabetes mellitus.
CHLORPROTHIXENE
CAS:113-59-7
Formula: C18H18ClNS
T0074
98%
Chlorprothixene is a typical antipsychotic drug of the thioxanthene class and was the first of the series to be synthesized.
CHLORPROTHIXENE HYDROCHLORIDE
CAS:6469-93-8
Formula: C18H18ClNSHCl
T0074L
98%
Chlorprothixene is a typical antipsychotic drug of the thioxanthene (tricyclic) class. Chlorprothixene exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors.
CHLORTETRACYCLINE HYDROCHLORIDE
CAS:64-72-2
Formula: C22H23ClN2O8HCl
T1304
95%
Chlortetracycline hydrochloride is the first identified tetracycline antibiotic.
CHLORTHALIDONE
CAS:77-36-1
Formula: C14H11ClN2O4S
T1091
98%
Chlorthalidone is a thiazide-like diuretic used to treat hypertension.
CHLORZOXAZONE
CAS:95-25-0
Formula: C7H4ClNO2
T1650
98%
BIIB021(CNF2024) is an orally available, fully synthetic small-molecule inhibitor of HSP90 with Ki and EC50 of 1.7 nM and 38 nM, respectively.
CHOLESTEROL
CAS:57-88-5
Formula: C27H46O
T0760
95%
The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
CHOLESTERYL ACETATE
CAS:604-35-3
Formula: C29H48O2
T2918
97%
n/a
CHOLIC ACID
CAS:81-25-4
Formula: C24H40O5
T2963
98%
ApplicationNon-denaturing ionic detergent used for extraction of membrane proteins. ActionsBile AcidPackaging1 kg in poly bottle25,100,500 g in poly bottle
CHOLINE CHLORIDE
CAS:67-48-1
Formula: C5H14ClNO
T1039
98%
A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
CHONDROITINE SULFATE
CAS:9007-28-7
Formula: C13H21NO15S
T2980
95%
Extracted from shark bone;Store the product in sealed, cool and dry condition
CHROMOCARB
CAS:4940-39-0
Formula: C10H6O4
T0259
97%
Chromocarb is a vascular protective agent used in the treatment of venous disorders and microvascular affections. Peroral treatment of rats with Chromocarb significantly reduces the degradation of the vascular wall by intravenous collagenase. Chromocarb t
CHRYSIN
CAS:480-40-0
Formula: C15H10O4
T2837
100%
Chrysin is a naturally occurring flavone chemically extracted from the blue passion flower (Passiflora caerulea).
CHRYSOPHANIC ACID
CAS:481-74-3
Formula: C15H10O4
T2995
100%
Extracted from Rheum palmatum L.;Suitability:Boiling ethanol,benzene,chloroform,ether,acetic acid and acetone;Store the product in sealed,cool and dry condition
CI-1040
CAS:212631-79-3
Formula: C17H14ClF2IN2O2
T2443
98%+
PD184352 (CI-1040) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM in cell-based assays, 100-fold more selective for MEK1/2 than MEK5. Phase 2.
CI-994
CAS:112522-64-2
Formula: C15H15N3O2
T1888
98%
CI-994 (Tacedinaline) is an anti-cancer drug which inhibits HDAC1 with IC50 of 0.57 M and causes G1 cell cycle arrest.
CICLESONIDE
CAS:126544-47-6
Formula: C32H44O7
T2526
98%
Ciclesonide(RPR251526) is a glucocorticoid used to treat obstructive airway diseases.


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